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Items: 1 to 20 of 36


Synthesis and Biological Evaluation of Quinoline Derivatives as a Novel Class of Broad-Spectrum Antibacterial Agents.

Fu HG, Li ZW, Hu XX, Si SY, You XF, Tang S, Wang YX, Song DQ.

Molecules. 2019 Feb 2;24(3). pii: E548. doi: 10.3390/molecules24030548.


Synthesis and antibacterial evaluation of 13-substituted cycloberberine derivatives as a novel class of anti-MRSA agents.

Fan TY, Wang YX, Tang S, Hu XX, Zen QX, Pang J, Yang YS, You XF, Song DQ.

Eur J Med Chem. 2018 Sep 5;157:877-886. doi: 10.1016/j.ejmech.2018.08.050. Epub 2018 Aug 18.


Synthesis and Evolution of Berberine Derivatives as a New Class of Antiviral Agents against Enterovirus 71 through the MEK/ERK Pathway and Autophagy.

Wang YX, Yang L, Wang HQ, Zhao XQ, Liu T, Li YH, Zeng QX, Li YH, Song DQ.

Molecules. 2018 Aug 20;23(8). pii: E2084. doi: 10.3390/molecules23082084.


Synthesis and Biological Evaluation of 12N-substituted Tricyclic Matrinic Derivatives as a Novel Family of Anti-Influenza Agents.

Tang S, Li YH, Cheng XY, Yin JQ, Li YH, Song DQ, Wang YX, Liu ZD.

Med Chem. 2018;14(8):764-772. doi: 10.2174/1573406414666180222093033.


Synthesis and biological evaluation of new berberine derivatives as cancer immunotherapy agents through targeting IDO1.

Wang YX, Pang WQ, Zeng QX, Deng ZS, Fan TY, Jiang JD, Deng HB, Song DQ.

Eur J Med Chem. 2018 Jan 1;143:1858-1868. doi: 10.1016/j.ejmech.2017.10.078. Epub 2017 Nov 11.


Synthesis and biological evaluation of tricyclic matrinic derivatives as a class of novel anti-HCV agents.

Tang S, Peng ZG, Li YH, Zhang X, Fan TY, Jiang JD, Wang YX, Song DQ.

Chem Cent J. 2017 Sep 29;11(1):94. doi: 10.1186/s13065-017-0327-8.


Synthesis and Identification of Novel Berberine Derivatives as Potent Inhibitors against TNF-α-Induced NF-κB Activation.

Wang YX, Liu L, Zeng QX, Fan TY, Jiang JD, Deng HB, Song DQ.

Molecules. 2017 Jul 27;22(8). pii: E1257. doi: 10.3390/molecules22081257.


How can tricyclic sophoridinic derivatives be used as autophagy inhibitors for cancer treatments?

Wang YX, Liu ZD, Bi CW, Liu L, Deng HB, Song DQ.

Future Med Chem. 2017 Jun;9(9):835-837. doi: 10.4155/fmc-2017-0081. Epub 2017 Jun 21. No abstract available.


Evolution of matrinic ethanol derivatives as anti-HCV agents from matrine skeleton.

Li YH, Wu ZY, Tang S, Zhang X, Wang YX, Jiang JD, Peng ZG, Song DQ.

Bioorg Med Chem Lett. 2017 May 1;27(9):1962-1966. doi: 10.1016/j.bmcl.2017.03.025. Epub 2017 Mar 11.


Novel 12N-substituted matrinanes as potential anti-coxsackievirus agents.

Li YH, Tang S, Li YH, Cheng XY, Zhang X, Wang YX, Su F, Song DQ.

Bioorg Med Chem Lett. 2017 Feb 15;27(4):829-833. doi: 10.1016/j.bmcl.2017.01.022. Epub 2017 Jan 10.


Synthesis and evaluation of halogenated 12N-sulfonyl matrinic butanes as potential anti-coxsackievirus agents.

Cheng XY, Li YH, Tang S, Zhang X, Wang YX, Wang SG, Jiang JD, Li YH, Song DQ.

Eur J Med Chem. 2017 Jan 27;126:133-142. doi: 10.1016/j.ejmech.2016.09.097. Epub 2016 Sep 30.


CD36 is a co-receptor for hepatitis C virus E1 protein attachment.

Cheng JJ, Li JR, Huang MH, Ma LL, Wu ZY, Jiang CC, Li WJ, Li YH, Han YX, Li H, Chen JH, Wang YX, Song DQ, Peng ZG, Jiang JD.

Sci Rep. 2016 Feb 22;6:21808. doi: 10.1038/srep21808.


Design, synthesis and biological evaluation of monobactams as antibacterial agents against gram-negative bacteria.

Fu HG, Hu XX, Li CR, Li YH, Wang YX, Jiang JD, Bi CW, Tang S, You XF, Song DQ.

Eur J Med Chem. 2016 Mar 3;110:151-63. doi: 10.1016/j.ejmech.2016.01.024. Epub 2016 Jan 20.


The F-box family genes as key elements in response to salt, heavy mental, and drought stresses in Medicago truncatula.

Song JB, Wang YX, Li HB, Li BW, Zhou ZS, Gao S, Yang ZM.

Funct Integr Genomics. 2015 Jul;15(4):495-507. doi: 10.1007/s10142-015-0438-z. Epub 2015 Apr 16.


[Treatment of comminuted fracture of tibial plateau with ni-ti shape memory alloy bow-teeth screws combined with locking plate internal fixation].

Wang YX, Zhang YT, Tang Y, Zhao X, Fu QG, Zhang X, Zhang CC.

Zhongguo Gu Shang. 2013 Jul;26(7):601-4. Chinese.


Discovery, synthesis and biological evaluation of cycloprotoberberine derivatives as potential antitumor agents.

Li YB, Zhao WL, Wang YX, Zhang CX, Jiang JD, Bi CW, Tang S, Chen RX, Shao RG, Song DQ.

Eur J Med Chem. 2013 Oct;68:463-72. doi: 10.1016/j.ejmech.2013.07.026. Epub 2013 Aug 11.


Tetrandrine potentiates the hypoglycemic efficacy of berberine by inhibiting P-glycoprotein function.

Shan YQ, Zhu YP, Pang J, Wang YX, Song DQ, Kong WJ, Jiang JD.

Biol Pharm Bull. 2013;36(10):1562-9. Epub 2013 Aug 8.


Synthesis and biological evaluation of N-substituted sophocarpinic acid derivatives as coxsackievirus B3 inhibitors.

Gao LM, Tang S, Wang YX, Gao RM, Zhang X, Peng ZG, Li JR, Jiang JD, Li YH, Song DQ.

ChemMedChem. 2013 Sep;8(9):1545-53. doi: 10.1002/cmdc.201300224. Epub 2013 Jul 23.


Synthesis and structure-activity relationship of 8-substituted protoberberine derivatives as a novel class of antitubercular agents.

Li YH, Fu HG, Su F, Gao LM, Tang S, Bi CW, Li YH, Wang YX, Song DQ.

Chem Cent J. 2013 Jul 10;7(1):117. doi: 10.1186/1752-153X-7-117.


N-substituted benzyl matrinic acid derivatives inhibit hepatitis C virus (HCV) replication through down-regulating host heat-stress cognate 70 (Hsc70) expression.

Du NN, Peng ZG, Bi CW, Tang S, Li YH, Li JR, Zhu YP, Zhang JP, Wang YX, Jiang JD, Song DQ.

PLoS One. 2013;8(3):e58675. doi: 10.1371/journal.pone.0058675. Epub 2013 Mar 14.

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