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Items: 20


Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers.

Hashimoto H, Wang Z, Garry GA, Malladi VS, Botten GA, Ye W, Zhou H, Osterwalder M, Dickel DE, Visel A, Liu N, Bassel-Duby R, Olson EN.

Cell Stem Cell. 2019 Jul 3;25(1):69-86.e5. doi: 10.1016/j.stem.2019.03.022. Epub 2019 May 9.


ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression.

Zhou H, Morales MG, Hashimoto H, Dickson ME, Song K, Ye W, Kim MS, Niederstrasser H, Wang Z, Chen B, Posner BA, Bassel-Duby R, Olson EN.

Genes Dev. 2017 Sep 1;31(17):1770-1783. doi: 10.1101/gad.305482.117.


MED12 regulates a transcriptional network of calcium-handling genes in the heart.

Baskin KK, Makarewich CA, DeLeon SM, Ye W, Chen B, Beetz N, Schrewe H, Bassel-Duby R, Olson EN.

JCI Insight. 2017 Jul 20;2(14). pii: 91920. doi: 10.1172/jci.insight.91920. eCollection 2017 Jul 20.


A unique stylopod patterning mechanism by Shox2-controlled osteogenesis.

Ye W, Song Y, Huang Z, Osterwalder M, Ljubojevic A, Xu J, Bobick B, Abassah-Oppong S, Ruan N, Shamby R, Yu D, Zhang L, Cai CL, Visel A, Zhang Y, Cobb J, Chen Y.

Development. 2016 Jul 15;143(14):2548-60. doi: 10.1242/dev.138750. Epub 2016 Jun 10.


Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole.

Ye W, Song Y, Huang Z, Zhang Y, Chen Y.

J Cardiovasc Dev Dis. 2015 Dec;2(4):282-298. Epub 2015 Nov 30.


Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice.

Yang L, Gu S, Ye W, Song Y, Chen Y.

Cell Tissue Res. 2016 Apr;364(1):105-15. doi: 10.1007/s00441-015-2306-5. Epub 2015 Nov 9.


Altered FGF Signaling Pathways Impair Cell Proliferation and Elevation of Palate Shelves.

Wu W, Gu S, Sun C, He W, Xie X, Li X, Ye W, Qin C, Chen Y, Xiao J, Liu C.

PLoS One. 2015 Sep 2;10(9):e0136951. doi: 10.1371/journal.pone.0136951. eCollection 2015.


FGF8 signaling sustains progenitor status and multipotency of cranial neural crest-derived mesenchymal cells in vivo and in vitro.

Shao M, Liu C, Song Y, Ye W, He W, Yuan G, Gu S, Lin C, Ma L, Zhang Y, Tian W, Hu T, Chen Y.

J Mol Cell Biol. 2015 Oct;7(5):441-54. doi: 10.1093/jmcb/mjv052. Epub 2015 Aug 4.


A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node.

Ye W, Wang J, Song Y, Yu D, Sun C, Liu C, Chen F, Zhang Y, Wang F, Harvey RP, Schrader L, Martin JF, Chen Y.

Development. 2015 Jul 15;142(14):2521-32. doi: 10.1242/dev.120220. Epub 2015 Jul 2.


The short stature homeobox 2 (Shox2)-bone morphogenetic protein (BMP) pathway regulates dorsal mesenchymal protrusion development and its temporary function as a pacemaker during cardiogenesis.

Sun C, Yu D, Ye W, Liu C, Gu S, Sinsheimer NR, Song Z, Li X, Chen C, Song Y, Wang S, Schrader L, Chen Y.

J Biol Chem. 2015 Jan 23;290(4):2007-23. doi: 10.1074/jbc.M114.619007. Epub 2014 Dec 8.


An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis.

Yang G, Yuan G, Ye W, Cho KW, Chen Y.

J Biol Chem. 2014 Nov 7;289(45):31492-502. doi: 10.1074/jbc.M114.600064. Epub 2014 Oct 1.


BMPRIA mediated signaling is essential for temporomandibular joint development in mice.

Gu S, Wu W, Liu C, Yang L, Sun C, Ye W, Li X, Chen J, Long F, Chen Y.

PLoS One. 2014 Aug 5;9(8):e101000. doi: 10.1371/journal.pone.0101000. eCollection 2014.


Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation.

Wang J, Bai Y, Li N, Ye W, Zhang M, Greene SB, Tao Y, Chen Y, Wehrens XH, Martin JF.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9181-6. doi: 10.1073/pnas.1405411111. Epub 2014 Jun 10.


Phosphorylation of Shox2 is required for its function to control sinoatrial node formation.

Liu H, Chen CH, Ye W, Espinoza-Lewis RA, Hu X, Zhang Y, Chen Y.

J Am Heart Assoc. 2014 May 20;3(3):e000796. doi: 10.1161/JAHA.114.000796.


FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling.

Liu C, Gu S, Sun C, Ye W, Song Z, Zhang Y, Chen Y.

Development. 2013 Nov;140(21):4375-85. doi: 10.1242/dev.097733. Epub 2013 Sep 25.


Nuclear import of aristaless-related homeobox protein via its NLS1 regulates its transcriptional function.

Ye W, Lin W, Tartakoff AM, Ma Q, Tao T.

Mol Cell Biochem. 2013 Sep;381(1-2):221-31. doi: 10.1007/s11010-013-1706-7. Epub 2013 Jun 16.


Karyopherins in nuclear transport of homeodomain proteins during development.

Ye W, Lin W, Tartakoff AM, Tao T.

Biochim Biophys Acta. 2011 Sep;1813(9):1654-62. doi: 10.1016/j.bbamcr.2011.01.013. Epub 2011 Jan 20. Review.


The roles of multiple importins for nuclear import of murine aristaless-related homeobox protein.

Lin W, Ye W, Cai L, Meng X, Ke G, Huang C, Peng Z, Yu Y, Golden JA, Tartakoff AM, Tao T.

J Biol Chem. 2009 Jul 24;284(30):20428-39. doi: 10.1074/jbc.M109.004242. Epub 2009 Jun 3.


ARHI (DIRAS3), an imprinted tumour suppressor gene, binds to importins and blocks nuclear import of cargo proteins.

Huang S, Chang IS, Lin W, Ye W, Luo RZ, Lu Z, Lu Y, Zhang K, Liao WS, Tao T, Bast RC Jr, Chen X, Yu Y.

Biosci Rep. 2009 Dec 15;30(3):159-68. doi: 10.1042/BSR20090008.

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