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Items: 1 to 20 of 37


A nematode sterol C4α-methyltransferase catalyzes a new methylation reaction responsible for sterol diversity.

Zhou W, Fisher PM, Vanderloop BH, Shen Y, Shi H, Maldonado AJ, Leaver DJ, Nes WD.

J Lipid Res. 2019 Sep 23. pii: jlr.RA119000317. doi: 10.1194/jlr.RA119000317. [Epub ahead of print]


Transcriptomic and proteomic responses to very low CO2 suggest multiple carbon concentrating mechanisms in Nannochloropsis oceanica.

Wei L, El Hajjami M, Shen C, You W, Lu Y, Li J, Jing X, Hu Q, Zhou W, Poetsch A, Xu J.

Biotechnol Biofuels. 2019 Jun 28;12:168. doi: 10.1186/s13068-019-1506-8. eCollection 2019.


Steroidal antibiotics are antimetabolites of Acanthamoeba steroidogenesis with phylogenetic implications.

Zhou W, Ramos E, Zhu X, Fisher PM, Kidane ME, Vanderloop BH, Thomas CD, Yan J, Singha U, Chaudhuri M, Nagel MT, Nes WD.

J Lipid Res. 2019 May;60(5):981-994. doi: 10.1194/jlr.M091587. Epub 2019 Feb 1.


Phytosterol Composition of Arachis hypogaea Seeds from Different Maturity Classes.

Zhou W, Branch WD, Gilliam L, Marshall JA.

Molecules. 2018 Dec 29;24(1). pii: E106. doi: 10.3390/molecules24010106.


Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri.

Zhou W, Debnath A, Jennings G, Hahn HJ, Vanderloop BH, Chaudhuri M, Nes WD, Podust LM.

PLoS Pathog. 2018 Sep 13;14(9):e1007245. doi: 10.1371/journal.ppat.1007245. eCollection 2018 Sep.


Functional importance for developmental regulation of sterol biosynthesis in Acanthamoeba castellanii.

Zhou W, Warrilow AGS, Thomas CD, Ramos E, Parker JE, Price CL, Vanderloop BH, Fisher PM, Loftis MD, Kelly DE, Kelly SL, Nes WD.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1164-1178. doi: 10.1016/j.bbalip.2018.07.004. Epub 2018 Jul 22.


CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).

Debnath A, Calvet CM, Jennings G, Zhou W, Aksenov A, Luth MR, Abagyan R, Nes WD, McKerrow JH, Podust LM.

PLoS Negl Trop Dis. 2017 Dec 28;11(12):e0006104. doi: 10.1371/journal.pntd.0006104. eCollection 2017 Dec.


Sterol methyltransferase a target for anti-amoeba therapy: towards transition state analog and suicide substrate drug design.

Kidane ME, Vanderloop BH, Zhou W, Thomas CD, Ramos E, Singha U, Chaudhuri M, Nes WD.

J Lipid Res. 2017 Dec;58(12):2310-2323. doi: 10.1194/jlr.M079418. Epub 2017 Oct 17.


Inhibition of Arabidopsis chloroplast β-amylase BAM3 by maltotriose suggests a mechanism for the control of transitory leaf starch mobilisation.

Li J, Zhou W, Francisco P, Wong R, Zhang D, Smith SM.

PLoS One. 2017 Feb 22;12(2):e0172504. doi: 10.1371/journal.pone.0172504. eCollection 2017.


Sterols indicate water quality and wastewater treatment efficiency.

Reichwaldt ES, Ho WY, Zhou W, Ghadouani A.

Water Res. 2017 Jan 1;108:401-411. doi: 10.1016/j.watres.2016.11.029. Epub 2016 Nov 8.


A systems biology approach toward understanding seed composition in soybean.

Li L, Hur M, Lee JY, Zhou W, Song Z, Ransom N, Demirkale CY, Nettleton D, Westgate M, Arendsee Z, Iyer V, Shanks J, Nikolau B, Wurtele ES.

BMC Genomics. 2015;16 Suppl 3:S9. doi: 10.1186/1471-2164-16-S3-S9. Epub 2015 Jan 29.


Regulation of the cholesterol biosynthetic pathway and its integration with fatty acid biosynthesis in the oleaginous microalga Nannochloropsis oceanica.

Lu Y, Zhou W, Wei L, Li J, Jia J, Li F, Smith SM, Xu J.

Biotechnol Biofuels. 2014 May 30;7:81. doi: 10.1186/1754-6834-7-81. eCollection 2014.


The genetic dissection of a short-term response to low CO(2) supports the possibility for peroxide-mediated decarboxylation of photorespiratory intermediates in the peroxisome.

Keech O, Zhou W, Fenske R, Colas-des-Francs-Small C, Bussell JD, Badger MR, Smith SM.

Mol Plant. 2012 Nov;5(6):1413-6. doi: 10.1093/mp/sss104. Epub 2012 Sep 30. No abstract available.


Differential molecular responses of rice and wheat coleoptiles to anoxia reveal novel metabolic adaptations in amino acid metabolism for tissue tolerance.

Shingaki-Wells RN, Huang S, Taylor NL, Carroll AJ, Zhou W, Millar AH.

Plant Physiol. 2011 Aug;156(4):1706-24. doi: 10.1104/pp.111.175570. Epub 2011 May 27.


Silencing of soybean seed storage proteins results in a rebalanced protein composition preserving seed protein content without major collateral changes in the metabolome and transcriptome.

Schmidt MA, Barbazuk WB, Sandford M, May G, Song Z, Zhou W, Nikolau BJ, Herman EM.

Plant Physiol. 2011 May;156(1):330-45. doi: 10.1104/pp.111.173807. Epub 2011 Mar 10.


Testicular Sertoli cells influence the proliferation and immunogenicity of co-cultured endothelial cells.

Fan P, He L, Pu D, Lv X, Zhou W, Sun Y, Hu N.

Biochem Biophys Res Commun. 2011 Jan 21;404(3):829-33. doi: 10.1016/j.bbrc.2010.12.068. Epub 2010 Dec 21.


Signaling from the endoplasmic reticulum activates brassinosteroid signaling and promotes acclimation to stress in Arabidopsis.

Che P, Bussell JD, Zhou W, Estavillo GM, Pogson BJ, Smith SM.

Sci Signal. 2010 Sep 28;3(141):ra69. doi: 10.1126/scisignal.2001140.


Arabidopsis has a cytosolic fumarase required for the massive allocation of photosynthate into fumaric acid and for rapid plant growth on high nitrogen.

Pracharoenwattana I, Zhou W, Keech O, Francisco PB, Udomchalothorn T, Tschoep H, Stitt M, Gibon Y, Smith SM.

Plant J. 2010 Jun 1;62(5):785-95. doi: 10.1111/j.1365-313X.2010.04189.x. Epub 2010 Feb 26.


Fatty acid beta-oxidation in germinating Arabidopsis seeds is supported by peroxisomal hydroxypyruvate reductase when malate dehydrogenase is absent.

Pracharoenwattana I, Zhou W, Smith SM.

Plant Mol Biol. 2010 Jan;72(1-2):101-9. doi: 10.1007/s11103-009-9554-2. Epub 2009 Oct 8.


Catalytically-inactive beta-amylase BAM4 required for starch breakdown in Arabidopsis leaves is a starch-binding-protein.

Li J, Francisco P, Zhou W, Edner C, Steup M, Ritte G, Bond CS, Smith SM.

Arch Biochem Biophys. 2009 Sep;489(1-2):92-8. doi: 10.1016/ Epub 2009 Aug 5.


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