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New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca2+-Modulating Activity Isolated from Sea Urchin Eggs.

D'Errico S, Basso E, Falanga AP, Marzano M, Pozzan T, Piccialli V, Piccialli G, Oliviero G, Borbone N.

Mar Drugs. 2019 Aug 17;17(8). pii: E476. doi: 10.3390/md17080476.


Smenamide A Analogues. Synthesis and Biological Activity on Multiple Myeloma Cells.

Caso A, Laurenzana I, Lamorte D, Trino S, Esposito G, Piccialli V, Costantino V.

Mar Drugs. 2018 Jun 13;16(6). pii: E206. doi: 10.3390/md16060206.


Crystal structure of an ep-oxy-sterol: 9α,11α-ep-oxy-5α-cholest-7-ene-3β,5,6α-triol 3,6-di-acetate.

Piccialli V, Tuzi A, Centore R.

Acta Crystallogr E Crystallogr Commun. 2017 Oct 6;73(Pt 11):1603-1606. doi: 10.1107/S2056989017013391. eCollection 2017 Nov 1.


Studies toward the Synthesis of Smenamide A, an Antiproliferative Metabolite from Smenospongia aurea: Total Synthesis of ent-Smenamide A and 16-epi-Smenamide A.

Caso A, Mangoni A, Piccialli G, Costantino V, Piccialli V.

ACS Omega. 2017 Apr 30;2(4):1477-1488. doi: 10.1021/acsomega.7b00095. Epub 2017 Apr 17.


5-Amino-1-(2',3'-O-iso-propyl-idene-d-ribit-yl)-1H-imidazole-4-carboxamide: a crystal structure with Z' = 4.

Piccialli V, Borbone N, Oliviero G, Piccialli G, D'Errico S, Centore R.

Acta Crystallogr E Crystallogr Commun. 2017 Jan 13;73(Pt 2):183-187. doi: 10.1107/S2056989017000500. eCollection 2017 Feb 1.


Synthesis and label free characterization of a bimolecular PNA homo quadruplex.

Pinto B, Rusciano G, D'Errico S, Borbone N, Sasso A, Piccialli V, Mayol L, Oliviero G, Piccialli G.

Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1222-1228. doi: 10.1016/j.bbagen.2016.11.037. Epub 2016 Nov 29.


Degradation of some representative polycyclic aromatic hydrocarbons by the water-soluble protein extracts from Zea mays L. cv PR32-B10.

Barone R, de Biasi MG, Piccialli V, de Napoli L, Oliviero G, Borbone N, Piccialli G.

Chemosphere. 2016 Oct;160:258-65. doi: 10.1016/j.chemosphere.2016.06.069. Epub 2016 Jul 6.


Synthesis of cyclic N (1)-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells.

Mahal A, D'Errico S, Borbone N, Pinto B, Secondo A, Costantino V, Tedeschi V, Oliviero G, Piccialli V, Piccialli G.

Beilstein J Org Chem. 2015 Dec 22;11:2689-2695. doi: 10.3762/bjoc.11.289. eCollection 2015.


Synthesis of 5-Aminoimidazole-4-Carboxamide Riboside (AICAR) and Its Derivatives Using Inosine as Starting Material.

D'Errico S, Oliviero G, Borbone N, Piccialli V, Piccialli G.

Curr Protoc Nucleic Acid Chem. 2015 Dec 1;63:1.35.1-1.35.24. doi: 10.1002/0471142700.nc0135s63.


Synthesis and pharmacological evaluation of modified adenosines joined to mono-functional platinum moieties.

D'Errico S, Oliviero G, Borbone N, Piccialli V, Pinto B, De Falco F, Maiuri MC, Carnuccio R, Costantino V, Nici F, Piccialli G.

Molecules. 2014 Jul 3;19(7):9339-53. doi: 10.3390/molecules19079339.


The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells.

Iovine B, Oliviero G, Garofalo M, Orefice M, Nocella F, Borbone N, Piccialli V, Centore R, Mazzone M, Piccialli G, Bevilacqua MA.

PLoS One. 2014 May 7;9(5):e96755. doi: 10.1371/journal.pone.0096755. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e99739. PLoS One. 2014;9(8):e105664.


(3R,3aR,6R,6aR)-Hexa-hydro-furo[3,2-b]furan-3,6-diyl dibenzoate.

Piccialli V, Zaccaria S, Borbone N, Centore R, Tuzi A.

Acta Crystallogr Sect E Struct Rep Online. 2013 Aug 7;69(Pt 9):o1396-7. doi: 10.1107/S1600536813021612. eCollection 2013.


(3S,3aS,6R,6aR)-2-Oxohexa-hydro-furo[3,2-b]furan-3,6-diyl dibenzoate.

Piccialli V, Oliviero G, Zaccaria S, Centore R, Tuzi A.

Acta Crystallogr Sect E Struct Rep Online. 2013 Sep 4;69(Pt 10):o1494-5. doi: 10.1107/S160053681302391X. eCollection 2013.


4,5-Di-amino-3-[(E,E)-4-(4,5-di-amino-4H-1,2,4-triazol-3-yl)buta-1,3-dien-yl]-4H-1,2,4-triazol-1-ium chloride.

Centore R, Piccialli V.

Acta Crystallogr Sect E Struct Rep Online. 2013 Jun 22;69(Pt 7):o1131-2. doi: 10.1107/S1600536813016589. eCollection 2013.



Piccialli V, Tuzi A, Oliviero G, Borbone N, Centore R.

Acta Crystallogr Sect E Struct Rep Online. 2013 Jun 15;69(Pt 7):o1109-10. doi: 10.1107/S1600536813016206. eCollection 2013.


Synthesis of new acadesine (AICA-riboside) analogues having acyclic D-ribityl or 4-hydroxybutyl chains in place of the ribose.

D'Errico S, Oliviero G, Borbone N, Amato J, Piccialli V, Varra M, Mayol L, Piccialli G.

Molecules. 2013 Aug 6;18(8):9420-31. doi: 10.3390/molecules18089420.


3β,6β-Diacet-oxy-5,9α-dihy-droxy-5α-cholest-7-en-11-one acetic acid 0.04-solvate.

Piccialli V, Oliviero G, Borbone N, Centore R, Tuzi A.

Acta Crystallogr Sect E Struct Rep Online. 2013 May 11;69(Pt 6):o879-80. doi: 10.1107/S1600536813012646. Print 2013 Jun 1.

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