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Items: 1 to 20 of 29

1.

Web Application for Quantification of Traumatic Brain Injury-Induced Cortical Lesions in Adult Mice.

Ciszek R, Andrade P, Tapiala J, Pitkänen A, Ndode-Ekane XE.

Neuroinformatics. 2019 Dec 4. doi: 10.1007/s12021-019-09444-9. [Epub ahead of print]

PMID:
31802356
2.

In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury-Lessons Learned.

Lipponen A, Natunen T, Hujo M, Ciszek R, Hämäläinen E, Tohka J, Hiltunen M, Paananen J, Poulsen D, Kansanen E, Ekolle Ndode-Ekane X, Levonen AL, Pitkänen A.

Int J Mol Sci. 2019 Oct 29;20(21). pii: E5395. doi: 10.3390/ijms20215395.

3.

Acute Downregulation of Novel Hypothalamic Protein Sushi Repeat-Containing Protein X-Linked 2 after Experimental Traumatic Brain Injury.

Anwer M, Lara-Valderrabano L, Karttunen J, Ndode-Ekane XE, Puhakka N, Pitkänen A.

J Neurotrauma. 2019 Dec 5. doi: 10.1089/neu.2019.6739. [Epub ahead of print]

PMID:
31650880
4.

Lateral fluid-percussion injury leads to pituitary atrophy in rats.

Anwer M, Immonen R, Hayward NMEA, Ndode-Ekane XE, Puhakka N, Gröhn O, Pitkänen A.

Sci Rep. 2019 Aug 14;9(1):11819. doi: 10.1038/s41598-019-48404-w.

5.

Genotype and Injury Effect on the Expression of a Novel Hypothalamic Protein Sushi Repeat-Containing Protein X-Linked 2 (SRPX2).

Anwer M, Bolkvadze T, Puhakka N, Ndode-Ekane XE, Pitkänen A.

Neuroscience. 2019 Sep 1;415:184-200. doi: 10.1016/j.neuroscience.2019.07.040. Epub 2019 Jul 27.

PMID:
31362033
6.

Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis.

Casillas-Espinosa PM, Andrade P, Santana-Gomez C, Paananen T, Smith G, Ali I, Ciszek R, Ndode-Ekane XE, Brady RD, Tohka J, Hudson MR, Perucca P, Braine EL, Immonen R, Puhakka N, Shultz SR, Jones NC, Staba RJ, Pitkänen A, O'Brien TJ.

Epilepsy Res. 2019 Oct;156:106131. doi: 10.1016/j.eplepsyres.2019.04.011. Epub 2019 Apr 27.

PMID:
31076256
7.

Harmonization of pipeline for detection of HFOs in a rat model of post-traumatic epilepsy in preclinical multicenter study on post-traumatic epileptogenesis.

Santana-Gomez C, Andrade P, Hudson MR, Paananen T, Ciszek R, Smith G, Ali I, Rundle BK, Ndode-Ekane XE, Casillas-Espinosa PM, Immonen R, Puhakka N, Jones N, Brady RD, Perucca P, Shultz SR, Pitkänen A, O'Brien TJ, Staba R.

Epilepsy Res. 2019 Oct;156:106110. doi: 10.1016/j.eplepsyres.2019.03.008. Epub 2019 Mar 15.

PMID:
30981541
8.

Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility.

Kyyriäinen J, Bolkvadze T, Koivisto H, Lipponen A, Pérez LO, Ekolle Ndode-Ekane X, Tanila H, Pitkänen A.

Epilepsy Res. 2019 Mar;151:67-74. doi: 10.1016/j.eplepsyres.2019.02.009. Epub 2019 Feb 25.

PMID:
30836238
9.

Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis.

Ndode-Ekane XE, Santana-Gomez C, Casillas-Espinosa PM, Ali I, Brady RD, Smith G, Andrade P, Immonen R, Puhakka N, Hudson MR, Braine EL, Shultz SR, Staba RJ, O'Brien TJ, Pitkänen A.

Epilepsy Res. 2019 Mar;151:7-16. doi: 10.1016/j.eplepsyres.2019.01.006. Epub 2019 Jan 18.

PMID:
30711714
10.

Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis.

Immonen R, Smith G, Brady RD, Wright D, Johnston L, Harris NG, Manninen E, Salo R, Branch C, Duncan D, Cabeen R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Shultz SR, Andrade P, Puhakka N, Staba RJ, O'Brien TJ, Toga AW, Pitkänen A, Gröhn O.

Epilepsy Res. 2019 Feb;150:46-57. doi: 10.1016/j.eplepsyres.2019.01.001. Epub 2019 Jan 7.

PMID:
30641351
11.

Informatics tools to assess the success of procedural harmonization in preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis.

Ciszek R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Smith G, Puhakka N, Lapinlampi N, Andrade P, Kamnaksh A, Immonen R, Paananen T, Hudson MR, Brady RD, Shultz SR, O'Brien TJ, Staba RJ, Tohka J, Pitkänen A.

Epilepsy Res. 2019 Feb;150:17-26. doi: 10.1016/j.eplepsyres.2018.12.010. Epub 2018 Dec 27.

PMID:
30605864
12.

Harmonization of pipeline for preclinical multicenter plasma protein and miRNA biomarker discovery in a rat model of post-traumatic epileptogenesis.

Kamnaksh A, Puhakka N, Ali I, Smith G, Aniceto R, McCullough J, Das Gupta S, Ndode-Ekane XE, Brady R, Casillas-Espinosa P, Hudson M, Santana-Gomez C, Immonen R, Abreu PA, Jones N, Shultz S, Staba RJ, O'Brien TJ, Agoston D, Pitkänen A.

Epilepsy Res. 2019 Jan;149:92-101. doi: 10.1016/j.eplepsyres.2018.11.009. Epub 2018 Nov 26.

PMID:
30553097
13.

Acute Non-Convulsive Status Epilepticus after Experimental Traumatic Brain Injury in Rats.

Andrade P, Banuelos-Cabrera I, Lapinlampi N, Paananen T, Ciszek R, Ndode-Ekane XE, Pitkänen A.

J Neurotrauma. 2019 Jun;36(11):1890-1907. doi: 10.1089/neu.2018.6107. Epub 2019 Feb 25.

PMID:
30543155
14.

A web-based application for generating 2D-unfolded cortical maps to analyze the location and extent of cortical lesions following traumatic brain injury in adult rats.

Andrade P, Ciszek R, Pitkänen A, Ndode-Ekane XE.

J Neurosci Methods. 2018 Oct 1;308:330-336. doi: 10.1016/j.jneumeth.2018.08.028. Epub 2018 Sep 5.

PMID:
30194043
15.

Detection of Hyperexcitability by Functional Magnetic Resonance Imaging after Experimental Traumatic Brain Injury.

Huttunen JK, Airaksinen AM, Barba C, Colicchio G, Niskanen JP, Shatillo A, Sierra Lopez A, Ndode-Ekane XE, Pitkänen A, Gröhn OH.

J Neurotrauma. 2018 Nov 15;35(22):2708-2717. doi: 10.1089/neu.2017.5308. Epub 2018 Sep 27.

PMID:
30019618
16.

T-cell infiltration into the perilesional cortex is long-lasting and associates with poor somatomotor recovery after experimental traumatic brain injury.

Ndode-Ekane XE, Matthiesen L, Bañuelos-Cabrera I, Palminha CAP, Pitkänen A.

Restor Neurol Neurosci. 2018;36(4):485-501. doi: 10.3233/RNN-170811.

PMID:
29889085
17.

Epilepsy biomarkers - Toward etiology and pathology specificity.

Pitkänen A, Ekolle Ndode-Ekane X, Lapinlampi N, Puhakka N.

Neurobiol Dis. 2019 Mar;123:42-58. doi: 10.1016/j.nbd.2018.05.007. Epub 2018 May 18. Review.

PMID:
29782966
18.

Sushi repeat-containing protein X-linked 2: A novel phylogenetically conserved hypothalamo-pituitary protein.

Anwer M, Bolkvadze T, Ndode-Ekane XE, Puhakka N, Rauramaa T, Leinonen V, van Vliet EA, Swaab DF, Haapasalo A, Leskelä S, Bister N, Malm T, Carlson S, Aronica E, Pitkänen A.

J Comp Neurol. 2018 Aug 1;526(11):1806-1819. doi: 10.1002/cne.24449. Epub 2018 May 1.

PMID:
29663392
19.

Disease-modifying effect of atipamezole in a model of post-traumatic epilepsy.

Nissinen J, Andrade P, Natunen T, Hiltunen M, Malm T, Kanninen K, Soares JI, Shatillo O, Sallinen J, Ndode-Ekane XE, Pitkänen A.

Epilepsy Res. 2017 Oct;136:18-34. doi: 10.1016/j.eplepsyres.2017.07.005. Epub 2017 Jul 12.

PMID:
28753497
20.

Dynamics of PDGFRβ expression in different cell types after brain injury.

Kyyriäinen J, Ekolle Ndode-Ekane X, Pitkänen A.

Glia. 2017 Feb;65(2):322-341. doi: 10.1002/glia.23094. Epub 2016 Oct 25.

PMID:
27778377

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