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Items: 1 to 20 of 54


Overexpression of a Neuronal Type Adenylyl Cyclase (Type 8) in Sinoatrial Node Markedly Impacts Heart Rate and Rhythm.

Moen JM, Matt MG, Ramirez C, Tarasov KV, Chakir K, Tarasova YS, Lukyanenko Y, Tsutsui K, Monfredi O, Morrell CH, Tagirova S, Yaniv Y, Huynh T, Pacak K, Ahmet I, Lakatta EG.

Front Neurosci. 2019 Jun 18;13:615. doi: 10.3389/fnins.2019.00615. eCollection 2019.


Eliminating contraction during culture maintains global and local Ca2+ dynamics in cultured rabbit pacemaker cells.

Segal S, Kirschner Peretz N, Arbel-Ganon L, Liang J, Li L, Marbach D, Yang D, Wang SQ, Yaniv Y.

Cell Calcium. 2019 Mar;78:35-47. doi: 10.1016/j.ceca.2018.12.008. Epub 2018 Dec 18.


PhysioZoo: A Novel Open Access Platform for Heart Rate Variability Analysis of Mammalian Electrocardiographic Data.

Behar JA, Rosenberg AA, Weiser-Bitoun I, Shemla O, Alexandrovich A, Konyukhov E, Yaniv Y.

Front Physiol. 2018 Oct 4;9:1390. doi: 10.3389/fphys.2018.01390. eCollection 2018.


Bioenergetic Feedback between Heart Cell Contractile Machinery and Mitochondrial 3D Deformations.

Kamoun D, Behar J, Leichner JM, Yaniv Y.

Biophys J. 2018 Oct 16;115(8):1603-1613. doi: 10.1016/j.bpj.2018.08.039. Epub 2018 Sep 6.


An SVM approach for identifying atrial fibrillation.

Gliner V, Yaniv Y.

Physiol Meas. 2018 Sep 27;39(9):094007. doi: 10.1088/1361-6579/aadf49.


A Universal Scaling Relation for Defining Power Spectral Bands in Mammalian Heart Rate Variability Analysis.

Behar JA, Rosenberg AA, Shemla O, Murphy KR, Koren G, Billman GE, Yaniv Y.

Front Physiol. 2018 Aug 2;9:1001. doi: 10.3389/fphys.2018.01001. eCollection 2018.


Novel Method to Efficiently Create an mHealth App: Implementation of a Real-Time Electrocardiogram R Peak Detector.

Gliner V, Behar J, Yaniv Y.

JMIR Mhealth Uhealth. 2018 May 22;6(5):e118. doi: 10.2196/mhealth.8429.


Positive Feedback Mechanisms among Local Ca Releases, NCX, and ICaL Ignite Pacemaker Action Potentials.

Lyashkov AE, Behar J, Lakatta EG, Yaniv Y, Maltsev VA.

Biophys J. 2018 Apr 24;114(8):2024. doi: 10.1016/j.bpj.2018.03.024. No abstract available.


Positive Feedback Mechanisms among Local Ca Releases, NCX, and ICaL Ignite Pacemaker Action Potentials.

Lyashkov AE, Behar J, Lakatta EG, Yaniv Y, Maltsev VA.

Biophys J. 2018 Mar 13;114(5):1176-1189. doi: 10.1016/j.bpj.2017.12.043. Erratum in: Biophys J. 2018 Apr 24;114(8):2024.


Age-related pacemaker deterioration is due to impaired intracellular and membrane mechanisms: Insights from numerical modeling.

Behar J, Yaniv Y.

J Gen Physiol. 2017 Oct 2;149(10):935-949. doi: 10.1085/jgp.201711792. Epub 2017 Sep 8.


A Method Sustaining the Bioelectric, Biophysical, and Bioenergetic Function of Cultured Rabbit Atrial Cells.

Kirschner Peretz N, Segal S, Arbel-Ganon L, Ben Jehuda R, Shemer Y, Eisen B, Davoodi M, Binah O, Yaniv Y.

Front Physiol. 2017 Aug 15;8:584. doi: 10.3389/fphys.2017.00584. eCollection 2017.


SK4 K+ channels are therapeutic targets for the treatment of cardiac arrhythmias.

Haron-Khun S, Weisbrod D, Bueno H, Yadin D, Behar J, Peretz A, Binah O, Hochhauser E, Eldar M, Yaniv Y, Arad M, Attali B.

EMBO Mol Med. 2017 Apr;9(4):415-429. doi: 10.15252/emmm.201606937.


Semi-automated program for analysis of local Ca2+ spark release with application for classification of heart cell type.

Davoodi M, Segal S, Kirschner Peretz N, Kamoun D, Yaniv Y.

Cell Calcium. 2017 Jun;64:83-90. doi: 10.1016/j.ceca.2017.02.003. Epub 2017 Feb 9.


Electrochemical Na+ and Ca2+ gradients drive coupled-clock regulation of automaticity of isolated rabbit sinoatrial nodal pacemaker cells.

Sirenko SG, Maltsev VA, Yaniv Y, Bychkov R, Yaeger D, Vinogradova T, Spurgeon HA, Lakatta EG.

Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H251-67. doi: 10.1152/ajpheart.00667.2015. Epub 2016 May 20.


Deterioration of autonomic neuronal receptor signaling and mechanisms intrinsic to heart pacemaker cells contribute to age-associated alterations in heart rate variability in vivo.

Yaniv Y, Ahmet I, Tsutsui K, Behar J, Moen JM, Okamoto Y, Guiriba TR, Liu J, Bychkov R, Lakatta EG.

Aging Cell. 2016 Aug;15(4):716-24. doi: 10.1111/acel.12483. Epub 2016 May 10.


Dynamics of PKA phosphorylation and gain of function in cardiac pacemaker cells: a computational model analysis.

Behar J, Yaniv Y.

Am J Physiol Heart Circ Physiol. 2016 May 1;310(9):H1259-66. doi: 10.1152/ajpheart.00076.2016. Epub 2016 Mar 4.


Real-time relationship between PKA biochemical signal network dynamics and increased action potential firing rate in heart pacemaker cells: Kinetics of PKA activation in heart pacemaker cells.

Yaniv Y, Ganesan A, Yang D, Ziman BD, Lyashkov AE, Levchenko A, Zhang J, Lakatta EG.

J Mol Cell Cardiol. 2015 Sep;86:168-78. doi: 10.1016/j.yjmcc.2015.07.024. Epub 2015 Aug 1.


Potential effects of intrinsic heart pacemaker cell mechanisms on dysrhythmic cardiac action potential firing.

Yaniv Y, Tsutsui K, Lakatta EG.

Front Physiol. 2015 Feb 23;6:47. doi: 10.3389/fphys.2015.00047. eCollection 2015.

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