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Items: 1 to 20 of 67

1.

Hot melt extrusion technology for improved dissolution, solubility and "spring-parachute" processes of amorphous self-micellizing solid dispersions containing BCS II drugs indomethacin and fenofibrate: Profiles and mechanisms.

Shi NQ, Wang SR, Zhang Y, Huo JS, Wang LN, Cai JH, Li ZQ, Xiang B, Qi XR.

Eur J Pharm Sci. 2019 Mar 15;130:78-90. doi: 10.1016/j.ejps.2019.01.019. Epub 2019 Jan 23.

PMID:
30684657
2.

The Influence of Cellulosic Polymer's Variables on Dissolution/Solubility of Amorphous Felodipine and Crystallization Inhibition from a Supersaturated State.

Shi NQ, Jin Y, Zhang Y, Che XX, Xiao X, Cui GH, Chen YZ, Feng B, Li ZQ, Qi XR.

AAPS PharmSciTech. 2018 Dec 17;20(1):12. doi: 10.1208/s12249-018-1266-y.

PMID:
30560388
3.

Enhancing solid tumor therapy with sequential delivery of dexamethasone and docetaxel engineered in a single carrier to overcome stromal resistance to drug delivery.

Zhang L, Su H, Liu Y, Pang N, Li J, Qi XR.

J Control Release. 2019 Jan 28;294:1-16. doi: 10.1016/j.jconrel.2018.12.004. Epub 2018 Dec 5.

PMID:
30527754
4.

Prior anti-CAFs break down the CAFs barrier and improve accumulation of docetaxel micelles in tumor.

Pang N, Li J, Sun A, Yang Z, Cheng S, Qi XR.

Int J Nanomedicine. 2018 Oct 4;13:5971-5990. doi: 10.2147/IJN.S171224. eCollection 2018.

5.

Deepened cellular/subcellular interface penetration and enhanced antitumor efficacy of cyclic peptidic ligand-decorated accelerating active targeted nanomedicines.

Shi NQ, Li Y, Zhang Y, Li ZQ, Qi XR.

Int J Nanomedicine. 2018 Sep 19;13:5537-5559. doi: 10.2147/IJN.S172556. eCollection 2018.

6.

Construction of Hyaluronic Tetrasaccharide Clusters Modified Polyamidoamine siRNA Delivery System.

Ma Y, Sha M, Cheng S, Yao W, Li Z, Qi XR.

Nanomaterials (Basel). 2018 Jun 14;8(6). pii: E433. doi: 10.3390/nano8060433.

7.

Intelligent "Peptide-Gathering Mechanical Arm" Tames Wild "Trojan-Horse" Peptides for the Controlled Delivery of Cancer Nanotherapeutics.

Shi NQ, Li Y, Zhang Y, Shen N, Qi L, Wang SR, Qi XR.

ACS Appl Mater Interfaces. 2017 Dec 6;9(48):41767-41781. doi: 10.1021/acsami.7b15523. Epub 2017 Nov 21.

PMID:
29161013
8.

Self-micellizing solid dispersions enhance the properties and therapeutic potential of fenofibrate: Advantages, profiles and mechanisms.

Shi NQ, Zhang Y, Li Y, Lai HW, Xiao X, Feng B, Qi XR.

Int J Pharm. 2017 Aug 7;528(1-2):563-577. doi: 10.1016/j.ijpharm.2017.06.017. Epub 2017 Jun 7.

PMID:
28602799
9.

Treating metastatic triple negative breast cancer with CD44/neuropilin dual molecular targets of multifunctional nanoparticles.

Liang DS, Zhang WJ, Wang AT, Su HT, Zhong HJ, Qi XR.

Biomaterials. 2017 Aug;137:23-36. doi: 10.1016/j.biomaterials.2017.05.022. Epub 2017 May 13.

PMID:
28528300
10.

Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation.

Liu YJ, Ma YC, Zhang WJ, Yang ZZ, Liang DS, Wu ZF, Qi XR.

Oncotarget. 2017 Jun 27;8(26):42495-42509. doi: 10.18632/oncotarget.17205.

11.

Enhancing siRNA-based cancer therapy using a new pH-responsive activatable cell-penetrating peptide-modified liposomal system.

Xiang B, Jia XL, Qi JL, Yang LP, Sun WH, Yan X, Yang SK, Cao DY, Du Q, Qi XR.

Int J Nanomedicine. 2017 Mar 28;12:2385-2405. doi: 10.2147/IJN.S129574. eCollection 2017.

12.

Taming the Wildness of "Trojan-Horse" Peptides by Charge-Guided Masking and Protease-Triggered Demasking for the Controlled Delivery of Antitumor Agents.

Shi NQ, Qi XR.

ACS Appl Mater Interfaces. 2017 Mar 29;9(12):10519-10529. doi: 10.1021/acsami.7b01056. Epub 2017 Mar 14.

PMID:
28290666
13.

Delivering siRNA and Chemotherapeutic Molecules Across BBB and BTB for Intracranial Glioblastoma Therapy.

Yang ZZ, Gao W, Liu YJ, Pang N, Qi XR.

Mol Pharm. 2017 Apr 3;14(4):1012-1022. doi: 10.1021/acs.molpharmaceut.6b00819. Epub 2017 Mar 2.

PMID:
28252970
14.

On the inherent properties of Soluplus and its application in ibuprofen solid dispersions generated by microwave-quench cooling technology.

Shi NQ, Lai HW, Zhang Y, Feng B, Xiao X, Zhang HM, Li ZQ, Qi XR.

Pharm Dev Technol. 2018 Jul;23(6):573-586. doi: 10.1080/10837450.2016.1256409. Epub 2016 Nov 16.

PMID:
27824281
15.

Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity.

Su HT, Li X, Liang DS, Qi XR.

Oncotarget. 2016 Aug 9;7(32):51535-51552. doi: 10.18632/oncotarget.10493.

16.

[Activatable cell-penetrating peptides: a potential activatable modality for diseases diagnosis and therapy].

Yang SK, Yan X, Sun WH, Du Q, Xiang B, Cao DY, Qi XR.

Yao Xue Xue Bao. 2016 Apr;51(4):529-35. Review. Chinese.

PMID:
29859520
17.

[Rules and characteristics of crystallization inhibition of cellulose polymers against drugs in supersaturated states].

Shi NQ, Zhang Y, Zhang XR, Feng B, Li ZQ, Qi XR.

Yao Xue Xue Bao. 2016 Mar;51(3):462-8. Chinese.

PMID:
29859030
18.

Tumor-specific penetrating peptides-functionalized hyaluronic acid-d-α-tocopheryl succinate based nanoparticles for multi-task delivery to invasive cancers.

Liang DS, Su HT, Liu YJ, Wang AT, Qi XR.

Biomaterials. 2015 Dec;71:11-23. doi: 10.1016/j.biomaterials.2015.08.035. Epub 2015 Aug 20.

PMID:
26310359
19.

[The application of enzyme-sensitive activatable cell-penetrating peptides to targeted delivery system].

He F, Cao L, Zhang XJ, Xiang B, Cao DY, Qi XR.

Yao Xue Xue Bao. 2015 Feb;50(2):141-7. Review. Chinese.

PMID:
25975019
20.

Enhance Cancer Cell Recognition and Overcome Drug Resistance Using Hyaluronic Acid and α-Tocopheryl Succinate Based Multifunctional Nanoparticles.

Liang D, Wang AT, Yang ZZ, Liu YJ, Qi XR.

Mol Pharm. 2015 Jun 1;12(6):2189-202. doi: 10.1021/acs.molpharmaceut.5b00129. Epub 2015 May 18.

PMID:
25945733

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