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Items: 20


Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types.

Greenplate AR, McClanahan DD, Oberholtzer BK, Doxie DB, Roe CE, Diggins KE, Leelatian N, Rasmussen ML, Kelley MC, Gama V, Siska PJ, Rathmell JC, Ferrell PB, Johnson DB, Irish JM.

Cancer Immunol Res. 2019 Jan;7(1):86-99. doi: 10.1158/2326-6066.CIR-17-0692. Epub 2018 Nov 9.


Wnt Signaling and Its Impact on Mitochondrial and Cell Cycle Dynamics in Pluripotent Stem Cells.

Rasmussen ML, Ortolano NA, Romero-Morales AI, Gama V.

Genes (Basel). 2018 Feb 19;9(2). pii: E109. doi: 10.3390/genes9020109. Review.


A Non-apoptotic Function of MCL-1 in Promoting Pluripotency and Modulating Mitochondrial Dynamics in Stem Cells.

Rasmussen ML, Kline LA, Park KP, Ortolano NA, Romero-Morales AI, Anthony CC, Beckermann KE, Gama V.

Stem Cell Reports. 2018 Mar 13;10(3):684-692. doi: 10.1016/j.stemcr.2018.01.005. Epub 2018 Feb 8.


Apical polarization and lumenogenesis: The apicosome sheds new light.

Romero-Morales AI, Ortolano NA, Gama V.

J Cell Biol. 2017 Dec 4;216(12):3891-3893. doi: 10.1083/jcb.201710028. Epub 2017 Nov 14.


Chronicle of a Neuronal Death Foretold: Preventing Aging by Keeping MGRN1 at the Nucleus.

Ortolano NA, Gama V.

Mol Cell. 2017 May 4;66(3):301-303. doi: 10.1016/j.molcel.2017.04.014.


The Molecular Basis for the Lack of Inflammatory Responses in Mouse Embryonic Stem Cells and Their Differentiated Cells.

D'Angelo W, Gurung C, Acharya D, Chen B, Ortolano N, Gama V, Bai F, Guo YL.

J Immunol. 2017 Mar 1;198(5):2147-2155. doi: 10.4049/jimmunol.1601068. Epub 2017 Jan 27.


Life after MOMP.

Gama V, Deshmukh M.

Mol Cell. 2015 Apr 16;58(2):199-201. doi: 10.1016/j.molcel.2015.03.035.


The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.

Gama V, Swahari V, Schafer J, Kole AJ, Evans A, Huang Y, Cliffe A, Golitz B, Sciaky N, Pei XH, Xiong Y, Deshmukh M.

Sci Signal. 2014 Jul 15;7(334):ra67. doi: 10.1126/scisignal.2005309.


Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma.

Crowther AJ, Gama V, Bevilacqua A, Chang SX, Yuan H, Deshmukh M, Gershon TR.

J Neurosci. 2013 Nov 13;33(46):18098-108. doi: 10.1523/JNEUROSCI.2602-13.2013.


Adenosine: essential for life but licensed to kill.

Gama V, Deshmukh M.

Mol Cell. 2013 May 9;50(3):307-8. doi: 10.1016/j.molcel.2013.04.020.


Human embryonic stem cells: living on the edge.

Gama V, Deshmukh M.

Cell Cycle. 2012 Nov 1;11(21):3905-6. doi: 10.4161/cc.22233. Epub 2012 Oct 3. No abstract available.


Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis.

Dumitru R, Gama V, Fagan BM, Bower JJ, Swahari V, Pevny LH, Deshmukh M.

Mol Cell. 2012 Jun 8;46(5):573-83. doi: 10.1016/j.molcel.2012.04.002. Epub 2012 May 3.


Mortalin, apoptosis, and neurodegeneration.

Londono C, Osorio C, Gama V, Alzate O.

Biomolecules. 2012 Mar 1;2(1):143-64. doi: 10.3390/biom2010143.


CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor.

Leskov KS, Araki S, Lavik JP, Gomez JA, Gama V, Gonos ES, Trougakos IP, Matsuyama S, Boothman DA.

J Biol Chem. 2011 Nov 18;286(46):40083-90. doi: 10.1074/jbc.M111.252957. Epub 2011 Sep 27.


Cell-Penetrating Penta-Peptides (CPP5s): Measurement of Cell Entry and Protein-Transduction Activity.

Gomez JA, Chen J, Ngo J, Hajkova D, Yeh IJ, Gama V, Miyagi M, Matsuyama S.

Pharmaceuticals (Basel). 2010 Dec 15;3(12):3594-3613.


The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor.

Gomez JA, Sun W, Gama V, Hajkova D, Yoshida T, Wu Z, Miyagi M, Pink JJ, Jackson MW, Danielpour D, Matsuyama S.

Cancer Biol Ther. 2009 Sep;8(18):1771-86. Epub 2009 Sep 20.


A C-terminal fragment of Cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron.

Plesca D, Mazumder S, Gama V, Matsuyama S, Almasan A.

J Biol Chem. 2008 Nov 7;283(45):30796-803. doi: 10.1074/jbc.M804642200. Epub 2008 Sep 10.


Ku70 is stabilized by increased cellular SUMO.

Yurchenko V, Xue Z, Gama V, Matsuyama S, Sadofsky MJ.

Biochem Biophys Res Commun. 2008 Feb 1;366(1):263-8. Epub 2007 Dec 4.


Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis.

Gama V, Yoshida T, Gomez JA, Basile DP, Mayo LD, Haas AL, Matsuyama S.

Exp Cell Res. 2006 Feb 15;312(4):488-99.


Bax-inhibiting peptide derived from mouse and rat Ku70.

Yoshida T, Tomioka I, Nagahara T, Holyst T, Sawada M, Hayes P, Gama V, Okuno M, Chen Y, Abe Y, Kanouchi T, Sasada H, Wang D, Yokota T, Sato E, Matsuyama S.

Biochem Biophys Res Commun. 2004 Sep 3;321(4):961-6.


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