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Items: 1 to 20 of 103


GABA and glycine neurons from the ventral medullary region inhibit hypoglossal motoneurons.

Dergacheva O, Fleury-Curado T, Polotsky VY, Kay M, Jain V, Mendelowitz D.

Sleep. 2019 Dec 13. pii: zsz301. doi: 10.1093/sleep/zsz301. [Epub ahead of print]


The Role of Animal Models in Developing Pharmacotherapy for Obstructive Sleep Apnea.

Kim LJ, Freire C, Fleury Curado T, Jun JC, Polotsky VY.

J Clin Med. 2019 Nov 22;8(12). pii: E2049. doi: 10.3390/jcm8122049. Review.


Experimental Approach to Examine Leptin Signaling in the Carotid Bodies and its Effects on Control of Breathing.

Shin MK, Kim LJ, Caballero-Eraso C, Polotsky VY.

J Vis Exp. 2019 Oct 25;(152). doi: 10.3791/60298.


Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.

Shin MK, Eraso CC, Mu YP, Gu C, Yeung BHY, Kim LJ, Liu XR, Wu ZJ, Paudel O, Pichard LE, Shirahata M, Tang WY, Sham JSK, Polotsky VY.

Circ Res. 2019 Nov 8;125(11):989-1002. doi: 10.1161/CIRCRESAHA.119.315338. Epub 2019 Sep 23.


Obstructive sleep apnoea and susceptibility to cardiovascular disease: A blessing or curse of old age?

Jun JC, Polotsky VY.

Respirology. 2019 Aug 14. doi: 10.1111/resp.13679. [Epub ahead of print] No abstract available.


Upright posture increases oxyhemoglobin saturation in Peruvian highlanders.

Arias RS, Etienne B, Polotsky VY, Checkley W, Schwartz AR, Pham LV.

Respir Physiol Neurobiol. 2019 Aug;266:138-143. doi: 10.1016/j.resp.2019.04.015. Epub 2019 May 24.


Caloric restriction prevents the development of airway hyperresponsiveness in mice on a high fat diet.

Younas H, Vieira M, Gu C, Lee R, Shin MK, Berger S, Loube J, Nelson A, Bevans-Fonti S, Zhong Q, D'Alessio FR, McCormack MC, Hansel NN, Mitzner W, Polotsky VY.

Sci Rep. 2019 Jan 22;9(1):279. doi: 10.1038/s41598-018-36651-2.


Vertical sleeve gastrectomy improves ventilatory drive through a leptin-dependent mechanism.

Arble DM, Schwartz AR, Polotsky VY, Sandoval DA, Seeley RJ.

JCI Insight. 2019 Jan 10;4(1). pii: 124469. doi: 10.1172/jci.insight.124469. [Epub ahead of print]


A Novel Non-invasive Approach for Measuring Upper Airway Collapsibility in Mice.

Nishimura Y, Arias RS, Pho H, Pham LV, Curado TF, Polotsky VY, Schwartz AR.

Front Neurol. 2018 Nov 20;9:985. doi: 10.3389/fneur.2018.00985. eCollection 2018.


Pharmacotherapy of Obstructive Sleep Apnea: Is Salvation Just Around a Corner?

Fleury Curado T, Berger S, Polotsky VY.

Am J Respir Crit Care Med. 2019 May 15;199(10):1186-1187. doi: 10.1164/rccm.201811-2135ED. No abstract available.


Silencing of Hypoglossal Motoneurons Leads to Sleep Disordered Breathing in Lean Mice.

Fleury Curado TA, Pho H, Dergacheva O, Berger S, Lee R, Freire C, Asherov A, Sennes LU, Mendelowitz D, Schwartz AR, Polotsky VY.

Front Neurol. 2018 Nov 14;9:962. doi: 10.3389/fneur.2018.00962. eCollection 2018.


Intranasal Leptin Relieves Sleep-disordered Breathing in Mice with Diet-induced Obesity.

Berger S, Pho H, Fleury-Curado T, Bevans-Fonti S, Younas H, Shin MK, Jun JC, Anokye-Danso F, Ahima RS, Enquist LW, Mendelowitz D, Schwartz AR, Polotsky VY.

Am J Respir Crit Care Med. 2019 Mar 15;199(6):773-783. doi: 10.1164/rccm.201805-0879OC.


Leptin acts in the carotid bodies to increase minute ventilation during wakefulness and sleep and augment the hypoxic ventilatory response.

Caballero-Eraso C, Shin MK, Pho H, Kim LJ, Pichard LE, Wu ZJ, Gu C, Berger S, Pham L, Yeung HB, Shirahata M, Schwartz AR, Tang WW, Sham JSK, Polotsky VY.

J Physiol. 2019 Jan;597(1):151-172. doi: 10.1113/JP276900. Epub 2018 Nov 29.


Neurostimulation Treatment of OSA.

Fleury Curado T, Oliven A, Sennes LU, Polotsky VY, Eisele D, Schwartz AR.

Chest. 2018 Dec;154(6):1435-1447. doi: 10.1016/j.chest.2018.08.1070. Epub 2018 Sep 14. Review.


Integrating loop gain into the understanding of obstructive sleep apnoea mechanisms.

Pham LV, Schwartz AR, Polotsky VY.

J Physiol. 2018 Sep;596(17):3819-3820. doi: 10.1113/JP276590. Epub 2018 Jul 23. No abstract available.


Sleep-disordered breathing in C57BL/6J mice with diet-induced obesity.

Fleury Curado T, Pho H, Berger S, Caballero-Eraso C, Shin MK, Sennes LU, Pham L, Schwartz AR, Polotsky VY.

Sleep. 2018 Aug 1;41(8). doi: 10.1093/sleep/zsy089.


High fat diet induces airway hyperresponsiveness in mice.

Fricke K, Vieira M, Younas H, Shin MK, Bevans-Fonti S, Berger S, Lee R, D'Alessio FR, Zhong Q, Nelson A, Loube J, Sanchez I, Hansel NN, Mitzner W, Polotsky VY.

Sci Rep. 2018 Apr 23;8(1):6404. doi: 10.1038/s41598-018-24759-4.


Leptin and Leptin Resistance in the Pathogenesis of Obstructive Sleep Apnea: A Possible Link to Oxidative Stress and Cardiovascular Complications.

Berger S, Polotsky VY.

Oxid Med Cell Longev. 2018 Feb 20;2018:5137947. doi: 10.1155/2018/5137947. eCollection 2018. Review.


Obstructive sleep apnea and effects of continuous positive airway pressure on triglyceride-rich lipoprotein metabolism.

Drager LF, Tavoni TM, Silva VM, Santos RD, Pedrosa RP, Bortolotto LA, Vinagre CG, Polotsky VY, Lorenzi-Filho G, Maranhao RC.

J Lipid Res. 2018 Jun;59(6):1027-1033. doi: 10.1194/jlr.M083436. Epub 2018 Apr 8.


Disturbed sleep and diabetes: A potential nexus of dementia risk.

Holingue C, Wennberg A, Berger S, Polotsky VY, Spira AP.

Metabolism. 2018 Jul;84:85-93. doi: 10.1016/j.metabol.2018.01.021. Epub 2018 Feb 1. Review.

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