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Items: 1 to 20 of 288

1.

Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death.

Han S, Nandy P, Austria Q, Siedlak SL, Torres S, Fujioka H, Wang W, Zhu X.

Cells. 2020 Jan 3;9(1). pii: E116. doi: 10.3390/cells9010116.

PMID:
31947766
2.

CXCL12 is involved in α-synuclein-triggered neuroinflammation of Parkinson's disease.

Li Y, Niu M, Zhao A, Kang W, Chen Z, Luo N, Zhou L, Zhu X, Lu L, Liu J.

J Neuroinflammation. 2019 Dec 12;16(1):263. doi: 10.1186/s12974-019-1646-6.

3.

Ethnicity-specific and overlapping alterations of brain hydroxymethylome in Alzheimer's disease.

Qin L, Xu Q, Li Z, Chen L, Li Y, Yang N, Liu Z, Guo J, Shen L, Allen EG, Chen C, Ma C, Wu H, Zhu X, Jin P, Tang B.

Hum Mol Genet. 2019 Dec 9. pii: ddz273. doi: 10.1093/hmg/ddz273. [Epub ahead of print]

PMID:
31814020
4.

DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1.

Liu Y, Ma X, Fujioka H, Liu J, Chen S, Zhu X.

Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25322-25328. doi: 10.1073/pnas.1906565116. Epub 2019 Nov 25.

PMID:
31767755
5.

Sequential formation of different layers of dystrophic neurites in Alzheimer's brains.

Sharoar MG, Hu X, Ma XM, Zhu X, Yan R.

Mol Psychiatry. 2019 Sep;24(9):1369-1382. doi: 10.1038/s41380-019-0396-2. Epub 2019 Mar 21.

PMID:
30899091
6.

Dynamin-like protein 1 cleavage by calpain in Alzheimer's disease.

Jiang S, Shao C, Tang F, Wang W, Zhu X.

Aging Cell. 2019 Jun;18(3):e12912. doi: 10.1111/acel.12912. Epub 2019 Feb 14.

7.

MicroRNA-26a/Death-Associated Protein Kinase 1 Signaling Induces Synucleinopathy and Dopaminergic Neuron Degeneration in Parkinson's Disease.

Su Y, Deng MF, Xiong W, Xie AJ, Guo J, Liang ZH, Hu B, Chen JG, Zhu X, Man HY, Lu Y, Liu D, Tang B, Zhu LQ.

Biol Psychiatry. 2019 May 1;85(9):769-781. doi: 10.1016/j.biopsych.2018.12.008. Epub 2018 Dec 19.

8.

Conditional Haploinsufficiency of β-Catenin Aggravates Neuronal Damage in a Paraquat-Based Mouse Model of Parkinson Disease.

Zhao F, Siedlak SL, Torres SL, Xu Q, Tang B, Zhu X.

Mol Neurobiol. 2019 Jul;56(7):5157-5166. doi: 10.1007/s12035-018-1431-z. Epub 2018 Dec 6.

PMID:
30519817
9.

The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease.

Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X.

Brain Pathol. 2019 Jul;29(4):530-543. doi: 10.1111/bpa.12691. Epub 2019 Jan 28.

PMID:
30515907
11.

Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior.

Huang X, Xiaokaiti Y, Yang J, Pan J, Li Z, Luria V, Li Y, Song G, Zhu X, Zhang HT, O'Donnell JM, Xu Y.

Neuropharmacology. 2018 Dec;143:176-185. doi: 10.1016/j.neuropharm.2018.09.039. Epub 2018 Sep 27.

PMID:
30268520
12.

Birth of JAD: 20 Years Later.

Perry G, Avila J, Tabaton M, Zhu X.

J Alzheimers Dis. 2018;62(3):901. doi: 10.3233/JAD-180120. No abstract available.

13.

Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex.

Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, Zhu X.

Mol Neurodegener. 2018 Feb 1;13(1):5. doi: 10.1186/s13024-018-0238-8.

14.

Insights into the Impact of a Membrane-Anchoring Moiety on the Biological Activities of Bivalent Compounds As Potential Neuroprotectants for Alzheimer's Disease.

He L, Jiang Y, Liu K, Gomez-Murcia V, Ma X, Torrecillas A, Chen Q, Zhu X, Lesnefsky E, Gomez-Fernandez JC, Xu B, Zhang S.

J Med Chem. 2018 Feb 8;61(3):777-790. doi: 10.1021/acs.jmedchem.7b01284. Epub 2018 Jan 5.

15.

Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model.

Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Torres S, Fujioka H, Xu Y, Perry G, Zhu X.

Hum Mol Genet. 2017 Nov 1;26(21):4118-4131. doi: 10.1093/hmg/ddx299.

16.

Endoplasmic reticulum-mitochondria tethering in neurodegenerative diseases.

Liu Y, Zhu X.

Transl Neurodegener. 2017 Aug 23;6:21. doi: 10.1186/s40035-017-0092-6. eCollection 2017. Review.

17.

Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders.

Nunomura A, Lee HG, Zhu X, Perry G.

Biochem Soc Trans. 2017 Oct 15;45(5):1053-1066. doi: 10.1042/BST20160433. Epub 2017 Aug 4. Review.

PMID:
28778984
18.

Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits.

Zhou L, Wang W, Hoppel C, Liu J, Zhu X.

Biochim Biophys Acta Mol Basis Dis. 2017 Nov;1863(11):2791-2795. doi: 10.1016/j.bbadis.2017.07.032. Epub 2017 Jul 29.

19.

NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer's Disease.

Yin J, Zhao F, Chojnacki JE, Fulp J, Klein WL, Zhang S, Zhu X.

Mol Neurobiol. 2018 Mar;55(3):1977-1987. doi: 10.1007/s12035-017-0467-9. Epub 2017 Mar 2.

20.

Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease.

Zhao F, Wang W, Wang C, Siedlak SL, Fujioka H, Tang B, Zhu X.

Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1359-1370. doi: 10.1016/j.bbadis.2017.02.016. Epub 2017 Feb 16.

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