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Items: 1 to 20 of 78


A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.

Kesselring L, Miskey C, Zuliani C, Querques I, Kapitonov V, Laukó A, Fehér A, Palazzo A, Diem T, Lustig J, Sebe A, Wang Y, Dinnyés A, Izsvák Z, Barabas O, Ivics Z.

Nucleic Acids Res. 2019 Nov 28. pii: gkz1119. doi: 10.1093/nar/gkz1119. [Epub ahead of print]


Clinical characteristics of neonatal fulminant necrotizing enterocolitis in a tertiary Children's hospital in the last 10 years.

Lin L, Xia X, Liu W, Wang Y, Hua Z.

PLoS One. 2019 Nov 8;14(11):e0224880. doi: 10.1371/journal.pone.0224880. eCollection 2019.


Correction: Suicidal Autointegration of Sleeping Beauty and piggyBac Transposons in Eukaryotic Cells.

Wang Y, Wang J, Devaraj A, Singh M, Jimenez Orgaz A, Chen JX, Selbach M, Ivics Z, Izsvák Z.

PLoS Genet. 2019 Sep 23;15(9):e1008406. doi: 10.1371/journal.pgen.1008406. eCollection 2019 Sep.


Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning.

Wang D, Zhang C, Wang B, Li B, Wang Q, Liu D, Wang H, Zhou Y, Shi L, Lan F, Wang Y.

Nat Commun. 2019 Sep 19;10(1):4284. doi: 10.1038/s41467-019-12281-8.


Cas12aVDet: A CRISPR/Cas12a-Based Platform for Rapid and Visual Nucleic Acid Detection.

Wang B, Wang R, Wang D, Wu J, Li J, Wang J, Liu H, Wang Y.

Anal Chem. 2019 Oct 1;91(19):12156-12161. doi: 10.1021/acs.analchem.9b01526. Epub 2019 Sep 11.


MLP-deficient human pluripotent stem cell derived cardiomyocytes develop hypertrophic cardiomyopathy and heart failure phenotypes due to abnormal calcium handling.

Li X, Lu WJ, Li Y, Wu F, Bai R, Ma S, Dong T, Zhang H, Lee AS, Wang Y, Lan F.

Cell Death Dis. 2019 Aug 13;10(8):610. doi: 10.1038/s41419-019-1826-4.


MicroRNA-302d promotes the proliferation of human pluripotent stem cell-derived cardiomyocytes by inhibiting LATS2 in the Hippo pathway.

Xu F, Yang J, Shang J, Lan F, Li M, Shi L, Shen L, Wang Y, Ge J.

Clin Sci (Lond). 2019 Jul 2;133(13):1387-1399. doi: 10.1042/CS20190099. Print 2019 Jul 15.


MIR148A family regulates cardiomyocyte differentiation of human embryonic stem cells by inhibiting the DLL1-mediated NOTCH signaling pathway.

Fang X, Miao S, Yu Y, Ding F, Han X, Wu H, Zhao ZA, Wang Y, Hu S, Lei W.

J Mol Cell Cardiol. 2019 Sep;134:1-12. doi: 10.1016/j.yjmcc.2019.06.014. Epub 2019 Jun 22.


krCRISPR: an easy and efficient strategy for generating conditional knockout of essential genes in cells.

Wang B, Wang Z, Wang D, Zhang B, Ong SG, Li M, Yu W, Wang Y.

J Biol Eng. 2019 Apr 24;13:35. doi: 10.1186/s13036-019-0150-y. eCollection 2019.


Treatment with either COX-2 inhibitor or 5-LOX inhibitor causes no compensation between COX-2 pathway and 5-LOX pathway in chronic aluminum overload-induced liver injury in rats.

Xia H, He Q, Wang H, Wang Y, Yang Y, Li Y, Zhang J, Chen Z, Yang J.

Fundam Clin Pharmacol. 2019 Oct;33(5):535-543. doi: 10.1111/fcp.12465. Epub 2019 Apr 2.


Prediction of surgical management for operated adhesive postoperative small bowel obstruction in a pediatric population.

Deng Y, Wang Y, Guo C.

Medicine (Baltimore). 2019 Mar;98(11):e14919. doi: 10.1097/MD.0000000000014919.


Bacterial intracellular nanoparticles exhibiting antioxidant properties and the significance of their formation in ROS detoxification.

Pan Y, Wang Y, Fan X, Wang W, Yang X, Cui D, Zhao M.

Environ Microbiol Rep. 2019 Apr;11(2):140-146. doi: 10.1111/1758-2229.12733. Epub 2019 Jan 21.


Vertical Distribution of Bathyarchaeotal Communities in Mangrove Wetlands Suggests Distinct Niche Preference of Bathyarchaeota Subgroup 6.

Pan J, Chen Y, Wang Y, Zhou Z, Li M.

Microb Ecol. 2019 Feb;77(2):417-428. doi: 10.1007/s00248-018-1309-7. Epub 2019 Jan 5.


Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling.

Xie Y, Ma A, Wang B, Peng R, Jing Y, Wang D, Finnell RH, Qiao B, Wang Y, Wang H, Zheng Y.

Clin Sci (Lond). 2019 Jan 22;133(2):225-238. doi: 10.1042/CS20180842. Print 2019 Jan 31.


Author Correction: An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells.

Xie Y, Wang D, Lan F, Wei G, Ni T, Chai R, Liu D, Hu S, Li M, Li D, Wang H, Wang Y.

Sci Rep. 2018 Dec 12;8(1):17900. doi: 10.1038/s41598-018-36738-w.


The Association of Nil Per Os (NPO) Days with Necrotizing Enterocolitis.

Wang Y, Li X, Guo C.

Gastroenterol Res Pract. 2018 Oct 30;2018:2795468. doi: 10.1155/2018/2795468. eCollection 2018.


Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria.

Phillips J, Farrell C, Wang Y, Singal AK, Anderson K, Balwani M, Bissell M, Bonkovsky H, Seay T, Paw B, Desnick R, Bloomer J.

Mol Genet Metab. 2018 Oct 22. pii: S1096-7192(18)30587-0. doi: 10.1016/j.ymgme.2018.10.005. [Epub ahead of print]


Early postoperative outcomes of surgery for intestinal perforation in NEC based on intestinal location of disease.

Geng Q, Wang Y, Li L, Guo C.

Medicine (Baltimore). 2018 Sep;97(39):e12234. doi: 10.1097/MD.0000000000012234.


Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population.

Deng Q, Hao F, Wang Y, Guo C.

J Int Med Res. 2018 Dec;46(12):5195-5204. doi: 10.1177/0300060518794092. Epub 2018 Sep 10.


The association between visual creativity and cortical thickness in healthy adults.

Tian F, Chen Q, Zhu W, Wang Y, Yang W, Zhu X, Tian X, Zhang Q, Cao G, Qiu J.

Neurosci Lett. 2018 Sep 14;683:104-110. doi: 10.1016/j.neulet.2018.06.036. Epub 2018 Jun 21.


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