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Items: 1 to 20 of 41


Digital Receptor Occupancy Assay in Quantifying On- and Off-Target Binding Affinities of Therapeutic Antibodies.

Chou CK, Liu YL, Chen YI, Huang PJ, Tsou PH, Chen CT, Lee HH, Wang YN, Hsu JL, Lee JF, Yankeelov TE, Kameoka J, Yeh HC, Hung MC.

ACS Sens. 2020 Feb 28;5(2):296-302. doi: 10.1021/acssensors.9b01736. Epub 2020 Feb 19.


Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer.

Liu YL, Horning AM, Lieberman B, Kim M, Lin CK, Hung CN, Chou CW, Wang CM, Lin CL, Kirma NB, Liss MA, Vasisht R, Perillo EP, Blocher K, Horng H, Taverna JA, Ruan J, Yankeelov TE, Dunn AK, Huang TH, Yeh HC, Chen CL.

Cancers (Basel). 2019 Dec 1;11(12). pii: E1910. doi: 10.3390/cancers11121910.


Measuring DNA Hybridization Kinetics in Live Cells Using a Time-Resolved 3D Single-Molecule Tracking Method.

Chen YI, Chang YJ, Nguyen TD, Liu C, Phillion S, Kuo YA, Vu HT, Liu A, Liu YL, Hong S, Ren P, Yankeelov TE, Yeh HC.

J Am Chem Soc. 2019 Oct 9;141(40):15747-15750. doi: 10.1021/jacs.9b08036. Epub 2019 Sep 26.


Assessing metastatic potential of breast cancer cells based on EGFR dynamics.

Liu YL, Chou CK, Kim M, Vasisht R, Kuo YA, Ang P, Liu C, Perillo EP, Chen YA, Blocher K, Horng H, Chen YI, Nguyen DT, Yankeelov TE, Hung MC, Dunn AK, Yeh HC.

Sci Rep. 2019 Mar 4;9(1):3395. doi: 10.1038/s41598-018-37625-0.


Polymer dots enable deep in vivo multiphoton fluorescence imaging of microvasculature.

Hassan AM, Wu X, Jarrett JW, Xu S, Yu J, Miller DR, Perillo EP, Liu YL, Chiu DT, Yeh HC, Dunn AK.

Biomed Opt Express. 2019 Jan 15;10(2):584-599. doi: 10.1364/BOE.10.000584. eCollection 2019 Feb 1.


Improving NanoCluster Beacon performance by blocking the unlabeled NC probes.

Chen YA, Vu HT, Liu YL, Chen YI, Nguyen TD, Kuo YA, Hong S, Chen YA, Carnahan S, Petty JT, Yeh HC.

Chem Commun (Camb). 2019 Jan 3;55(4):462-465. doi: 10.1039/c8cc08291j.


A flow-proteometric platform for analyzing protein concentration (FAP): Proof of concept for quantification of PD-L1 protein in cells and tissues.

Chou CK, Huang PJ, Tsou PH, Wei Y, Lee HH, Wang YN, Liu YL, Shi C, Yeh HC, Kameoka J, Hung MC.

Biosens Bioelectron. 2018 Oct 15;117:97-103. doi: 10.1016/j.bios.2018.05.053. Epub 2018 May 29.


Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.

Li CW, Lim SO, Chung EM, Kim YS, Park AH, Yao J, Cha JH, Xia W, Chan LC, Kim T, Chang SS, Lee HH, Chou CK, Liu YL, Yeh HC, Perillo EP, Dunn AK, Kuo CW, Khoo KH, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Huang TH, Sahin AA, Hortobagyi GN, Yoo SS, Hung MC.

Cancer Cell. 2018 Feb 12;33(2):187-201.e10. doi: 10.1016/j.ccell.2018.01.009.


A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report.

Yang CC, Wang WC, Yeh TH, Chen TH, Liu YL, Lu MK, Lu CS, Tsai CH.

Clin Neurol Neurosurg. 2018 Feb;165:21-23. doi: 10.1016/j.clineuro.2017.12.018. Epub 2017 Dec 26.


Renal function is associated with 1-month and 1-year mortality in patients with ischemic stroke.

Wang IK, Liu CH, Yen TH, Jeng JS, Sung SF, Huang PH, Li JY, Sun Y, Wei CY, Lien LM, Tsai IJ, Sung FC, Hsu CY; Taiwan Stroke Registry Investigators.

Atherosclerosis. 2018 Feb;269:288-293. doi: 10.1016/j.atherosclerosis.2017.11.029. Epub 2017 Dec 11.


Syndecan-1 in mechanosensing of nanotopological cues in engineered materials.

Le V, Lee J, Chaterji S, Spencer A, Liu YL, Kim P, Yeh HC, Kim DH, Baker AB.

Biomaterials. 2018 Feb;155:13-24. doi: 10.1016/j.biomaterials.2017.11.007. Epub 2017 Nov 9.


LNA Thymidine Monomer Enables Differentiation of the Four Single-Nucleotide Variants by Melting Temperature.

Obliosca JM, Cheng SY, Chen YA, Llanos MF, Liu YL, Imphean DM, Bell DR, Petty JT, Ren P, Yeh HC.

J Am Chem Soc. 2017 May 24;139(20):7110-7116. doi: 10.1021/jacs.7b03395. Epub 2017 May 9.


3D single-molecule tracking enables direct hybridization kinetics measurement in solution.

Liu C, Obliosca JM, Liu YL, Chen YA, Jiang N, Yeh HC.

Nanoscale. 2017 May 4;9(17):5664-5670. doi: 10.1039/c7nr01369h.


Cholesterol Levels Are Associated with 30-day Mortality from Ischemic Stroke in Dialysis Patients.

Wang IK, Liu CH, Yen TH, Jeng JS, Hsu SP, Chen CH, Lien LM, Lin RT, Chen AC, Lin HJ, Chi HY, Lai TC, Sun Y, Lee SP, Sung SF, Chen PL, Lee JT, Chiang TR, Lin SK, Muo CH, Ma H, Wen CP, Sung FC, Hsu CY; Taiwan Stroke Registry Investigators.

J Stroke Cerebrovasc Dis. 2017 Jun;26(6):1349-1356. doi: 10.1016/j.jstrokecerebrovasdis.2017.02.007. Epub 2017 Mar 21.


Two-color multiphoton in vivo imaging with a femtosecond diamond Raman laser.

Perillo EP, Jarrett JW, Liu YL, Hassan A, Fernée DC, Goldak JR, Bonteanu A, Spence DJ, Yeh HC, Dunn AK.

Light Sci Appl. 2017;6. pii: e17095. doi: 10.1038/lsa.2017.95. Epub 2017 Nov 17.


Segmentation of 3D Trajectories Acquired by TSUNAMI Microscope: An Application to EGFR Trafficking.

Liu YL, Perillo EP, Liu C, Yu P, Chou CK, Hung MC, Dunn AK, Yeh HC.

Biophys J. 2016 Nov 15;111(10):2214-2227. doi: 10.1016/j.bpj.2016.09.041.


Single-Molecule Tracking and Its Application in Biomolecular Binding Detection.

Liu C, Liu YL, Perillo EP, Dunn AK, Yeh HC.

IEEE J Sel Top Quantum Electron. 2016 Jul-Aug;22(4). pii: 6804013. Epub 2016 May 17.


Expandable Scaffold Improves Integration of Tissue-Engineered Cartilage: An In Vivo Study in a Rabbit Model.

Wang CC, Yang KC, Lin KH, Liu YL, Yang YT, Kuo TF, Chen IH.

Tissue Eng Part A. 2016 Jun;22(11-12):873-84. doi: 10.1089/ten.TEA.2015.0510.


NanoCluster Beacons Enable Detection of a Single N⁶-Methyladenine.

Chen YA, Obliosca JM, Liu YL, Liu C, Gwozdz ML, Yeh HC.

J Am Chem Soc. 2015 Aug 26;137(33):10476-9. doi: 10.1021/jacs.5b06038. Epub 2015 Aug 14.


Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination.

Perillo EP, Liu YL, Huynh K, Liu C, Chou CK, Hung MC, Yeh HC, Dunn AK.

Nat Commun. 2015 Jul 29;6:7874. doi: 10.1038/ncomms8874.

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