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Items: 1 to 20 of 28

1.

Development of novel double-decker microneedle patches for transcutaneous vaccine delivery.

Ono A, Azukizawa H, Ito S, Nakamura Y, Asada H, Quan YS, Kamiyama F, Katayama I, Hirobe S, Okada N.

Int J Pharm. 2017 Oct 30;532(1):374-383. doi: 10.1016/j.ijpharm.2017.08.110. Epub 2017 Aug 30.

PMID:
28855138
2.

Efficient Transdermal Delivery of Alendronate, a Nitrogen-Containing Bisphosphonate, Using Tip-Loaded Self-Dissolving Microneedle Arrays for the Treatment of Osteoporosis.

Katsumi H, Tanaka Y, Hitomi K, Liu S, Quan YS, Kamiyama F, Sakane T, Yamamoto A.

Pharmaceutics. 2017 Aug 17;9(3). pii: E29. doi: 10.3390/pharmaceutics9030029.

3.

Development of Novel Faster-Dissolving Microneedle Patches for Transcutaneous Vaccine Delivery.

Ono A, Ito S, Sakagami S, Asada H, Saito M, Quan YS, Kamiyama F, Hirobe S, Okada N.

Pharmaceutics. 2017 Aug 3;9(3). pii: E27. doi: 10.3390/pharmaceutics9030027.

4.

Permeation of sumatriptan succinate across human skin using multiple types of self-dissolving microneedle arrays fabricated from sodium hyaluronate.

Wu D, Katsumi H, Quan YS, Kamiyama F, Kusamori K, Sakane T, Yamamoto A.

J Drug Target. 2016 Sep;24(8):752-8. doi: 10.3109/1061186X.2016.1154565. Epub 2016 Mar 14.

PMID:
26878569
5.

Clinical study of a retinoic acid-loaded microneedle patch for seborrheic keratosis or senile lentigo.

Hirobe S, Otsuka R, Iioka H, Quan YS, Kamiyama F, Asada H, Okada N, Nakagawa S.

Life Sci. 2017 Jan 1;168:24-27. doi: 10.1016/j.lfs.2015.12.051. Epub 2016 Jan 3.

PMID:
26757104
6.

Development of a drug-coated microneedle array and its application for transdermal delivery of interferon alpha.

Kusamori K, Katsumi H, Sakai R, Hayashi R, Hirai Y, Tanaka Y, Hitomi K, Quan YS, Kamiyama F, Yamada K, Sumida S, Kishi K, Hashiba K, Sakane T, Yamamoto A.

Biofabrication. 2016 Jan 12;8(1):015006. doi: 10.1088/1758-5090/8/1/015006.

PMID:
26756832
7.

Improvement of Transdermal Delivery of Exendin-4 Using Novel Tip-Loaded Microneedle Arrays Fabricated from Hyaluronic Acid.

Liu S, Wu D, Quan YS, Kamiyama F, Kusamori K, Katsumi H, Sakane T, Yamamoto A.

Mol Pharm. 2016 Jan 4;13(1):272-9. doi: 10.1021/acs.molpharmaceut.5b00765. Epub 2015 Dec 18.

PMID:
26649921
8.

Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch.

Hirobe S, Azukizawa H, Hanafusa T, Matsuo K, Quan YS, Kamiyama F, Katayama I, Okada N, Nakagawa S.

Biomaterials. 2015 Jul;57:50-8. doi: 10.1016/j.biomaterials.2015.04.007. Epub 2015 Apr 24.

PMID:
25913250
9.

Improvement of transdermal delivery of sumatriptan succinate using a novel self-dissolving microneedle array fabricated from sodium hyaluronate in rats.

Wu D, Quan YS, Kamiyama F, Kusamori K, Katsumi H, Sakane T, Yamamoto A.

Biol Pharm Bull. 2015;38(3):365-73. doi: 10.1248/bpb.b14-00502.

10.

[Development of a novel transdermal delivery system of peptide and protein drugs using microneedle arrays].

Katsumi H, Quan YS, Kamiyama F, Kusamori K, Sakane T, Yamamoto A.

Yakugaku Zasshi. 2014;134(1):63-7. Review. Japanese.

11.

Vaccine efficacy of transcutaneous immunization with amyloid β using a dissolving microneedle array in a mouse model of Alzheimer's disease.

Matsuo K, Okamoto H, Kawai Y, Quan YS, Kamiyama F, Hirobe S, Okada N, Nakagawa S.

J Neuroimmunol. 2014 Jan 15;266(1-2):1-11. doi: 10.1016/j.jneuroim.2013.11.002. Epub 2013 Nov 11.

PMID:
24315156
12.

Transdermal delivery of relatively high molecular weight drugs using novel self-dissolving microneedle arrays fabricated from hyaluronic acid and their characteristics and safety after application to the skin.

Liu S, Jin MN, Quan YS, Kamiyama F, Kusamori K, Katsumi H, Sakane T, Yamamoto A.

Eur J Pharm Biopharm. 2014 Feb;86(2):267-76. doi: 10.1016/j.ejpb.2013.10.001. Epub 2013 Oct 9.

PMID:
24120887
13.

Development of a novel therapeutic approach using a retinoic acid-loaded microneedle patch for seborrheic keratosis treatment and safety study in humans.

Hiraishi Y, Hirobe S, Iioka H, Quan YS, Kamiyama F, Asada H, Okada N, Nakagawa S.

J Control Release. 2013 Oct 28;171(2):93-103. doi: 10.1016/j.jconrel.2013.06.008. Epub 2013 Jun 18.

PMID:
23791975
14.

Development and clinical study of a self-dissolving microneedle patch for transcutaneous immunization device.

Hirobe S, Azukizawa H, Matsuo K, Zhai Y, Quan YS, Kamiyama F, Suzuki H, Katayama I, Okada N, Nakagawa S.

Pharm Res. 2013 Oct;30(10):2664-74. doi: 10.1007/s11095-013-1092-6. Epub 2013 Jun 18.

PMID:
23775442
15.

Analysis of transcutaneous antigenic protein delivery by a hydrogel patch formulation.

Matsuo K, Ishii Y, Kawai Y, Saiba Y, Quan YS, Kamiyama F, Hirobe S, Okada N, Nakagawa S.

J Pharm Sci. 2013 Jun;102(6):1936-47. doi: 10.1002/jps.23540. Epub 2013 Apr 12.

PMID:
23585300
16.

Performance and characteristics evaluation of a sodium hyaluronate-based microneedle patch for a transcutaneous drug delivery system.

Hiraishi Y, Nakagawa T, Quan YS, Kamiyama F, Hirobe S, Okada N, Nakagawa S.

Int J Pharm. 2013 Jan 30;441(1-2):570-9. doi: 10.1016/j.ijpharm.2012.10.042. Epub 2012 Nov 5.

PMID:
23137695
17.

The development and characteristics of novel microneedle arrays fabricated from hyaluronic acid, and their application in the transdermal delivery of insulin.

Liu S, Jin MN, Quan YS, Kamiyama F, Katsumi H, Sakane T, Yamamoto A.

J Control Release. 2012 Aug 10;161(3):933-41. doi: 10.1016/j.jconrel.2012.05.030. Epub 2012 May 22.

PMID:
22634072
18.

Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza.

Matsuo K, Hirobe S, Yokota Y, Ayabe Y, Seto M, Quan YS, Kamiyama F, Tougan T, Horii T, Mukai Y, Okada N, Nakagawa S.

J Control Release. 2012 Jun 28;160(3):495-501. doi: 10.1016/j.jconrel.2012.04.001. Epub 2012 Apr 11. Erratum in: J Control Release. 2014 Jun 28;184:18-9.

PMID:
22516091
19.

Development of a novel self-dissolving microneedle array of alendronate, a nitrogen-containing bisphosphonate: evaluation of transdermal absorption, safety, and pharmacological effects after application in rats.

Katsumi H, Liu S, Tanaka Y, Hitomi K, Hayashi R, Hirai Y, Kusamori K, Quan YS, Kamiyama F, Sakane T, Yamamoto A.

J Pharm Sci. 2012 Sep;101(9):3230-8. doi: 10.1002/jps.23136. Epub 2012 Mar 29.

PMID:
22467424
20.

A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens.

Matsuo K, Yokota Y, Zhai Y, Quan YS, Kamiyama F, Mukai Y, Okada N, Nakagawa S.

J Control Release. 2012 Jul 10;161(1):10-7. doi: 10.1016/j.jconrel.2012.01.033. Epub 2012 Jan 28. Erratum in: J Control Release. 2014 Jun 28;184:9.

PMID:
22306332

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