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Items: 1 to 20 of 61

1.

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease.

Kikuchi K, Saigusa D, Kanemitsu Y, Matsumoto Y, Thanai P, Suzuki N, Mise K, Yamaguchi H, Nakamura T, Asaji K, Mukawa C, Tsukamoto H, Sato T, Oikawa Y, Iwasaki T, Oe Y, Tsukimi T, Fukuda NN, Ho HJ, Nanto-Hara F, Ogura J, Saito R, Nagao S, Ohsaki Y, Shimada S, Suzuki T, Toyohara T, Mishima E, Shima H, Akiyama Y, Akiyama Y, Ichijo M, Matsuhashi T, Matsuo A, Ogata Y, Yang CC, Suzuki C, Breeggemann MC, Heymann J, Shimizu M, Ogawa S, Takahashi N, Suzuki T, Owada Y, Kure S, Mano N, Soga T, Wada T, Kopp JB, Fukuda S, Hozawa A, Yamamoto M, Ito S, Wada J, Tomioka Y, Abe T.

Nat Commun. 2019 Apr 23;10(1):1835. doi: 10.1038/s41467-019-09735-4.

2.

Impaired antigen-specific lymphocyte priming in mice after Toll-like receptor 4 activation via induction of monocytic myeloid-derived suppressor cells.

Tsukamoto H, Kozakai S, Kobayashi Y, Takanashi R, Aoyagi T, Numasaki M, Ohta S, Tomioka Y.

Eur J Immunol. 2019 Apr;49(4):546-563. doi: 10.1002/eji.201847805. Epub 2019 Feb 1.

PMID:
30671932
3.

Generation and Characterization of Anti-phenyl Sulfate Monoclonal Antibodies and a Potential Use for Phenyl Sulfate Analysis in Human Blood.

Kanemitsu Y, Tsukamoto H, Matsumoto Y, Nozawa-Kumada K, Kondo Y, Abe T, Tomioka Y.

Biol Pharm Bull. 2018;41(8):1170-1177. doi: 10.1248/bpb.b17-00925.

4.

Detection of novel metabolite for roxadustat doping by global metabolomics.

Saigusa D, Suzuki N, Matsumoto Y, Umeda K, Tomioka Y, Koshiba S, Yamamoto M.

J Biochem. 2018 Jun 1;163(6):e1. doi: 10.1093/jb/mvy036. No abstract available.

PMID:
29771375
5.

Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKKϵ-IRF3 axis activation.

Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.

J Biol Chem. 2018 Jun 29;293(26):10186-10201. doi: 10.1074/jbc.M117.796631. Epub 2018 May 14.

PMID:
29760187
6.

The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice.

Izumi H, Shinoda Y, Saito T, Saido TC, Sato K, Yabuki Y, Matsumoto Y, Kanemitsu Y, Tomioka Y, Abolhassani N, Nakabeppu Y, Fukunaga K.

Neuroscience. 2018 May 1;377:87-97. doi: 10.1016/j.neuroscience.2018.02.031. Epub 2018 Mar 3.

PMID:
29510211
7.

Detection of novel metabolite for Roxadustat doping by global metabolomics.

Saigusa D, Suzuki N, Matsumoto Y, Umeda K, Tomioka Y, Koshiba S, Yamamoto M.

J Biochem. 2018 Feb 9. doi: 10.1093/jb/mvy028. [Epub ahead of print]

PMID:
29438490
8.

Impact of the Oral Adsorbent AST-120 on Organ-Specific Accumulation of Uremic Toxins: LC-MS/MS and MS Imaging Techniques.

Sato E, Saigusa D, Mishima E, Uchida T, Miura D, Morikawa-Ichinose T, Kisu K, Sekimoto A, Saito R, Oe Y, Matsumoto Y, Tomioka Y, Mori T, Takahashi N, Sato H, Abe T, Niwa T, Ito S.

Toxins (Basel). 2017 Dec 28;10(1). pii: E19. doi: 10.3390/toxins10010019.

9.

Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model.

Mishima E, Fukuda S, Kanemitsu Y, Saigusa D, Mukawa C, Asaji K, Matsumoto Y, Tsukamoto H, Tachikawa T, Tsukimi T, Fukuda NN, Ho HJ, Kikuchi K, Suzuki C, Nanto F, Suzuki T, Ito S, Soga T, Tomioka Y, Abe T.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F824-F833. doi: 10.1152/ajprenal.00314.2017. Epub 2017 Nov 22.

PMID:
29167170
10.

Simultaneous quantitative analysis of uremic toxins by LC-MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column.

Kanemitsu Y, Asaji K, Matsumoto Y, Tsukamoto H, Saigusa D, Mukawa C, Tachikawa T, Abe T, Tomioka Y.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Nov 15;1068-1069:1-8. doi: 10.1016/j.jchromb.2017.10.009. Epub 2017 Oct 5.

PMID:
29024911
11.

An inhibitory epitope of human Toll-like receptor 4 resides on leucine-rich repeat 13 and is recognized by a monoclonal antibody.

Tsukamoto H, Yamagata Y, Ukai I, Takeuchi S, Okubo M, Kobayashi Y, Kozakai S, Kubota K, Numasaki M, Kanemitsu Y, Matsumoto Y, Tomioka Y.

FEBS Lett. 2017 Sep;591(18):2953. doi: 10.1002/1873-3468.12837. No abstract available.

12.

An inhibitory epitope of human Toll-like receptor 4 resides on leucine-rich repeat 13 and is recognized by a monoclonal antibody.

Tsukamoto H, Yamagata Y, Ukai I, Takeuchi S, Okubo M, Kobayashi Y, Kozakai S, Kubota K, Numasaki M, Kanemitsu Y, Matsumoto Y, Tomioka Y.

FEBS Lett. 2017 Aug;591(16):2406-2416. doi: 10.1002/1873-3468.12768. Epub 2017 Aug 8. Erratum in: FEBS Lett. 2017 Sep;591(18):2953. Mumasaki, Muneo [corrected to Numasaki, Muneo].

13.

Ginsenoside Rg1 alleviates corticosterone-induced dysfunction of gap junctions in astrocytes.

Xia CY, Chu SF, Zhang S, Gao Y, Ren Q, Lou YX, Luo P, Tian MT, Wang ZQ, Du GH, Tomioka Y, Yamakuni T, Zhang Y, Wang ZZ, Chen NH.

J Ethnopharmacol. 2017 Aug 17;208:207-213. doi: 10.1016/j.jep.2017.06.031. Epub 2017 Jun 20.

PMID:
28642095
14.

Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases.

Matsuhashi T, Sato T, Kanno SI, Suzuki T, Matsuo A, Oba Y, Kikusato M, Ogasawara E, Kudo T, Suzuki K, Ohara O, Shimbo H, Nanto F, Yamaguchi H, Saigusa D, Mukaiyama Y, Watabe A, Kikuchi K, Shima H, Mishima E, Akiyama Y, Oikawa Y, Hsin-Jung HO, Akiyama Y, Suzuki C, Uematsu M, Ogata M, Kumagai N, Toyomizu M, Hozawa A, Mano N, Owada Y, Aiba S, Yanagisawa T, Tomioka Y, Kure S, Ito S, Nakada K, Hayashi KI, Osaka H, Abe T.

EBioMedicine. 2017 Jun;20:27-38. doi: 10.1016/j.ebiom.2017.05.016. Epub 2017 May 13.

15.

A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathways.

Shima H, Sasaki K, Suzuki T, Mukawa C, Obara T, Oba Y, Matsuo A, Kobayashi T, Mishima E, Watanabe S, Akiyama Y, Kikuchi K, Matsuhashi T, Oikawa Y, Nanto F, Akiyama Y, Ho HJ, Suzuki C, Saigusa D, Masamune A, Tomioka Y, Masaki T, Ito S, Hayashi KI, Abe T.

Sci Rep. 2017 May 15;7(1):1884. doi: 10.1038/s41598-017-01702-7.

16.

Tyrosine hydroxylase gene expression is facilitated by alcohol followed by the degradation of the protein by ubiquitin proteasome system.

Kawahata I, Evelyn GR, Huinan X, Ohtaku S, Tomioka Y, Yamakuni T.

Neuro Endocrinol Lett. 2017 Feb;38(1):43-49.

PMID:
28456147
17.

Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS-based metabolomics approach.

Mishima E, Fukuda S, Mukawa C, Yuri A, Kanemitsu Y, Matsumoto Y, Akiyama Y, Fukuda NN, Tsukamoto H, Asaji K, Shima H, Kikuchi K, Suzuki C, Suzuki T, Tomioka Y, Soga T, Ito S, Abe T.

Kidney Int. 2017 Sep;92(3):634-645. doi: 10.1016/j.kint.2017.02.011. Epub 2017 Apr 8.

18.

Licochalcones extracted from Glycyrrhiza inflata inhibit platelet aggregation accompanied by inhibition of COX-1 activity.

Okuda-Tanino A, Sugawara D, Tashiro T, Iwashita M, Obara Y, Moriya T, Tsushima C, Saigusa D, Tomioka Y, Ishii K, Nakahata N.

PLoS One. 2017 Mar 10;12(3):e0173628. doi: 10.1371/journal.pone.0173628. eCollection 2017.

19.

A Heterodimeric Cytokine, Consisting of IL-17A and IL-17F, Promotes Migration and Capillary-Like Tube Formation of Human Vascular Endothelial Cells.

Numasaki M, Tsukamoto H, Tomioka Y, Nishioka Y, Ohrui T.

Tohoku J Exp Med. 2016 Sep;240(1):47-56. doi: 10.1620/tjem.240.47.

20.

[A CASE OF ANAPHYLAXIS IN THE PEDIATRIC PATIENT WITH MILK ALLERGY DUE TO TRACES OF MILK PROTEIN IN THE LACTOSE USED AS AN EXCIPIENT OF INAVIR INHALATION].

Morikawa M, Kanemitsu Y, Tsukamoto H, Morikawa A, Tomioka Y.

Arerugi. 2016 May;65(3):200-5. doi: 10.15036/arerugi.65.200. Japanese.

PMID:
27193929

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