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Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.

Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, Liu X, Xu L, Li X, Yu X, Sun B, Chen L.

Clin Sci (Lond). 2019 Aug 2;133(15):1705-1720. doi: 10.1042/CS20190585. Print 2019 Aug 15.


Low Long Noncoding RNA Growth Arrest-Specific Transcript 5 Expression in the Exosomes of Lung Cancer Cells Promotes Tumor Angiogenesis.

Cheng Y, Dai X, Yang T, Zhang N, Liu Z, Jiang Y.

J Oncol. 2019 May 2;2019:2476175. doi: 10.1155/2019/2476175. eCollection 2019.


Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial.

Mok TSK, Wu YL, Kudaba I, Kowalski DM, Cho BC, Turna HZ, Castro G Jr, Srimuninnimit V, Laktionov KK, Bondarenko I, Kubota K, Lubiniecki GM, Zhang J, Kush D, Lopes G; KEYNOTE-042 Investigators.

Lancet. 2019 May 4;393(10183):1819-1830. doi: 10.1016/S0140-6736(18)32409-7. Epub 2019 Apr 4.


Mitochondria and nucleus delivery of active form of 10-hydroxycamptothecin with dual shell to precisely treat colorectal cancer.

Li HQ, Ye WL, Huan ML, Cheng Y, Liu DZ, Cui H, Liu M, Zhang BL, Mei QB, Zhou SY.

Nanomedicine (Lond). 2019 Apr;14(8):1011-1032. doi: 10.2217/nnm-2018-0227. Epub 2019 Mar 29.


Inhibition of microRNA-124a attenuates non-alcoholic fatty liver disease through upregulation of adipose triglyceride lipase and the effect of liraglutide intervention.

Fang QH, Shen QL, Li JJ, Yang Y, Guo JJ, Cheng Y, Zhou HC, Niu WY, Chen LM, Li CJ, Sun B.

Hepatol Res. 2019 Jul;49(7):743-757. doi: 10.1111/hepr.13330. Epub 2019 Apr 17.


Pancreatic kallikrein protects against diabetic retinopathy in KK Cg-Ay/J and high-fat diet/streptozotocin-induced mouse models of type 2 diabetes.

Cheng Y, Yu X, Zhang J, Chang Y, Xue M, Li X, Lu Y, Li T, Meng Z, Su L, Sun B, Chen L.

Diabetologia. 2019 Jun;62(6):1074-1086. doi: 10.1007/s00125-019-4838-9. Epub 2019 Mar 5.


A more efficient ocular delivery system of triamcinolone acetonide as eye drop to the posterior segment of the eye.

Li J, Cheng T, Tian Q, Cheng Y, Zhao L, Zhang X, Qu Y.

Drug Deliv. 2019 Dec;26(1):188-198. doi: 10.1080/10717544.2019.1571122.


Prognostic factors of refractory NSCLC patients receiving anlotinib hydrochloride as the third- or further-line treatment.

Wang J, Zhao Y, Wang Q, Zhang L, Shi J, Wang Z, Cheng Y, He J, Shi Y, Yu H, Zhao Y, Chen W, Luo Y, Wang X, Nan K, Jin F, Dong J, Li B, Liu Z, Han B, Li K.

Cancer Biol Med. 2018 Nov;15(4):443-451. doi: 10.20892/j.issn.2095-3941.2018.0158.


Mitochondria-targeted cyclosporin A delivery system to treat myocardial ischemia reperfusion injury of rats.

Zhang CX, Cheng Y, Liu DZ, Liu M, Cui H, Zhang BL, Mei QB, Zhou SY.

J Nanobiotechnology. 2019 Jan 25;17(1):18. doi: 10.1186/s12951-019-0451-9.


Ferulic Acid Improves Depressive-Like Behavior in Prenatally-Stressed Offspring Rats via Anti-Inflammatory Activity and HPA Axis.

Zheng X, Cheng Y, Chen Y, Yue Y, Li Y, Xia S, Li Y, Deng H, Zhang J, Cao Y.

Int J Mol Sci. 2019 Jan 24;20(3). pii: E493. doi: 10.3390/ijms20030493.


Nivolumab Versus Docetaxel in a Predominantly Chinese Patient Population With Previously Treated Advanced NSCLC: CheckMate 078 Randomized Phase III Clinical Trial.

Wu YL, Lu S, Cheng Y, Zhou C, Wang J, Mok T, Zhang L, Tu HY, Wu L, Feng J, Zhang Y, Luft AV, Zhou J, Ma Z, Lu Y, Hu C, Shi Y, Baudelet C, Cai J, Chang J.

J Thorac Oncol. 2019 May;14(5):867-875. doi: 10.1016/j.jtho.2019.01.006. Epub 2019 Jan 17.


Mitochondria-targeted antioxidant delivery for precise treatment of myocardial ischemia-reperfusion injury through a multistage continuous targeted strategy.

Cheng Y, Liu DZ, Zhang CX, Cui H, Liu M, Zhang BL, Mei QB, Lu ZF, Zhou SY.

Nanomedicine. 2019 Feb;16:236-249. doi: 10.1016/j.nano.2018.12.014. Epub 2019 Jan 9.


TIMP-3 suppression induces choroidal neovascularization by moderating the polarization of macrophages in age-related macular degeneration.

Cheng Y, Cheng T, Qu Y.

Mol Immunol. 2019 Feb;106:119-126. doi: 10.1016/j.molimm.2018.12.026. Epub 2018 Dec 27.


[Disparities of EGFR mutations between Biopsy and Rebiopsy in Non-small Cell Lung Cancer Patients].

Li H, Yan S, Liu X, Liu Y, Ma L, Wang Y, Liu Y, Cheng Y.

Zhongguo Fei Ai Za Zhi. 2018 Nov 20;21(11):821-827. doi: 10.3779/j.issn.1009-3419.2018.11.03. Chinese.


Aquaporins Alteration Profiles Revealed Different Actions of Senna, Sennosides, and Sennoside A in Diarrhea-Rats.

Cao Y, He Y, Wei C, Li J, Qu L, Zhang H, Cheng Y, Qiao B.

Int J Mol Sci. 2018 Oct 17;19(10). pii: E3210. doi: 10.3390/ijms19103210.


Pembrolizumab plus Chemotherapy for Squamous Non-Small-Cell Lung Cancer.

Paz-Ares L, Luft A, Vicente D, Tafreshi A, Gümüş M, Mazières J, Hermes B, Çay Şenler F, Csőszi T, Fülöp A, Rodríguez-Cid J, Wilson J, Sugawara S, Kato T, Lee KH, Cheng Y, Novello S, Halmos B, Li X, Lubiniecki GM, Piperdi B, Kowalski DM; KEYNOTE-407 Investigators.

N Engl J Med. 2018 Nov 22;379(21):2040-2051. doi: 10.1056/NEJMoa1810865. Epub 2018 Sep 25.


Triptolide Attenuates Renal Tubular Epithelial-mesenchymal Transition Via the MiR-188-5p-mediated PI3K/AKT Pathway in Diabetic Kidney Disease.

Xue M, Cheng Y, Han F, Chang Y, Yang Y, Li X, Chen L, Lu Y, Sun B, Chen L.

Int J Biol Sci. 2018 Sep 7;14(11):1545-1557. doi: 10.7150/ijbs.24032. eCollection 2018.


[Advances on Recognizing and Managing Tumor Heterogeneity].

Zhong R, Li H, Zhang S, Liu J, Cheng Y.

Zhongguo Fei Ai Za Zhi. 2018 Sep 20;21(9):712-718. doi: 10.3779/j.issn.1009-3419.2018.09.11. Review. Chinese.


Thymosin β4 Prevents Oxidative Stress, Inflammation, and Fibrosis in Ethanol- and LPS-Induced Liver Injury in Mice.

Shah R, Reyes-Gordillo K, Cheng Y, Varatharajalu R, Ibrahim J, Lakshman MR.

Oxid Med Cell Longev. 2018 Jul 11;2018:9630175. doi: 10.1155/2018/9630175. eCollection 2018.


The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome.

Dong Y, Cheng Y, Hou Q, Wu J, Li D, Tian H.

Oxid Med Cell Longev. 2018 Jul 4;2018:3920147. doi: 10.1155/2018/3920147. eCollection 2018.

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