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Items: 20


Universal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana.

Makhema J, Wirth KE, Pretorius Holme M, Gaolathe T, Mmalane M, Kadima E, Chakalisa U, Bennett K, Leidner J, Manyake K, Mbikiwa AM, Simon SV, Letlhogile R, Mukokomani K, van Widenfelt E, Moyo S, Lebelonyane R, Alwano MG, Powis KM, Dryden-Peterson SL, Kgathi C, Novitsky V, Moore J, Bachanas P, Abrams W, Block L, El-Halabi S, Marukutira T, Mills LA, Sexton C, Raizes E, Gaseitsiwe S, Bussmann H, Okui L, John O, Shapiro RL, Pals S, Michael H, Roland M, DeGruttola V, Lei Q, Wang R, Tchetgen Tchetgen E, Essex M, Lockman S.

N Engl J Med. 2019 Jul 18;381(3):230-242. doi: 10.1056/NEJMoa1812281.


Low rates of nucleoside reverse transcriptase inhibitor and nonnucleoside reverse transcriptase inhibitor drug resistance in Botswana.

Moyo S, Gaseitsiwe S, Zahralban-Steele M, Maruapula D, Nkhisang T, Mokaleng B, Mohammed T, Ditlhako TR, Bareng OT, Mokgethi TP, van Widenfelt E, Pretorius-Holme M, Mine MO, Raizes E, Yankinda EK, Wirth KE, Gaolathe T, Makhema JM, Lockman S, Essex M, Novitsky V.

AIDS. 2019 May 1;33(6):1073-1082. doi: 10.1097/QAD.0000000000002166.


Global and regional molecular epidemiology of HIV-1, 1990-2015: a systematic review, global survey, and trend analysis.

Hemelaar J, Elangovan R, Yun J, Dickson-Tetteh L, Fleminger I, Kirtley S, Williams B, Gouws-Williams E, Ghys PD; WHO–UNAIDS Network for HIV Isolation Characterisation.

Lancet Infect Dis. 2019 Feb;19(2):143-155. doi: 10.1016/S1473-3099(18)30647-9. Epub 2018 Nov 30. Erratum in: Lancet Infect Dis. 2020 Mar;20(3):e27.


Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015.

Moyo S, Gaseitsiwe S, Mohammed T, Pretorius Holme M, Wang R, Kotokwe KP, Boleo C, Mupfumi L, Yankinda EK, Chakalisa U, van Widenfelt E, Gaolathe T, Mmalane MO, Dryden-Peterson S, Mine M, Lebelonyane R, Bennett K, Leidner J, Wirth KE, Tchetgen Tchetgen E, Powis K, Moore J, Clarke WA, Lockman S, Makhema JM, Essex M, Novitsky V.

PLoS One. 2018 Oct 24;13(10):e0204840. doi: 10.1371/journal.pone.0204840. eCollection 2018.


Lack of Virological Suppression Among Young HIV-Positive Adults in Botswana.

Novitsky V, Gaolathe T, Mmalane M, Moyo S, Chakalisa U, Yankinda EK, Marukutira T, Holme MP, Sekoto T, Gaseitsiwe S, Musonda R, van Widenfelt E, Powis KM, Khan N, Dryden-Peterson S, Bennett K, Wirth KE, Tchetgen ET, Bachanas P, Mills LA, Lebelonyane R, El-Halabi S, Makhema J, Lockman S, Essex M.

J Acquir Immune Defic Syndr. 2018 Aug 15;78(5):557-565. doi: 10.1097/QAI.0000000000001715.


Undisclosed antiretroviral drug use in Botswana: implication for national estimates.

Moyo S, Gaseitsiwe S, Powis KM, Pretorius Holme M, Mohammed T, Zahralban-Steele M, Yankinde EK, Maphorisa C, Abrams W, Lebelonyane R, Manyake K, Sekoto T, Mmalane M, Gaolathe T, Wirth KE, Makhema J, Lockman S, Clarke W, Essex M, Novitsky V.

AIDS. 2018 Jul 17;32(11):1543-1546. doi: 10.1097/QAD.0000000000001862.


Deciphering Multiplicity of HIV-1C Infection: Transmission of Closely Related Multiple Viral Lineages.

Novitsky V, Moyo S, Wang R, Gaseitsiwe S, Essex M.

PLoS One. 2016 Nov 28;11(11):e0166746. doi: 10.1371/journal.pone.0166746. eCollection 2016.


Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection.

Rossenkhan R, MacLeod IJ, Brumme ZL, Magaret CA, Sebunya TK, Musonda R, Gashe BA, Edlefsen PT, Novitsky V, Essex M.

AIDS Res Hum Retroviruses. 2016 Oct/Nov;32(10-11):1031-1045. Epub 2016 Jul 26.


Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey.

Gaolathe T, Wirth KE, Holme MP, Makhema J, Moyo S, Chakalisa U, Yankinda EK, Lei Q, Mmalane M, Novitsky V, Okui L, van Widenfelt E, Powis KM, Khan N, Bennett K, Bussmann H, Dryden-Peterson S, Lebelonyane R, El-Halabi S, Mills LA, Marukutira T, Wang R, Tchetgen EJ, DeGruttola V, Essex M, Lockman S; Botswana Combination Prevention Project study team.

Lancet HIV. 2016 May;3(5):e221-30. doi: 10.1016/S2352-3018(16)00037-0. Epub 2016 Mar 24.


Correction for Novitsky et al., Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering.

Novitsky V, Zahralban-Steele M, McLane MF, Moyo S, van Widenfelt E, Gaseitsiwe S, Makhema J, Essex M.

J Clin Microbiol. 2016 Apr;54(4):1175. doi: 10.1128/JCM.00190-16. No abstract available.


Phylodynamic analysis of HIV sub-epidemics in Mochudi, Botswana.

Novitsky V, Kühnert D, Moyo S, Widenfelt E, Okui L, Essex M.

Epidemics. 2015 Dec;13:44-55. doi: 10.1016/j.epidem.2015.07.002. Epub 2015 Aug 28.


Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering.

Novitsky V, Zahralban-Steele M, McLane MF, Moyo S, van Widenfelt E, Gaseitsiwe S, Makhema J, Essex M.

J Clin Microbiol. 2015 Aug;53(8):2581-92. doi: 10.1128/JCM.00756-15. Epub 2015 Jun 3. Erratum in: J Clin Microbiol. 2016 Apr;54(4):1175.


Estimated age and gender profile of individuals missed by a home-based HIV testing and counselling campaign in a Botswana community.

Novitsky V, Bussmann H, Okui L, Logan A, Moyo S, van Widenfelt E, Mmalane M, Lei Q, Holme MP, Makhema J, Lockman S, Degruttola V, Essex M.

J Int AIDS Soc. 2015 May 29;18:19918. doi: 10.7448/IAS.18.1.19918. eCollection 2015.


Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering.

Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M.

AIDS Res Hum Retroviruses. 2015 May;31(5):531-42. doi: 10.1089/AID.2014.0211. Epub 2015 Feb 6.


Impact of sampling density on the extent of HIV clustering.

Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M.

AIDS Res Hum Retroviruses. 2014 Dec;30(12):1226-35. doi: 10.1089/aid.2014.0173.


Intra-host evolutionary rates in HIV-1C env and gag during primary infection.

Novitsky V, Wang R, Rossenkhan R, Moyo S, Essex M.

Infect Genet Evol. 2013 Oct;19:361-8. doi: 10.1016/j.meegid.2013.02.023. Epub 2013 Mar 20.


tat Exon 1 exhibits functional diversity during HIV-1 subtype C primary infection.

Rossenkhan R, MacLeod IJ, Sebunya TK, Castro-Nallar E, McLane MF, Musonda R, Gashe BA, Novitsky V, Essex M.

J Virol. 2013 May;87(10):5732-45. doi: 10.1128/JVI.03297-12. Epub 2013 Mar 13.


HIV-1 Subtype C Phylodynamics in the Global Epidemic.

Novitsky V, Wang R, Lagakos S, Essex M.

Viruses. 2010 Jan;2(1):33-54. doi: 10.3390/v2010033. Epub 2010 Jan 7.


The reverse transcriptase 67N 70R 215Y genotype is the predominant TAM pathway associated with virologic failure among HIV type 1C-infected adults treated with ZDV/ddI-containing HAART in southern Africa.

Novitsky V, Wester CW, DeGruttola V, Bussmann H, Gaseitsiwe S, Thomas A, Moyo S, Musonda R, Van Widenfelt E, Marlink RG, Essex M.

AIDS Res Hum Retroviruses. 2007 Jul;23(7):868-78.


Cross-clade reactivity of HIV-1-specific T-cell responses in HIV-1-infected individuals from Botswana and Cameroon.

Gupta SB, Mast CT, Wolfe ND, Novitsky V, Dubey SA, Kallas EG, Schechter M, Mbewe B, Vardas E, Pitisuttithum P, Burke D, Freed D, Mogg R, Coplan PM, Condra JH, Long RS, Anderson K, Casimiro DR, Shiver JW, Straus WL.

J Acquir Immune Defic Syndr. 2006 Jun;42(2):135-9.


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