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Items: 1 to 20 of 87

1.

Supramolecular Phthalocyanine Assemblies for Improved Photoacoustic Imaging and Photothermal Therapy.

Li X, Park EY, Kang Y, Kwon N, Yang M, Lee S, Kim WJ, Kim C, Yoon J.

Angew Chem Int Ed Engl. 2020 Feb 19. doi: 10.1002/anie.201916147. [Epub ahead of print]

PMID:
32077201
2.

A Supramolecular-Based Dual-Wavelength Phototherapeutic Agent with Broad-Spectrum Antimicrobial Activity Against Drug-Resistant Bacteria.

Yu ZH, Li X, Xu F, Hu XL, Yan J, Kwon N, Chen GR, Tang T, Dong X, Mai Y, Chen D, Yoon J, He XP, Tian H.

Angew Chem Int Ed Engl. 2020 Feb 24;59(9):3658-3664. doi: 10.1002/anie.201913506. Epub 2020 Jan 23.

PMID:
31868285
3.

Water-Soluble Phthalocyanines Selectively Bind to Albumin Dimers: A Green Approach Toward Enhancing Tumor-Targeted Photodynamic Therapy.

Li X, Jeong K, Lee Y, Guo T, Lee D, Park J, Kwon N, Na JH, Hong SK, Cha SS, Huang JD, Choi S, Kim S, Yoon J.

Theranostics. 2019 Aug 14;9(22):6412-6423. doi: 10.7150/thno.35210. eCollection 2019.

4.

Development of a Novel Quinoline Derivative as a P-Glycoprotein Inhibitor to Reverse Multidrug Resistance in Cancer Cells.

Zhou Y, Chung PY, Ma JY, Lam AK, Law S, Chan KW, Chan AS, Li X, Lam KH, Chui CH, Tang JC.

Biology (Basel). 2019 Oct 1;8(4). pii: E75. doi: 10.3390/biology8040075.

5.

The discovery of a potent and selective third-generation EGFR kinase inhibitor as a therapy for EGFR L858R/T790M double mutant non-small cell lung cancer.

An B, Pan T, Hu J, Pang Y, Huang L, Chan ASC, Li X, Yan J.

Eur J Med Chem. 2019 Dec 1;183:111709. doi: 10.1016/j.ejmech.2019.111709. Epub 2019 Sep 19.

PMID:
31581004
6.

Photoswitchable phthalocyanine-assembled nanoparticles for controlled "double-lock" photodynamic therapy.

Cheng HB, Li X, Kwon N, Fang Y, Baek G, Yoon J.

Chem Commun (Camb). 2019 Oct 10;55(82):12316-12319. doi: 10.1039/c9cc03960k.

PMID:
31556410
7.

Size-Tunable Targeting-Triggered Nanophotosensitizers Based on Self-Assembly of a Phthalocyanine-Biotin Conjugate for Photodynamic Therapy.

Li D, Wang XZ, Yang LF, Li SC, Hu QY, Li X, Zheng BY, Ke MR, Huang JD.

ACS Appl Mater Interfaces. 2019 Oct 9;11(40):36435-36443. doi: 10.1021/acsami.9b13861. Epub 2019 Sep 26.

PMID:
31525892
8.

Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.

Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.

Eur J Med Chem. 2019 Nov 15;182:111670. doi: 10.1016/j.ejmech.2019.111670. Epub 2019 Sep 2.

PMID:
31499359
9.

Dual functional cholinesterase and PDE4D inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of tacrine-pyrazolo[3,4-b]pyridine hybrids.

Pan T, Xie S, Zhou Y, Hu J, Luo H, Li X, Huang L.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2150-2152. doi: 10.1016/j.bmcl.2019.06.056. Epub 2019 Jun 29.

PMID:
31281020
10.

Sequential Protein-Responsive Nanophotosensitizer Complex for Enhancing Tumor-Specific Therapy.

Li X, Fan H, Guo T, Bai H, Kwon N, Kim KH, Yu S, Cho Y, Kim H, Nam KT, Yoon J, Zhang XB, Tan W.

ACS Nano. 2019 Jun 25;13(6):6702-6710. doi: 10.1021/acsnano.9b01100. Epub 2019 Jun 7.

PMID:
31184131
11.

Discovery of boron-containing compounds as Aβ aggregation inhibitors and antioxidants for the treatment of Alzheimer's disease.

Lu CJ, Hu J, Wang Z, Xie S, Pan T, Huang L, Li X.

Medchemcomm. 2018 Sep 12;9(11):1862-1870. doi: 10.1039/c8md00315g. eCollection 2018 Nov 1.

12.

In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach.

Li X, Yu S, Lee Y, Guo T, Kwon N, Lee D, Yeom SC, Cho Y, Kim G, Huang JD, Choi S, Nam KT, Yoon J.

J Am Chem Soc. 2019 Jan 23;141(3):1366-1372. doi: 10.1021/jacs.8b12167. Epub 2019 Jan 2.

PMID:
30565924
13.

Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.

Hu J, Pan T, An B, Li Z, Li X, Huang L.

Eur J Med Chem. 2019 Feb 1;163:512-526. doi: 10.1016/j.ejmech.2018.12.013. Epub 2018 Dec 7.

PMID:
30553143
14.

Supramolecular Antibacterial Materials for Combatting Antibiotic Resistance.

Li X, Bai H, Yang Y, Yoon J, Wang S, Zhang X.

Adv Mater. 2019 Feb;31(5):e1805092. doi: 10.1002/adma.201805092. Epub 2018 Dec 7. Review.

PMID:
30536445
15.

Design, synthesis, and biological evaluation of histone deacetylase inhibitors possessing glutathione peroxidase-like and antioxidant activities against Alzheimer's disease.

Hu J, An B, Pan T, Li Z, Huang L, Li X.

Bioorg Med Chem. 2018 Nov 15;26(21):5718-5729. doi: 10.1016/j.bmc.2018.10.022. Epub 2018 Oct 24.

PMID:
30385227
16.

Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma.

Chung PY, Lam PL, Zhou YY, Gasparello J, Finotti A, Chilin A, Marzaro G, Gambari R, Bian ZX, Kwok WM, Wong WY, Wang X, Lam AK, Chan AS, Li X, Ma JY, Chui CH, Lam KH, Tang JC.

Cells. 2018 Oct 22;7(10). pii: E177. doi: 10.3390/cells7100177.

17.

Mesenchymal stem cell-driven activatable photosensitizers for precision photodynamic oncotherapy.

Li X, Kim CY, Shin JM, Lee D, Kim G, Chung HM, Hong KS, Yoon J.

Biomaterials. 2018 Dec;187:18-26. doi: 10.1016/j.biomaterials.2018.09.041. Epub 2018 Sep 28.

PMID:
30290226
18.

Design, Synthesis, and Biological Evaluation of Dual-Target Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 9A (PDE9A) for the Treatment of Alzheimer's Disease.

Hu J, Huang YD, Pan T, Zhang T, Su T, Li X, Luo HB, Huang L.

ACS Chem Neurosci. 2019 Jan 16;10(1):537-551. doi: 10.1021/acschemneuro.8b00376. Epub 2018 Oct 12.

PMID:
30252439
19.

Expression of Insulin-Like Growth Factor Binding Protein-5 (IGFBP5) Reverses Cisplatin-Resistance in Esophageal Carcinoma.

Chan D, Zhou Y, Chui CH, Lam KH, Law S, Chan AS, Li X, Lam AK, Tang JCO.

Cells. 2018 Sep 20;7(10). pii: E143. doi: 10.3390/cells7100143.

20.

Evaluation of 4-phenylamino-substituted naphthalene-1,2-diones as tubulin polymerization inhibitors.

Yang H, An B, Li X, Zeng W.

Bioorg Med Chem Lett. 2018 Oct 1;28(18):3057-3063. doi: 10.1016/j.bmcl.2018.07.047. Epub 2018 Aug 1.

PMID:
30093295

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