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Items: 1 to 20 of 49

1.

Integrative analysis of prognostic biomarkers derived from multiomics panels helps discrimination of chronic kidney disease trajectories in people with type 2 diabetes.

Kammer M, Heinzel A, Willency JA, Duffin KL, Mayer G, Simons K, Gerl MJ, Klose C, Heinze G, Reindl-Schwaighofer R, Hu K, Perco P, Eder S, Rosivall L, Mark PB, Ju W, Kretzler M, McCarthy MI, Heerspink HL, Wiecek A, Gomez MF, Oberbauer R; BEAt-DKD Consortium.

Kidney Int. 2019 Dec;96(6):1381-1388. doi: 10.1016/j.kint.2019.07.025. Epub 2019 Aug 30.

PMID:
31679767
2.

Urinary Epidermal Growth Factor/Creatinine Ratio and Graft Failure in Renal Transplant Recipients: A Prospective Cohort Study.

Yepes-Calderón M, Sotomayor CG, Kretzler M, Gans ROB, Berger SP, Navis GJ, Ju W, Bakker SJL.

J Clin Med. 2019 Oct 13;8(10). pii: E1673. doi: 10.3390/jcm8101673.

3.

Identification of dicarbonyl and L-xylulose reductase as a therapeutic target in human chronic kidney disease.

Perco P, Ju W, Kerschbaum J, Leierer J, Menon R, Zhu C, Kretzler M, Mayer G, Rudnicki M; Nephrotic Syndrome Study Network (NEPTUNE).

JCI Insight. 2019 Jun 20;4(12). pii: 128120. doi: 10.1172/jci.insight.128120. eCollection 2019 Jun 20.

4.

Low levels of urinary epidermal growth factor predict chronic kidney disease progression in children.

Azukaitis K, Ju W, Kirchner M, Nair V, Smith M, Fang Z, Thurn-Valsassina D, Bayazit A, Niemirska A, Canpolat N, Bulut IK, Yalcinkaya F, Paripovic D, Harambat J, Cakar N, Alpay H, Lugani F, Mencarelli F, Civilibal M, Erdogan H, Gellermann J, Vidal E, Tabel Y, Gimpel C, Ertan P, Yavascan O, Melk A, Querfeld U, Wühl E, Kretzler M, Schaefer F; 4C Study; ESCAPE Trial Group.

Kidney Int. 2019 Jul;96(1):214-221. doi: 10.1016/j.kint.2019.01.035. Epub 2019 Mar 20.

PMID:
31005273
5.

LRG1 Promotes Diabetic Kidney Disease Progression by Enhancing TGF-β-Induced Angiogenesis.

Hong Q, Zhang L, Fu J, Verghese DA, Chauhan K, Nadkarni GN, Li Z, Ju W, Kretzler M, Cai GY, Chen XM, D'Agati VD, Coca SG, Schlondorff D, He JC, Lee K.

J Am Soc Nephrol. 2019 Apr;30(4):546-562. doi: 10.1681/ASN.2018060599. Epub 2019 Mar 11.

PMID:
30858225
6.

Gene Expression Studies and Targeted Metabolomics Reveal Disturbed Serine, Methionine, and Tyrosine Metabolism in Early Hypertensive Nephrosclerosis.

Øvrehus MA, Bruheim P, Ju W, Zelnick LR, Langlo KA, Sharma K, de Boer IH, Hallan SI.

Kidney Int Rep. 2018 Oct 17;4(2):321-333. doi: 10.1016/j.ekir.2018.10.007. eCollection 2019 Feb.

7.

Tyro3 is a podocyte protective factor in glomerular disease.

Zhong F, Chen Z, Zhang L, Xie Y, Nair V, Ju W, Kretzler M, Nelson RG, Li Z, Chen H, Wang Y, Zhang A, Lee K, Liu Z, He JC.

JCI Insight. 2018 Nov 15;3(22). pii: 123482. doi: 10.1172/jci.insight.123482.

8.

An integrative systems biology approach for precision medicine in diabetic kidney disease.

Mulder S, Hamidi H, Kretzler M, Ju W.

Diabetes Obes Metab. 2018 Oct;20 Suppl 3:6-13. doi: 10.1111/dom.13416. Review.

9.

Validation of Plasma Biomarker Candidates for the Prediction of eGFR Decline in Patients With Type 2 Diabetes.

Heinzel A, Kammer M, Mayer G, Reindl-Schwaighofer R, Hu K, Perco P, Eder S, Rosivall L, Mark PB, Ju W, Kretzler M, Gilmour P, Wilson JM, Duffin KL, Abdalla M, McCarthy MI, Heinze G, Heerspink HL, Wiecek A, Gomez MF, Oberbauer R; BEAt-DKD Consortium.

Diabetes Care. 2018 Sep;41(9):1947-1954. doi: 10.2337/dc18-0532. Epub 2018 Jul 6.

10.

Urinary epidermal growth factor as a prognostic marker for the progression of Alport syndrome in children.

Li B, Zhang Y, Wang F, Nair V, Ding F, Xiao H, Yao Y, Kretzler M, Ju W, Ding J.

Pediatr Nephrol. 2018 Oct;33(10):1731-1739. doi: 10.1007/s00467-018-3988-1. Epub 2018 Jun 11.

11.

GDF-15, Galectin 3, Soluble ST2, and Risk of Mortality and Cardiovascular Events in CKD.

Tuegel C, Katz R, Alam M, Bhat Z, Bellovich K, de Boer I, Brosius F, Gadegbeku C, Gipson D, Hawkins J, Himmelfarb J, Ju W, Kestenbaum B, Kretzler M, Robinson-Cohen C, Steigerwalt S, Bansal N.

Am J Kidney Dis. 2018 Oct;72(4):519-528. doi: 10.1053/j.ajkd.2018.03.025. Epub 2018 Jun 14.

12.

Metabolic pathways and immunometabolism in rare kidney diseases.

Grayson PC, Eddy S, Taroni JN, Lightfoot YL, Mariani L, Parikh H, Lindenmeyer MT, Ju W, Greene CS, Godfrey B, Cohen CD, Krischer J, Kretzler M, Merkel PA; Vasculitis Clinical Research Consortium, the European Renal cDNA Bank cohort, and the Nephrotic Syndrome Study Network.

Ann Rheum Dis. 2018 Aug;77(8):1226-1233. doi: 10.1136/annrheumdis-2017-212935. Epub 2018 May 3.

13.

The Promise of Systems Biology for Diabetic Kidney Disease.

Brosius FC, Ju W.

Adv Chronic Kidney Dis. 2018 Mar;25(2):202-213. doi: 10.1053/j.ackd.2017.10.012. Review.

14.

ORAI channels are critical for receptor-mediated endocytosis of albumin.

Zeng B, Chen GL, Garcia-Vaz E, Bhandari S, Daskoulidou N, Berglund LM, Jiang H, Hallett T, Zhou LP, Huang L, Xu ZH, Nair V, Nelson RG, Ju W, Kretzler M, Atkin SL, Gomez MF, Xu SZ.

Nat Commun. 2017 Dec 4;8(1):1920. doi: 10.1038/s41467-017-02094-y.

15.

Metabolomics and Gene Expression Analysis Reveal Down-regulation of the Citric Acid (TCA) Cycle in Non-diabetic CKD Patients.

Hallan S, Afkarian M, Zelnick LR, Kestenbaum B, Sharma S, Saito R, Darshi M, Barding G, Raftery D, Ju W, Kretzler M, Sharma K, de Boer IH.

EBioMedicine. 2017 Dec;26:68-77. doi: 10.1016/j.ebiom.2017.10.027. Epub 2017 Oct 31.

16.

A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome.

Nair V, Komorowsky CV, Weil EJ, Yee B, Hodgin J, Harder JL, Godfrey B, Ju W, Boustany-Kari CM, Schwarz M, Lemley KV, Nelson PJ, Nelson RG, Kretzler M.

Kidney Int. 2018 Feb;93(2):439-449. doi: 10.1016/j.kint.2017.08.013. Epub 2017 Oct 18.

17.

Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy.

Liu P, Lassén E, Nair V, Berthier CC, Suguro M, Sihlbom C, Kretzler M, Betsholtz C, Haraldsson B, Ju W, Ebefors K, Nyström J.

J Am Soc Nephrol. 2017 Oct;28(10):2961-2972. doi: 10.1681/ASN.2016101103. Epub 2017 Jun 23.

18.

Growth Differentiation Factor-15 and Risk of CKD Progression.

Nair V, Robinson-Cohen C, Smith MR, Bellovich KA, Bhat ZY, Bobadilla M, Brosius F, de Boer IH, Essioux L, Formentini I, Gadegbeku CA, Gipson D, Hawkins J, Himmelfarb J, Kestenbaum B, Kretzler M, Magnone MC, Perumal K, Steigerwalt S, Ju W, Bansal N.

J Am Soc Nephrol. 2017 Jul;28(7):2233-2240. doi: 10.1681/ASN.2016080919. Epub 2017 Feb 3.

19.

Systems biology analysis reveals role of MDM2 in diabetic nephropathy.

Saito R, Rocanin-Arjo A, You YH, Darshi M, Van Espen B, Miyamoto S, Pham J, Pu M, Romoli S, Natarajan L, Ju W, Kretzler M, Nelson R, Ono K, Thomasova D, Mulay SR, Ideker T, D'Agati V, Beyret E, Belmonte JCI, Anders HJ, Sharma K.

JCI Insight. 2016 Oct 20;1(17):e87877. doi: 10.1172/jci.insight.87877.

20.

The Prediction of Key Cytoskeleton Components Involved in Glomerular Diseases Based on a Protein-Protein Interaction Network.

Ding F, Tan A, Ju W, Li X, Li S, Ding J.

PLoS One. 2016 May 26;11(5):e0156024. doi: 10.1371/journal.pone.0156024. eCollection 2016.

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