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Items: 1 to 20 of 73

1.

Role of Muscarinic Acetylcholine Signaling in Gastrointestinal Cancers.

Konishi M, Hayakawa Y, Koike K.

Biomedicines. 2019 Aug 10;7(3). pii: E58. doi: 10.3390/biomedicines7030058. Review.

2.

The Reduction in Gastric Atrophy after Helicobacter pylori Eradication Is Reduced by Treatment with Inhibitors of Gastric Acid Secretion.

Niikura R, Hayakawa Y, Hirata Y, Ogura K, Fujishiro M, Yamada A, Ushiku T, Konishi M, Fukayama M, Koike K.

Int J Mol Sci. 2019 Apr 18;20(8). pii: E1913. doi: 10.3390/ijms20081913.

3.

Alpha-Blockers As Colorectal Cancer Chemopreventive: Findings from a Case-Control Study, Human Cell Cultures, and In Vivo Preclinical Testing.

Suzuki N, Niikura R, Ihara S, Hikiba Y, Kinoshita H, Higashishima N, Hayakawa Y, Yamada A, Hirata Y, Nakata R, Okamoto M, Sano M, Kushiyama A, Ichinose M, Woods SL, Worthley D, Iwamoto Y, Koike K.

Cancer Prev Res (Phila). 2019 Mar;12(3):185-194. doi: 10.1158/1940-6207.CAPR-18-0288. Epub 2019 Jan 30.

PMID:
30700439
4.

Detection of Premalignant Gastrointestinal Lesions Using Surface-Enhanced Resonance Raman Scattering-Nanoparticle Endoscopy.

Harmsen S, Rogalla S, Huang R, Spaliviero M, Neuschmelting V, Hayakawa Y, Lee Y, Tailor Y, Toledo-Crow R, Kang JW, Samii JM, Karabeber H, Davis RM, White JR, van de Rijn M, Gambhir SS, Contag CH, Wang TC, Kircher MF.

ACS Nano. 2019 Feb 26;13(2):1354-1364. doi: 10.1021/acsnano.8b06808. Epub 2019 Feb 4.

5.

BHLHA15-Positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice.

Hayakawa Y, Tsuboi M, Asfaha S, Kinoshita H, Niikura R, Konishi M, Hata M, Oya Y, Kim W, Middelhoff M, Hikiba Y, Higashijima N, Ihara S, Ushiku T, Fukayama M, Tailor Y, Hirata Y, Guha C, Yan KS, Koike K, Wang TC.

Gastroenterology. 2019 Mar;156(4):1066-1081.e16. doi: 10.1053/j.gastro.2018.11.024. Epub 2018 Nov 15.

PMID:
30448068
6.

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.

Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC.

Cancer Cell. 2018 Nov 12;34(5):863-867. doi: 10.1016/j.ccell.2018.10.010. No abstract available.

7.

Gastric Stem Cell and Cellular Origin of Cancer.

Hata M, Hayakawa Y, Koike K.

Biomedicines. 2018 Oct 31;6(4). pii: E100. doi: 10.3390/biomedicines6040100. Review.

8.

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness.

Renz BW, Tanaka T, Sunagawa M, Takahashi R, Jiang Z, Macchini M, Dantes Z, Valenti G, White RA, Middelhoff MA, Ilmer M, Oberstein PE, Angele MK, Deng H, Hayakawa Y, Westphalen CB, Werner J, Remotti H, Reichert M, Tailor YH, Nagar K, Friedman RA, Iuga AC, Olive KP, Wang TC.

Cancer Discov. 2018 Nov;8(11):1458-1473. doi: 10.1158/2159-8290.CD-18-0046. Epub 2018 Sep 5.

PMID:
30185628
9.

Three types of metaplasia model through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium.

Kinoshita H, Hayakawa Y, Konishi M, Hata M, Tsuboi M, Hayata Y, Hikiba Y, Ihara S, Nakagawa H, Ikenoue T, Ushiku T, Fukayama M, Hirata Y, Koike K.

J Pathol. 2019 Jan;247(1):35-47. doi: 10.1002/path.5163. Epub 2018 Nov 27.

PMID:
30168144
10.

Role of warfarin as a predictor of recurrent bleeding after negative small-bowel capsule endoscopy.

Niikura R, Yamada A, Hirata Y, Hayakawa Y, Suzuki H, Yamamoto S, Fujishiro M, Koike K.

Gastrointest Endosc. 2018 Sep;88(3):574-574.e2. doi: 10.1016/j.gie.2018.04.2344. No abstract available.

PMID:
30115312
11.

The Tuft Cell-ILC2 Circuit Integrates Intestinal Defense and Homeostasis.

Hayakawa Y, Wang TC.

Cell. 2018 Jul 12;174(2):251-253. doi: 10.1016/j.cell.2018.06.037.

12.

Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease.

Ihara S, Hirata Y, Hikiba Y, Yamashita A, Tsuboi M, Hata M, Konishi M, Suzuki N, Sakitani K, Kinoshita H, Hayakawa Y, Nakagawa H, Ijichi H, Tateishi K, Koike K.

J Crohns Colitis. 2018 Nov 9;12(10):1219-1231. doi: 10.1093/ecco-jcc/jjy088.

PMID:
29917067
13.

Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.

Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, Kobayashi H, Putoczki TL, Hayakawa Y, Leedham SJ, Abud HE, Yilmaz ÖH, Marker J, Klebe S, Wirapati P, Mukherjee S, Tejpar S, Leggett BA, Whitehall VLJ, Worthley DL, Woods SL.

Gut. 2019 Apr;68(4):684-692. doi: 10.1136/gutjnl-2017-315920. Epub 2018 Apr 17.

14.

Efficacy of Vonoprazan for Gastroesophageal Reflux Symptoms in Patients with Proton Pump Inhibitor-resistant Non-erosive Reflux Disease.

Niikura R, Yamada A, Hirata Y, Hayakawa Y, Takahashi A, Shinozaki T, Takeuchi Y, Fujishiro M, Koike K.

Intern Med. 2018 Sep 1;57(17):2443-2450. doi: 10.2169/internalmedicine.0492-17. Epub 2018 Mar 30.

15.

Sessile serrated adenoma detection rate is correlated with adenoma detection rate.

Ohki D, Tsuji Y, Shinozaki T, Sakaguchi Y, Minatsuki C, Kinoshita H, Niimi K, Ono S, Hayakawa Y, Yoshida S, Yamada A, Kodashima S, Yamamichi N, Hirata Y, Ushiku T, Fujishiro M, Fukayama M, Koike K.

World J Gastrointest Oncol. 2018 Mar 15;10(3):82-90. doi: 10.4251/wjgo.v10.i3.82.

16.

Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer.

Niikura R, Hayakawa Y, Hirata Y, Konishi M, Suzuki N, Ihara S, Yamada A, Ushiku T, Fujishiro M, Fukayama M, Koike K.

Cancer Prev Res (Phila). 2018 May;11(5):279-286. doi: 10.1158/1940-6207.CAPR-17-0276. Epub 2018 Feb 16.

17.

Mature gastric chief cells are not required for the development of metaplasia.

Kinoshita H, Hayakawa Y, Niu Z, Konishi M, Hata M, Tsuboi M, Hayata Y, Hikiba Y, Ihara S, Nakagawa H, Hirata Y, Wang TC, Koike K.

Am J Physiol Gastrointest Liver Physiol. 2018 May 1;314(5):G583-G596. doi: 10.1152/ajpgi.00351.2017. Epub 2018 Jan 18.

18.

CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development.

Sakitani K, Hayakawa Y, Deng H, Ariyama H, Kinoshita H, Konishi M, Ono S, Suzuki N, Ihara S, Niu Z, Kim W, Tanaka T, Liu H, Chen X, Tailor Y, Fox JG, Konieczny SF, Onodera H, Sepulveda AR, Asfaha S, Hirata Y, Worthley DL, Koike K, Wang TC.

Oncotarget. 2017 Nov 10;8(67):111012-111025. doi: 10.18632/oncotarget.22451. eCollection 2017 Dec 19.

19.

Long-term proton pump inhibitor use is a risk factor of gastric cancer after treatment for Helicobacter pylori: a retrospective cohort analysis.

Niikura R, Hayakawa Y, Hirata Y, Yamada A, Fujishiro M, Koike K.

Gut. 2018 Oct;67(10):1908-1910. doi: 10.1136/gutjnl-2017-315710. Epub 2017 Dec 22. No abstract available.

PMID:
29273641
20.

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.

Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC.

Cancer Cell. 2018 Jan 8;33(1):75-90.e7. doi: 10.1016/j.ccell.2017.11.007. Epub 2017 Dec 14. Erratum in: Cancer Cell. 2018 Nov 12;34(5):863-867.

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