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Items: 1 to 20 of 24


DNA stable-isotope probing delineates carbon flows from rice residues into soil microbial communities depending on fertilization.

Kong Y, Kuzyakov Y, Ruan Y, Zhang J, Wang T, Wang M, Guo S, Shen Q, Ling N.

Appl Environ Microbiol. 2020 Jan 17. pii: AEM.02151-19. doi: 10.1128/AEM.02151-19. [Epub ahead of print]


Marine Toxins Detection by Biosensors Based on Aptamers.

Ye W, Liu T, Zhang W, Zhu M, Liu Z, Kong Y, Liu S.

Toxins (Basel). 2019 Dec 18;12(1). pii: E1. doi: 10.3390/toxins12010001. Review.


Disclosure of the Molecular Mechanism of Wheat Leaf Spot Disease Caused by Bipolaris sorokiniana through Comparative Transcriptome and Metabolomics Analysis.

Ye W, Liu T, Zhang W, Li S, Zhu M, Li H, Kong Y, Xu L.

Int J Mol Sci. 2019 Dec 3;20(23). pii: E6090. doi: 10.3390/ijms20236090.


Long-term fertilization regimes change soil nitrification potential by impacting active autotrophic ammonia oxidizers and nitrite oxidizers as assessed by DNA stable isotope probing.

Kong Y, Ling N, Xue C, Chen H, Ruan Y, Guo J, Zhu C, Wang M, Shen Q, Guo S.

Environ Microbiol. 2019 Apr;21(4):1224-1240. doi: 10.1111/1462-2920.14553. Epub 2019 Mar 14.


Improving rice population productivity by reducing nitrogen rate and increasing plant density.

Tian G, Gao L, Kong Y, Hu X, Xie K, Zhang R, Ling N, Shen Q, Guo S.

PLoS One. 2017 Aug 2;12(8):e0182310. doi: 10.1371/journal.pone.0182310. eCollection 2017.


Development of a novel near-infrared fluorescent theranostic combretastain A-4 analogue, YK-5-252, to target triple negative breast cancer.

Kong Y, Smith J, Li K, Cui J, Han J, Hou S, Brown ML.

Bioorg Med Chem. 2017 Apr 1;25(7):2226-2233. doi: 10.1016/j.bmc.2017.02.046. Epub 2017 Feb 24.


Disruption of STAT3-DNMT1 interaction by SH-I-14 induces re-expression of tumor suppressor genes and inhibits growth of triple-negative breast tumor.

Kang HJ, Yi YW, Hou SJ, Kim HJ, Kong Y, Bae I, Brown ML.

Oncotarget. 2015 May 9;8(48):83457-83468. doi: 10.18632/oncotarget.4054. eCollection 2017 Oct 13.


Total Synthesis of 7-Hydroxymurrayazolinine, Murrayamine D, and Mahanine via m-Nitro Group Activated Pyran Annulation.

Hou S, Liu Y, Kong Y, Brown ML.

Org Lett. 2015 May 15;17(10):2298-301. doi: 10.1021/acs.orglett.5b00422. Epub 2015 Apr 28.


Preclinical studies of the potent and selective nicotinic α4β2 receptor ligand VMY-2-95.

Kong H, Song JK, Yenugonda VM, Zhang L, Shuo T, Cheema AK, Kong Y, Du GH, Brown ML.

Mol Pharm. 2015 Feb 2;12(2):393-402. doi: 10.1021/mp5003569. Epub 2015 Jan 20.


A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model.

Rahim S, Minas T, Hong SH, Justvig S, Çelik H, Kont YS, Han J, Kallarakal AT, Kong Y, Rudek MA, Brown ML, Kallakury B, Toretsky JA, Üren A.

PLoS One. 2014 Dec 5;9(12):e114260. doi: 10.1371/journal.pone.0114260. eCollection 2014.


Synthesis and structure-activity relationship studies of small molecule disruptors of EWS-FLI1 interactions in Ewing's sarcoma.

Tosso PN, Kong Y, Scher L, Cummins R, Schneider J, Rahim S, Holman KT, Toretsky J, Wang K, Üren A, Brown ML.

J Med Chem. 2014 Dec 26;57(24):10290-303. doi: 10.1021/jm501372p. Epub 2014 Dec 12.


Novel carbazole inhibits phospho-STAT3 through induction of protein-tyrosine phosphatase PTPN6.

Hou S, Yi YW, Kang HJ, Zhang L, Kim HJ, Kong Y, Liu Y, Wang K, Kong HS, Grindrod S, Bae I, Brown ML.

J Med Chem. 2014 Aug 14;57(15):6342-53. doi: 10.1021/jm4018042. Epub 2014 Aug 4.


Preclinical studies of YK-4-272, an inhibitor of class II histone deacetylases by disruption of nucleocytoplasmic shuttling.

Kong HS, Tian S, Kong Y, Du G, Zhang L, Jung M, Dritschilo A, Brown ML.

Pharm Res. 2012 Dec;29(12):3373-83. doi: 10.1007/s11095-012-0832-3. Epub 2012 Jul 27.


Trans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cells.

Yenugonda VM, Kong Y, Deb TB, Yang Y, Riggins RB, Brown ML.

Cancer Biol Ther. 2012 Aug;13(10):925-34. doi: 10.4161/cbt.20845. Epub 2012 Aug 1.


Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1.

Barber-Rotenberg JS, Selvanathan SP, Kong Y, Erkizan HV, Snyder TM, Hong SP, Kobs CL, South NL, Summer S, Monroe PJ, Chruszcz M, Dobrev V, Tosso PN, Scher LJ, Minor W, Brown ML, Metallo SJ, Üren A, Toretsky JA.

Oncotarget. 2012 Feb;3(2):172-82.


Asymmetric synthesis and evaluation of a hydroxyphenylamide voltage-gated sodium channel blocker in human prostate cancer xenografts.

Davis GC, Kong Y, Paige M, Li Z, Merrick EC, Hansen T, Suy S, Wang K, Dakshanamurthy S, Cordova A, McManus OB, Williams BS, Chruszcz M, Minor W, Patel MK, Brown ML.

Bioorg Med Chem. 2012 Mar 15;20(6):2180-8. doi: 10.1016/j.bmc.2011.08.061. Epub 2011 Sep 1.


Histone deacetylase cytoplasmic trapping by a novel fluorescent HDAC inhibitor.

Kong Y, Jung M, Wang K, Grindrod S, Velena A, Lee SA, Dakshanamurthy S, Yang Y, Miessau M, Zheng C, Dritschilo A, Brown ML.

Mol Cancer Ther. 2011 Sep;10(9):1591-9. doi: 10.1158/1535-7163.MCT-10-0779. Epub 2011 Jun 22.


YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.

Rahim S, Beauchamp EM, Kong Y, Brown ML, Toretsky JA, Üren A.

PLoS One. 2011 Apr 29;6(4):e19343. doi: 10.1371/journal.pone.0019343.


High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.

Awad O, Yustein JT, Shah P, Gul N, Katuri V, O'Neill A, Kong Y, Brown ML, Toretsky JA, Loeb DM.

PLoS One. 2010 Nov 11;5(11):e13943. doi: 10.1371/journal.pone.0013943.

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