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Items: 1 to 20 of 141


Treatment of human T-cell acute lymphoblastic leukemia cells with CFTR inhibitor CFTRinh-172.

Liu M, Liao H, Chen Y, Lin Z, Liu Y, Zhang X, Chan HC, Sun H.

Leuk Res. 2019 Sep 13;86:106225. doi: 10.1016/j.leukres.2019.106225. [Epub ahead of print]


Overcoming adaptive therapy resistance in AML by targeting immune response pathways.

Melgar K, Walker MM, Jones LM, Bolanos LC, Hueneman K, Wunderlich M, Jiang JK, Wilson KM, Zhang X, Sutter P, Wang A, Xu X, Choi K, Tawa G, Lorimer D, Abendroth J, O'Brien E, Hoyt SB, Berman E, Famulare CA, Mulloy JC, Levine RL, Perentesis JP, Thomas CJ, Starczynowski DT.

Sci Transl Med. 2019 Sep 4;11(508). pii: eaaw8828. doi: 10.1126/scitranslmed.aaw8828.


High-throughput screening identifies candidate drugs for the treatment of recurrent respiratory papillomatosis.

Alkhilaiwi F, Paul S, Zhou D, Zhang X, Wang F, Palechor-Ceron N, Wilson K, Guha R, Ferrer M, Grant N, Thomas C, Schlegel R, Yuan H.

Papillomavirus Res. 2019 Aug 22;8:100181. doi: 10.1016/j.pvr.2019.100181. [Epub ahead of print]


Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis.

Hou J, Ju J, Zhang Z, Zhao C, Li Z, Zheng J, Sheng T, Zhang H, Hu L, Yu X, Zhang W, Li Y, Wu M, Ma H, Zhang X, He S.

Cell Death Dis. 2019 Jun 24;10(7):493. doi: 10.1038/s41419-019-1735-6.


Aircraft Pose Estimation Based on Geometry Structure Features and Line Correspondences.

Teng X, Yu Q, Luo J, Wang G, Zhang X.

Sensors (Basel). 2019 May 9;19(9). pii: E2165. doi: 10.3390/s19092165.


Structural optimization on a virtual screening hit of smoothened receptor.

Song S, Jiang J, Zhao L, Wang Q, Lu W, Zheng C, Zhang J, Ma H, Tian S, Zheng J, Luo L, Li Y, Yang ZJ, Zhang X.

Eur J Med Chem. 2019 Jun 15;172:1-15. doi: 10.1016/j.ejmech.2019.03.057. Epub 2019 Mar 26.


Foxg1 Directly Represses Dbx1 to Confine the POA and Subsequently Regulate Ventral Telencephalic Patterning.

Du A, Wu X, Chen H, Bai QR, Han X, Liu B, Zhang X, Ding Z, Shen Q, Zhao C.

Cereb Cortex. 2019 Mar 4. pii: bhz037. doi: 10.1093/cercor/bhz037. [Epub ahead of print]


Pose Estimation for Straight Wing Aircraft Based on Consistent Line Clustering and Planes Intersection.

Teng X, Yu Q, Luo J, Zhang X, Wang G.

Sensors (Basel). 2019 Jan 16;19(2). pii: E342. doi: 10.3390/s19020342.


Enhanced Light-Driven Hydrogen-Production Activity Induced by Accelerated Interfacial Charge Transfer in Donor-Acceptor Conjugated Polymers/TiO2 Hybrid.

Chen B, Wang X, Dong W, Zhang X, Rao L, Chen H, Huang D, Xiang Y.

Chemistry. 2019 Mar 1;25(13):3362-3368. doi: 10.1002/chem.201805740. Epub 2019 Feb 6.


Defective CFTR promotes intestinal proliferation via inhibition of the hedgehog pathway during cystic fibrosis.

Liu K, Wang X, Zou C, Zhang J, Chen H, Tsang L, Yu MK, Chung YW, Wang J, Dai Y, Liu Y, Zhang X.

Cancer Lett. 2019 Apr 1;446:15-24. doi: 10.1016/j.canlet.2018.12.018. Epub 2019 Jan 11.


Hydrophilicity-Controlled Conjugated Microporous Polymers for Enhanced Visible-Light-Driven Photocatalytic H2 Evolution.

Wang X, Chen B, Dong W, Zhang X, Li Z, Xiang Y, Chen H.

Macromol Rapid Commun. 2019 Mar;40(6):e1800494. doi: 10.1002/marc.201800494. Epub 2018 Dec 17.


Reference image based phase unwrapping framework for a structured light system.

Bao W, Xiao X, Xu Y, Zhang X.

Opt Express. 2018 Oct 29;26(22):29588-29599. doi: 10.1364/OE.26.029588.


High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer.

Jansson KH, Tucker JB, Stahl LE, Simmons JK, Fuller C, Beshiri ML, Agarwal S, Fang L, Hynes PG, Alilin AN, Lake R, Abbey YC, Cawley J, Tice CM, Yin J, McKnight C, Klummp-Thomas C, Zhang X, Guha R, Hoover S, Simpson RM, Nguyen HM, Corey E, Thomas CJ, Proia DA, Kelly K.

Sci Rep. 2018 Nov 22;8(1):17239. doi: 10.1038/s41598-018-35417-0.


A Volume Measurement Method for Lunar Soil Collection Based on a Single Monitoring Camera.

Ding S, Zhang X, Yu Q, Li L, Wang J.

Sensors (Basel). 2018 Oct 10;18(10). pii: E3394. doi: 10.3390/s18103394.


Development of Adenosine A2A Receptor Antagonists for the Treatment of Parkinson's Disease: A Recent Update and Challenge.

Zheng J, Zhang X, Zhen X.

ACS Chem Neurosci. 2019 Feb 20;10(2):783-791. doi: 10.1021/acschemneuro.8b00313. Epub 2018 Sep 21.


A novel hedgehog inhibitor for the treatment of hematological malignancies.

Lin P, He Y, Chen G, Ma H, Zheng J, Zhang Z, Cao B, Zhang H, Zhang X, Mao X.

Anticancer Drugs. 2018 Nov;29(10):995-1003. doi: 10.1097/CAD.0000000000000679.


Preconditioning Enhances the Therapeutic Effects of Mesenchymal Stem Cells on Colitis Through PGE2-Mediated T-Cell Modulation.

Yang FY, Chen R, Zhang X, Huang B, Tsang LL, Li X, Jiang X.

Cell Transplant. 2018 Sep;27(9):1352-1367. doi: 10.1177/0963689718780304. Epub 2018 Aug 10.


Discovery of a potent hedgehog pathway inhibitor capable of activating caspase8-dependent apoptosis.

Chen Q, Zhang H, Wu M, Wang Q, Luo L, Ma H, Zhang X, He S.

J Pharmacol Sci. 2018 Jul;137(3):256-264. doi: 10.1016/j.jphs.2018.07.001. Epub 2018 Jul 10.


MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.

Yohe ME, Gryder BE, Shern JF, Song YK, Chou HC, Sindiri S, Mendoza A, Patidar R, Zhang X, Guha R, Butcher D, Isanogle KA, Robinson CM, Luo X, Chen JQ, Walton A, Awasthi P, Edmondson EF, Difilippantonio S, Wei JS, Zhao K, Ferrer M, Thomas CJ, Khan J.

Sci Transl Med. 2018 Jul 4;10(448). pii: eaan4470. doi: 10.1126/scitranslmed.aan4470.


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