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Items: 16

1.

Hypoxia Modulates Effects of Fatty Acids on NES2Y Human Pancreatic β-cells.

Šrámek J, Němcová-Fürstová V, Polák J, Kovář J.

Int J Mol Sci. 2019 Jul 12;20(14). pii: E3441. doi: 10.3390/ijms20143441.

2.

Stearate-Induced Apoptosis in Human Pancreatic β-Cells is Associated with Changes in Membrane Protein Expression and These Changes are Inhibited by Oleate.

Němcová-Fürstová V, Balušíková K, Halada P, Pavlíková N, Šrámek J, Kovář J.

Proteomics Clin Appl. 2019 Jul;13(4):e1800104. doi: 10.1002/prca.201800104. Epub 2019 Jan 31.

PMID:
30666801
3.

Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel.

Jelínek M, Balušíková K, Daniel P, Němcová-Fürstová V, Kirubakaran P, Jaček M, Wei L, Wang X, Vondrášek J, Ojima I, Kovář J.

Toxicol Appl Pharmacol. 2018 May 15;347:79-91. doi: 10.1016/j.taap.2018.04.002. Epub 2018 Apr 4.

4.

Effect of Saturated Stearic Acid on MAP Kinase and ER Stress Signaling Pathways during Apoptosis Induction in Human Pancreatic β-Cells Is Inhibited by Unsaturated Oleic Acid.

Šrámek J, Němcová-Fürstová V, Pavlíková N, Kovář J.

Int J Mol Sci. 2017 Nov 2;18(11). pii: E2313. doi: 10.3390/ijms18112313.

5.

Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients.

Brynychova V, Ehrlichova M, Hlavac V, Nemcova-Furstova V, Pecha V, Leva J, Trnkova M, Mrhalova M, Kodet R, Vrana D, Kovar J, Vaclavikova R, Gut I, Soucek P.

Biomed Pharmacother. 2016 Oct;83:857-864. doi: 10.1016/j.biopha.2016.07.047. Epub 2016 Aug 6.

PMID:
27505863
6.

Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters.

Němcová-Fürstová V, Kopperová D, Balušíková K, Ehrlichová M, Brynychová V, Václavíková R, Daniel P, Souček P, Kovář J.

Toxicol Appl Pharmacol. 2016 Nov 1;310:215-228. doi: 10.1016/j.taap.2016.09.020. Epub 2016 Sep 21.

PMID:
27664577
7.

Kinase Signaling in Apoptosis Induced by Saturated Fatty Acids in Pancreatic β-Cells.

Šrámek J, Němcová-Fürstová V, Kovář J.

Int J Mol Sci. 2016 Sep 12;17(9). pii: E1400. doi: 10.3390/ijms17091400. Review.

8.

Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target.

Brynychova V, Hlavac V, Ehrlichova M, Vaclavikova R, Nemcova-Furstova V, Pecha V, Trnkova M, Mrhalova M, Kodet R, Vrana D, Gatek J, Bendova M, Vernerova Z, Kovar J, Soucek P.

Clin Chem Lab Med. 2017 Jan 1;55(1):111-122. doi: 10.1515/cclm-2016-0271.

PMID:
27327132
9.

p38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells.

Šrámek J, Němcová-Fürstová V, Balušíková K, Daniel P, Jelínek M, James RF, Kovář J.

Int J Mol Sci. 2016 Feb 5;17(2):159. doi: 10.3390/ijms17020159.

10.

Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness.

Jiroutková K, Krajčová A, Ziak J, Fric M, Waldauf P, Džupa V, Gojda J, Němcova-Fürstová V, Kovář J, Elkalaf M, Trnka J, Duška F.

Crit Care. 2015 Dec 24;19:448. doi: 10.1186/s13054-015-1160-x.

11.

The role of individual caspases in cell death induction by taxanes in breast cancer cells.

Jelínek M, Balušíková K, Schmiedlová M, Němcová-Fürstová V, Šrámek J, Stančíková J, Zanardi I, Ojima I, Kovář J.

Cancer Cell Int. 2015 Feb 4;15(1):8. doi: 10.1186/s12935-015-0155-7. eCollection 2015.

12.

Caspase-2 is involved in cell death induction by taxanes in breast cancer cells.

Jelínek M, Balušíková K, Kopperová D, Nĕmcová-Fürstová V, Šrámek J, Fidlerová J, Zanardi I, Ojima I, Kovář J.

Cancer Cell Int. 2013 May 15;13(1):42. doi: 10.1186/1475-2867-13-42.

13.

Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells.

Němcová-Fürstová V, Balušíková K, Srámek J, James RF, Kovář J.

Cell Physiol Biochem. 2013;31(2-3):277-89. doi: 10.1159/000343367. Epub 2013 Feb 28.

14.

Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ADR-RES cells.

Ehrlichová M, Ojima I, Chen J, Václavíková R, Němcová-Fürstová V, Vobořilová J, Simek P, Horský S, Souček P, Kovář J, Brabec M, Gut I.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Oct;385(10):1035-48. doi: 10.1007/s00210-012-0785-4. Epub 2012 Aug 2.

PMID:
22855252
15.

Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction.

Němcová-Fürstová V, James RF, Kovář J.

Cell Physiol Biochem. 2011;27(5):525-38. doi: 10.1159/000329954. Epub 2011 Jun 15.

16.

Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells.

Vobořilová J, Němcová-Fürstová V, Neubauerová J, Ojima I, Zanardi I, Gut I, Kovář J.

Invest New Drugs. 2011 Jun;29(3):411-23. doi: 10.1007/s10637-009-9368-8. Epub 2009 Dec 16.

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