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Items: 1 to 20 of 217


Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models.

Peng X, Hou P, Chen Y, Dai Y, Ji Y, Shen Y, Su Y, Liu B, Wang Y, Sun D, Jiang Y, Zha C, Xie Z, Ding J, Geng M, Ai J.

J Exp Clin Cancer Res. 2019 Aug 22;38(1):372. doi: 10.1186/s13046-019-1357-y.


Overexpression of the Oral Mucosa-Specific microRNA-31 Promotes Skin Wound Closure.

Chen L, Simões A, Chen Z, Zhao Y, Wu X, Dai Y, DiPietro LA, Zhou X.

Int J Mol Sci. 2019 Jul 27;20(15). pii: E3679. doi: 10.3390/ijms20153679.


Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.

Wang Y, Dai Y, Wu X, Li F, Liu B, Li C, Liu Q, Zhou Y, Wang B, Zhu M, Cui R, Tan X, Xiong Z, Liu J, Tan M, Xu Y, Geng M, Jiang H, Liu H, Ai J, Zheng M.

J Med Chem. 2019 Aug 22;62(16):7473-7488. doi: 10.1021/acs.jmedchem.9b00510. Epub 2019 Aug 9.


Prevalence of intestinal helminth infections in Jiangsu Province, eastern China; a cross-sectional survey conducted in 2015.

Dai Y, Xu X, Liu J, Jin X, Shen M, Wang X, Cao J, Yang H.

BMC Infect Dis. 2019 Jul 10;19(1):604. doi: 10.1186/s12879-019-4264-0.


Lipoprotein (a) interactions with cholesterol-containing lipids on angiographic coronary collateralization in type 2 diabetic patients with chronic total occlusion.

Shen Y, Chen S, Dai Y, Wang XQ, Zhang RY, Yang ZK, Hu J, Lu L, Ding FH, Shen WF.

Cardiovasc Diabetol. 2019 Jun 24;18(1):82. doi: 10.1186/s12933-019-0888-z.


Absence of complement component 3 does not prevent classical pathway-mediated hemolysis.

Zhang L, Dai Y, Huang P, Saunders TL, Fox DA, Xu J, Lin F.

Blood Adv. 2019 Jun 25;3(12):1808-1814. doi: 10.1182/bloodadvances.2019031591.


Differential microRNA profile underlies the divergent healing responses in skin and oral mucosal wounds.

Simões A, Chen L, Chen Z, Zhao Y, Gao S, Marucha PT, Dai Y, DiPietro LA, Zhou X.

Sci Rep. 2019 May 9;9(1):7160. doi: 10.1038/s41598-019-43682-w.


Circ_0005075 promotes hepatocellular carcinoma progression by suppression of microRNA-335.

Yang X, Song H, Zi Z, Kou J, Chen S, Dai Y, Wang J, Yuan L, Gao K.

J Cell Physiol. 2019 May 3. doi: 10.1002/jcp.28757. [Epub ahead of print]


Tanshinone IIA protects against lipopolysaccharide-induced lung injury through targeting Sirt1.

Quan M, Lv Y, Dai Y, Qi B, Fu L, Chen X, Qian Y.

J Pharm Pharmacol. 2019 Jul;71(7):1142-1151. doi: 10.1111/jphp.13087. Epub 2019 Mar 13.


Secretory vimentin is associated with coronary artery disease in patients and induces atherogenesis in ApoE-/- mice.

Gong DH, Dai Y, Chen S, Wang XQ, Yan XX, Shen Y, Liu J, Yang ZK, Hu J, Yu LJ, Liu LL, Zhang RY, Shen WF, Chen QJ, Ding FH, Lu L.

Int J Cardiol. 2019 May 15;283:9-16. doi: 10.1016/j.ijcard.2019.02.032. Epub 2019 Feb 16.


Pak1 gene functioned differentially in different BCR-ABL subtypes in leukemiagenesis and treatment response through STAT5 pathway.

Yuanxin Y, Yanhong Z, Qin Z, Sishi T, Yang D, Yi Z, Minjin W, Juan Z, Xiaojun L, Lanlan W, Binwu Y.

Leuk Res. 2019 Apr;79:6-16. doi: 10.1016/j.leukres.2019.01.012. Epub 2019 Jan 24.


Utilizing longitudinal microbiome taxonomic profiles to predict food allergy via Long Short-Term Memory networks.

Metwally AA, Yu PS, Reiman D, Dai Y, Finn PW, Perkins DL.

PLoS Comput Biol. 2019 Feb 4;15(2):e1006693. doi: 10.1371/journal.pcbi.1006693. eCollection 2019 Feb.


Discovery of a potent tyrosine kinase AXL inhibitor bearing the 3-((2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)amino)pyrazine core.

Wang Y, Xing L, Ji Y, Ye J, Dai Y, Gu W, Ai J, Song Z.

Bioorg Med Chem Lett. 2019 Mar 15;29(6):836-838. doi: 10.1016/j.bmcl.2019.01.018. Epub 2019 Jan 21.


Decreased circulating catestatin levels are associated with coronary artery disease: The emerging anti-inflammatory role.

Chen Y, Wang X, Yang C, Su X, Yang W, Dai Y, Han H, Jiang J, Lu L, Wang H, Chen Q, Jin W.

Atherosclerosis. 2019 Feb;281:78-88. doi: 10.1016/j.atherosclerosis.2018.12.025. Epub 2018 Dec 24.


Final results of the phase 1/2, open-label clinical study of intravenous recombinant human N-acetyl-α-d-glucosaminidase (SBC-103) in children with mucopolysaccharidosis IIIB.

Whitley CB, Vijay S, Yao B, Pineda M, Parker GJM, Rojas-Caro S, Zhang X, Dai Y, Cinar A, Bubb G, Patki KC, Escolar ML.

Mol Genet Metab. 2019 Feb;126(2):131-138. doi: 10.1016/j.ymgme.2018.12.003. Epub 2018 Dec 6.


MeDEStrand: an improved method to infer genome-wide absolute methylation levels from DNA enrichment data.

Xu J, Liu S, Yin P, Bulun S, Dai Y.

BMC Bioinformatics. 2018 Dec 22;19(1):540. doi: 10.1186/s12859-018-2574-7.


Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma.

Wang Q, Dai Y, Ji Y, Shi H, Guo Z, Chen D, Chen Y, Peng X, Gao Y, Wang X, Chen L, Jiang Y, Geng M, Shen J, Ai J, Xiong B.

Eur J Med Chem. 2019 Feb 1;163:671-689. doi: 10.1016/j.ejmech.2018.12.015. Epub 2018 Dec 7.


[Current status of chronic filariasis in Jiangsu Province].

Fan-Zhen M, Xiang-Zhen X, Xiao-Lin J, Bi-Xian N, Yang D.

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2018 Nov 12;30(5):563-566. doi: 10.16250/j.32.1374.2018215. Chinese.


Asiatic acid protests against myocardial ischemia/reperfusion injury via modulation of glycometabolism in rat cardiomyocyte.

Dai Y, Wang Z, Quan M, Lv Y, Li Y, Xin HB, Qian Y.

Drug Des Devel Ther. 2018 Oct 25;12:3573-3582. doi: 10.2147/DDDT.S175116. eCollection 2018.


Molecular Evidence for the Fitness of Cotton Aphid, Aphis gossypii in Response to Elevated CO2 From the Perspective of Feeding Behavior Analysis.

Jiang S, Dai Y, Lu Y, Fan S, Liu Y, Bodlah MA, Parajulee MN, Chen F.

Front Physiol. 2018 Nov 12;9:1444. doi: 10.3389/fphys.2018.01444. eCollection 2018.

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