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Items: 1 to 20 of 26


ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in CLL mouse model.

Chiang CL, Goswami S, Frissora FW, Xie Z, Yan PS, Bundschuh R, Walker LA, Huang X, Mani R, Mo XM, Baskar S, Rader C, Phelps MA, Marcucci G, Byrd JC, Lee LJ, Muthusamy N.

Blood. 2019 May 31. pii: blood.2018882290. doi: 10.1182/blood.2018882290. [Epub ahead of print]


Migration and distribution of cadmium in aquatic environment: The important role of natural biofilms.

Hua X, Huang X, Tian J, Dong D, Liang D, Guo Z.

Sci Total Environ. 2019 Jun 20;670:478-485. doi: 10.1016/j.scitotenv.2019.03.246. Epub 2019 Mar 18.


Managing nitrogen to restore water quality in China.

Yu C, Huang X, Chen H, Godfray HCJ, Wright JS, Hall JW, Gong P, Ni S, Qiao S, Huang G, Xiao Y, Zhang J, Feng Z, Ju X, Ciais P, Stenseth NC, Hessen DO, Sun Z, Yu L, Cai W, Fu H, Huang X, Zhang C, Liu H, Taylor J.

Nature. 2019 Mar;567(7749):516-520. doi: 10.1038/s41586-019-1001-1. Epub 2019 Feb 28.


Ongoing clonal evolution in chronic myelomonocytic leukemia on hypomethylating agents: a computational perspective.

Than H, Qiao Y, Huang X, Yan D, Khorashad JS, Pomicter AD, Kovacsovics TJ, Marth GT, O'Hare T, Deininger MW.

Leukemia. 2018 Sep;32(9):2049-2054. doi: 10.1038/s41375-018-0050-z. Epub 2018 Mar 27. No abstract available.


Solving global shallow water equations on heterogeneous supercomputers.

Fu H, Gan L, Yang C, Xue W, Wang L, Wang X, Huang X, Yang G.

PLoS One. 2017 Mar 10;12(3):e0172583. doi: 10.1371/journal.pone.0172583. eCollection 2017.


C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells.

Gardiner JD, Abegglen LM, Huang X, Carter BE, Schackmann EA, Stucki M, Paxton CN, Lor Randall R, Amatruda JF, Putnam AR, Kovar H, Lessnick SL, Schiffman JD.

Oncotarget. 2017 Apr 18;8(16):26013-26026. doi: 10.18632/oncotarget.14847.


Controllable Large-Scale Transfection of Primary Mammalian Cardiomyocytes on a Nanochannel Array Platform.

Chang L, Gallego-Perez D, Chiang CL, Bertani P, Kuang T, Sheng Y, Chen F, Chen Z, Shi J, Yang H, Huang X, Malkoc V, Lu W, Lee LJ.

Small. 2016 Nov;12(43):5971-5980. doi: 10.1002/smll.201601465. Epub 2016 Sep 20.


Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia.

Huang X, Schwind S, Santhanam R, Eisfeld AK, Chiang CL, Lankenau M, Yu B, Hoellerbauer P, Jin Y, Tarighat SS, Khalife J, Walker A, Perrotti D, Bloomfield CD, Wang H, Lee RJ, Lee LJ, Marcucci G.

Oncotarget. 2016 Sep 13;7(37):59273-59286. doi: 10.18632/oncotarget.11150.


Preparation of Targeted Anionic Lipid-Coated Polyplexes for MicroRNA Delivery.

Huang X, Zhang M, Wang X, Lee LJ, Lee RJ.

Methods Mol Biol. 2016;1445:201-13. doi: 10.1007/978-1-4939-3718-9_13.


Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia.

Maharry SE, Walker CJ, Liyanarachchi S, Mehta S, Patel M, Bainazar MA, Huang X, Lankenau MA, Hoag KW, Ranganathan P, Garzon R, Blachly JS, Guttridge DC, Bloomfield CD, de la Chapelle A, Eisfeld AK.

Cancer Discov. 2016 Sep;6(9):1036-51. doi: 10.1158/2159-8290.CD-16-0023. Epub 2016 Jun 27.


Induced Apoptosis Investigation in Wild-type and FLT3-ITD Acute Myeloid Leukemia Cells by Nanochannel Electroporation and Single-cell qRT-PCR.

Gao K, Huang X, Chiang CL, Wang X, Chang L, Boukany P, Marcucci G, Lee R, Lee LJ.

Mol Ther. 2016 May;24(5):956-64. doi: 10.1038/mt.2016.6. Epub 2016 Jan 19.


Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia.

Zhao X, Huang X, Wang X, Wu Y, Eisfeld AK, Schwind S, Gallego-Perez D, Boukany PE, Marcucci GI, Lee LJ.

Adv Sci (Weinh). 2015 Jul 16;2(12):1500111. eCollection 2015 Dec.


Targeted delivery of tumor suppressor microRNA-1 by transferrin-conjugated lipopolyplex nanoparticles to patient-derived glioblastoma stem cells.

Wang X, Huang X, Yang Z, Gallego-Perez D, Ma J, Zhao X, Xie J, Nakano I, Lee LJ.

Curr Pharm Biotechnol. 2014;15(9):839-46.


A microfluidic method to synthesize transferrin-lipid nanoparticles loaded with siRNA LOR-1284 for therapy of acute myeloid leukemia.

Yang Z, Yu B, Zhu J, Huang X, Xie J, Xu S, Yang X, Wang X, Yung BC, Lee LJ, Lee RJ, Teng L.

Nanoscale. 2014 Aug 21;6(16):9742-51. doi: 10.1039/c4nr01510j. Epub 2014 Jul 8.


Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway.

Eisfeld AK, Schwind S, Patel R, Huang X, Santhanam R, Walker CJ, Markowitz J, Hoag KW, Jarvinen TM, Leffel B, Perrotti D, Carson WE 3rd, Marcucci G, Bloomfield CD, de la Chapelle A.

Sci Signal. 2014 Apr 15;7(321):ra36. doi: 10.1126/scisignal.2004762.


Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML.

Havelange V, Ranganathan P, Geyer S, Nicolet D, Huang X, Yu X, Volinia S, Kornblau SM, Andreeff M, Croce CM, Marcucci G, Bloomfield CD, Garzon R.

Blood. 2014 Apr 10;123(15):2412-5. doi: 10.1182/blood-2013-10-532374. Epub 2014 Mar 4.


SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome.

Alachkar H, Santhanam R, Maharry K, Metzeler KH, Huang X, Kohlschmidt J, Mendler JH, Benito JM, Hickey C, Neviani P, Dorrance AM, Anghelina M, Khalife J, Tarighat SS, Volinia S, Whitman SP, Paschka P, Hoellerbauer P, Wu YZ, Han L, Bolon BN, Blum W, Mrózek K, Carroll AJ, Perrotti D, Andreeff M, Caligiuri MA, Konopleva M, Garzon R, Bloomfield CD, Marcucci G.

J Clin Invest. 2014 Apr;124(4):1512-24. doi: 10.1172/JCI70921. Epub 2014 Mar 3.


NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation.

Eisfeld AK, Schwind S, Hoag KW, Walker CJ, Liyanarachchi S, Patel R, Huang X, Markowitz J, Duan W, Otterson GA, Carson WE 3rd, Marcucci G, Bloomfield CD, de la Chapelle A.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4179-84. doi: 10.1073/pnas.1401727111. Epub 2014 Feb 28.


Detection of extracellular RNAs in cancer and viral infection via tethered cationic lipoplex nanoparticles containing molecular beacons.

Wu Y, Kwak KJ, Agarwal K, Marras A, Wang C, Mao Y, Huang X, Ma J, Yu B, Lee R, Vachani A, Marcucci G, Byrd JC, Muthusamy N, Otterson G, Huang K, Castro CE, Paulaitis M, Nana-Sinkam SP, Lee LJ.

Anal Chem. 2013 Dec 3;85(23):11265-74. doi: 10.1021/ac401983w. Epub 2013 Nov 13.


Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia.

Huang X, Schwind S, Yu B, Santhanam R, Wang H, Hoellerbauer P, Mims A, Klisovic R, Walker AR, Chan KK, Blum W, Perrotti D, Byrd JC, Bloomfield CD, Caligiuri MA, Lee RJ, Garzon R, Muthusamy N, Lee LJ, Marcucci G.

Clin Cancer Res. 2013 May 1;19(9):2355-67. doi: 10.1158/1078-0432.CCR-12-3191. Epub 2013 Mar 14.

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