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Items: 1 to 20 of 41


Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor.

Miao Y, Chen G, Xi X, Ma C, Wang L, Burrows JF, Duan J, Zhou M, Chen T.

Biomolecules. 2019 Jul 14;9(7). pii: E280. doi: 10.3390/biom9070280.


A Novel Kunitzin-Like Trypsin Inhibitor Isolated from Defensive Skin Secretion of Odorrana versabilis.

Dong Y, Shi D, Ying Y, Xi X, Chen X, Wang L, Zhou M, Wu Q, Ma C, Chen T.

Biomolecules. 2019 Jun 28;9(7). pii: E254. doi: 10.3390/biom9070254.


A Novel Bradykinin-Related Peptide, RVA-Thr6-BK, from the Skin Secretion of the Hejiang Frog; Ordorrana hejiangensis: Effects of Mammalian Isolated Smooth Muscle.

Wu Y, Shi D, Chen X, Wang L, Ying Y, Ma C, Xi X, Zhou M, Chen T, Shaw C.

Toxins (Basel). 2019 Jun 28;11(7). pii: E376. doi: 10.3390/toxins11070376.


Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues.

Zhou X, Shi D, Zhong R, Ye Z, Ma C, Zhou M, Xi X, Wang L, Chen T, Kwok HF.

Biomolecules. 2019 Jun 25;9(6). pii: E249. doi: 10.3390/biom9060249.


Cloning of a novel trypsin inhibitor from the Traditional Chinese medicine decoction pieces, Radix Trichosanthis.

Sang M, Ying Y, Wu Q, Ma C, Xi X, Zhou M, Wang L, Bininda-Emonds ORP, Chen T.

Anal Biochem. 2019 Aug 1;578:23-28. doi: 10.1016/j.ab.2019.02.028. Epub 2019 Mar 1.


A novel membrane-disruptive antimicrobial peptide from frog skin secretion against cystic fibrosis isolates and evaluation of anti-MRSA effect using Galleria mellonella model.

Yuan Y, Zai Y, Xi X, Ma C, Wang L, Zhou M, Shaw C, Chen T.

Biochim Biophys Acta Gen Subj. 2019 May;1863(5):849-856. doi: 10.1016/j.bbagen.2019.02.013. Epub 2019 Feb 22.


Structure-activity relationship of an antimicrobial peptide, Phylloseptin-PHa: balance of hydrophobicity and charge determines the selectivity of bioactivities.

Liu Y, Du Q, Ma C, Xi X, Wang L, Zhou M, Burrows JF, Chen T, Wang H.

Drug Des Devel Ther. 2019 Jan 23;13:447-458. doi: 10.2147/DDDT.S191072. eCollection 2019.


Modification Targeting the "Rana Box" Motif of a Novel Nigrocin Peptide From Hylarana latouchii Enhances and Broadens Its Potency Against Multiple Bacteria.

Bao K, Yuan W, Ma C, Yu X, Wang L, Hong M, Xi X, Zhou M, Chen T.

Front Microbiol. 2018 Nov 28;9:2846. doi: 10.3389/fmicb.2018.02846. eCollection 2018.


Evaluating the Bioactivity of a Novel Broad-Spectrum Antimicrobial Peptide Brevinin-1GHa from the Frog Skin Secretion of Hylarana guentheri and Its Analogues.

Chen Q, Cheng P, Ma C, Xi X, Wang L, Zhou M, Bian H, Chen T.

Toxins (Basel). 2018 Oct 13;10(10). pii: E413. doi: 10.3390/toxins10100413.


A novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells.

Chen X, Zhang L, Ma C, Zhang Y, Xi X, Wang L, Zhou M, Burrows JF, Chen T.

Biosci Rep. 2018 Nov 9;38(6). pii: BSR20180710. doi: 10.1042/BSR20180710. Print 2018 Dec 21.


Discovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells.

Zhu H, Ding X, Li W, Lu T, Ma C, Xi X, Wang L, Zhou M, Burden R, Chen T.

PeerJ. 2018 Sep 19;6:e5635. doi: 10.7717/peerj.5635. eCollection 2018.


Discovery of Novel Caeridins from the Skin Secretion of the Australian White's Tree Frog, Litoria caerulea.

Li L, Wu Q, Wang X, Lu H, Xi X, Zhou M, Watson CJ, Chen T, Wang L.

Int J Genomics. 2018 Jul 11;2018:8158453. doi: 10.1155/2018/8158453. eCollection 2018.


Biological Activities of Cationicity-Enhanced and Hydrophobicity-Optimized Analogues of an Antimicrobial Peptide, Dermaseptin-PS3, from the Skin Secretion of Phyllomedusa sauvagii.

Tan Y, Chen X, Ma C, Xi X, Wang L, Zhou M, Burrows JF, Kwok HF, Chen T.

Toxins (Basel). 2018 Aug 7;10(8). pii: E320. doi: 10.3390/toxins10080320.


Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide.

Li B, Lyu P, Xi X, Ge L, Mahadevappa R, Shaw C, Kwok HF.

J Cell Mol Med. 2018 Sep;22(9):4460-4473. doi: 10.1111/jcmm.13745. Epub 2018 Jul 11.


Evaluation of the bioactivity of a mastoparan peptide from wasp venom and of its analogues designed through targeted engineering.

Chen X, Zhang L, Wu Y, Wang L, Ma C, Xi X, Bininda-Emonds ORP, Shaw C, Chen T, Zhou M.

Int J Biol Sci. 2018 Apr 25;14(6):599-607. doi: 10.7150/ijbs.23419. eCollection 2018.


In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer.

Wei R, Wong JPC, Lyu P, Xi X, Tong O, Zhang SD, Yuen HF, Shirasawa S, Kwok HF.

J Cell Mol Med. 2018 Sep;22(9):4097-4105. doi: 10.1111/jcmm.13686. Epub 2018 May 30.


Identification of <10 KD peptides in the water extraction of Venenum Bufonis from Bufo gargarizans using Nano LC-MS/MS and De novo sequencing.

Huo Y, Xv R, Ma H, Zhou J, Xi X, Wu Q, Duan J, Zhou M, Chen T.

J Pharm Biomed Anal. 2018 Aug 5;157:156-164. doi: 10.1016/j.jpba.2018.05.027. Epub 2018 May 19.


A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea.

Zhang L, Chen X, Wu Y, Zhou M, Ma C, Xi X, Chen T, Walker B, Shaw C, Wang L.

Sci Rep. 2018 Apr 11;8(1):5851. doi: 10.1038/s41598-018-24206-4.


Discovery of Distinctin-Like-Peptide-PH (DLP-PH) From the Skin Secretion of Phyllomedusa hypochondrialis, a Prototype of a Novel Family of Antimicrobial Peptide.

Wu D, Gao Y, Tan Y, Liu Y, Wang L, Zhou M, Xi X, Ma C, Bininda-Emonds ORP, Chen T, Shaw C.

Front Microbiol. 2018 Mar 23;9:541. doi: 10.3389/fmicb.2018.00541. eCollection 2018.


Identification of novel Amurin-2 variants from the skin secretion of Rana amurensis, and the design of cationicity-enhanced analogues.

Zhang L, Chen X, Zhang Y, Ma C, Xi X, Wang L, Zhou M, Burrows JF, Chen T.

Biochem Biophys Res Commun. 2018 Mar 18;497(4):943-949. doi: 10.1016/j.bbrc.2018.01.124. Epub 2018 Jan 31.


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