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Items: 1 to 20 of 492

1.

Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment.

Montanari S, Mahmoud AM, Pruccoli L, Rabbito A, Naldi M, Petralla S, Moraleda I, Bartolini M, Monti B, Iriepa I, Belluti F, Gobbi S, Di Marzo V, Bisi A, Tarozzi A, Ligresti A, Rampa A.

Eur J Med Chem. 2019 May 31;178:243-258. doi: 10.1016/j.ejmech.2019.05.080. [Epub ahead of print]

PMID:
31185414
2.

Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice.

Zamberletti E, Gabaglio M, Piscitelli F, Brodie JS, Woolley-Roberts M, Barbiero I, Tramarin M, Binelli G, Landsberger N, Kilstrup-Nielsen C, Rubino T, Di Marzo V, Parolaro D.

J Psychopharmacol. 2019 May 14:269881119844184. doi: 10.1177/0269881119844184. [Epub ahead of print]

PMID:
31084246
3.

Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier.

Tunisi L, Forte N, Fernández-Rilo AC, Mavaro I, Capasso R, D'Angelo L, Milić N, Cristino L, Di Marzo V, Palomba L.

Front Endocrinol (Lausanne). 2019 Apr 10;10:219. doi: 10.3389/fendo.2019.00219. eCollection 2019.

4.

Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats.

Petrie GN, Wills KL, Piscitelli F, Smoum R, Limebeer CL, Rock EM, Humphrey AE, Sheppard-Perkins M, Lichtman AH, Mechoulam R, Di Marzo V, Parker LA.

Psychopharmacology (Berl). 2019 Apr 16. doi: 10.1007/s00213-019-05237-9. [Epub ahead of print]

PMID:
30993360
5.

Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain.

Guida F, Boccella S, Belardo C, Iannotta M, Piscitelli F, De Filippis F, Paino S, Ricciardi F, Siniscalco D, Marabese I, Luongo L, Ercolini D, Di Marzo V, Maione S.

Brain Behav Immun. 2019 Apr 3. pii: S0889-1591(18)31247-9. doi: 10.1016/j.bbi.2019.04.006. [Epub ahead of print]

6.

In Silico Identification and Experimental Validation of (-)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator.

D'Aniello E, Iannotti FA, Falkenberg LG, Martella A, Gentile A, De Maio F, Ciavatta ML, Gavagnin M, Waxman JS, Di Marzo V, Amodeo P, Vitale RM.

Mar Drugs. 2019 Feb 12;17(2). pii: E110. doi: 10.3390/md17020110.

7.

Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis.

Everard A, Plovier H, Rastelli M, Van Hul M, de Wouters d'Oplinter A, Geurts L, Druart C, Robine S, Delzenne NM, Muccioli GG, de Vos WM, Luquet S, Flamand N, Di Marzo V, Cani PD.

Nat Commun. 2019 Jan 28;10(1):457. doi: 10.1038/s41467-018-08051-7.

8.

Identification and characterization of phytocannabinoids as novel dual PPARα/γ agonists by a computational and in vitro experimental approach.

D'Aniello E, Fellous T, Iannotti FA, Gentile A, Allarà M, Balestrieri F, Gray R, Amodeo P, Vitale RM, Di Marzo V.

Biochim Biophys Acta Gen Subj. 2019 Mar;1863(3):586-597. doi: 10.1016/j.bbagen.2019.01.002. Epub 2019 Jan 3.

PMID:
30611848
9.

Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system.

Salaga M, Binienda A, Piscitelli F, Mokrowiecka A, Cygankiewicz AI, Verde R, Malecka-Panas E, Kordek R, Krajewska WM, Di Marzo V, Fichna J.

Biochem Pharmacol. 2019 Mar;161:37-51. doi: 10.1016/j.bcp.2019.01.001. Epub 2019 Jan 3.

PMID:
30611738
10.

Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season.

Forner-Piquer I, Mylonas CC, Fakriadis I, Papadaki M, Piscitelli F, Di Marzo V, Calduch-Giner J, Pérez-Sánchez J, Carnevali O.

Arch Toxicol. 2019 Mar;93(3):727-741. doi: 10.1007/s00204-018-2378-6. Epub 2019 Jan 2.

PMID:
30600365
11.

Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.

Stark T, Ruda-Kucerova J, Iannotti FA, D'Addario C, Di Marco R, Pekarik V, Drazanova E, Piscitelli F, Bari M, Babinska Z, Giurdanella G, Di Bartolomeo M, Salomone S, Sulcova A, Maccarrone M, Wotjak CT, Starcuk Z Jr, Drago F, Mechoulam R, Di Marzo V, Micale V.

Neuropharmacology. 2019 Mar 1;146:212-221. doi: 10.1016/j.neuropharm.2018.11.035. Epub 2018 Nov 26.

PMID:
30496751
12.

Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest.

Vitale RM, D'Aniello E, Gorbi S, Martella A, Silvestri C, Giuliani ME, Fellous T, Gentile A, Carbone M, Cutignano A, Grauso L, Magliozzi L, Polese G, D'Aniello B, Defranoux F, Felline S, Terlizzi A, Calignano A, Regoli F, Di Marzo V, Amodeo P, Mollo E.

Mar Drugs. 2018 Nov 3;16(11). pii: E431. doi: 10.3390/md16110431.

13.

Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease.

Mugnaini C, Rabbito A, Brizzi A, Palombi N, Petrosino S, Verde R, Di Marzo V, Ligresti A, Corelli F.

Eur J Med Chem. 2019 Jan 1;161:239-251. doi: 10.1016/j.ejmech.2018.09.070. Epub 2018 Oct 13.

PMID:
30359820
14.

Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway.

Boccella S, Cristiano C, Romano R, Iannotta M, Belardo C, Farina A, Guida F, Piscitelli F, Palazzo E, Mazzitelli M, Imperatore R, Tunisi L, de Novellis V, Cristino L, Di Marzo V, Calignano A, Maione S, Luongo L.

Neurobiol Dis. 2019 Jan;121:106-119. doi: 10.1016/j.nbd.2018.09.023. Epub 2018 Sep 25.

PMID:
30266286
15.

Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy.

Iannotti FA, Pagano E, Guardiola O, Adinolfi S, Saccone V, Consalvi S, Piscitelli F, Gazzerro E, Busetto G, Carrella D, Capasso R, Puri PL, Minchiotti G, Di Marzo V.

Nat Commun. 2018 Sep 27;9(1):3950. doi: 10.1038/s41467-018-06267-1.

16.

FAAH-Catalyzed C-C Bond Cleavage of a New Multitarget Analgesic Drug.

Ligresti A, Silvestri C, Vitale RM, Martos JL, Piscitelli F, Wang JW, Allarà M, Carling RW, Luongo L, Guida F, Illiano A, Amoresano A, Maione S, Amodeo P, Woodward DF, Di Marzo V, Marino G.

ACS Chem Neurosci. 2019 Jan 16;10(1):424-437. doi: 10.1021/acschemneuro.8b00315. Epub 2018 Oct 4.

PMID:
30226747
17.

Author Correction: CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes.

Hegyi Z, Oláh T, Kőszeghy Á, Piscitelli F, Holló K, Pál B, Csernoch L, Marzo VD, Antal M.

Sci Rep. 2018 Sep 7;8(1):13715. doi: 10.1038/s41598-018-30573-9.

18.

Elongation of the Hydrophobic Chain as a Molecular Switch: Discovery of Capsaicin Derivatives and Endogenous Lipids as Potent Transient Receptor Potential Vanilloid Channel 2 Antagonists.

Schiano Moriello A, López Chinarro S, Novo Fernández O, Eras J, Amodeo P, Canela-Garayoa R, Vitale RM, Di Marzo V, De Petrocellis L.

J Med Chem. 2018 Sep 27;61(18):8255-8281. doi: 10.1021/acs.jmedchem.8b00734. Epub 2018 Sep 14.

PMID:
30176215
19.

Δ9-tetrahydrocannabivarin impairs epithelial calcium transport through inhibition of TRPV5 and TRPV6.

Janssens A, Silvestri C, Martella A, Vanoevelen JM, Di Marzo V, Voets T.

Pharmacol Res. 2018 Oct;136:83-89. doi: 10.1016/j.phrs.2018.08.021. Epub 2018 Aug 28.

PMID:
30170189
20.

Corrigendum: New approaches and challenges to targeting the endocannabinoid system.

Marzo VD.

Nat Rev Drug Discov. 2018 Aug 30;17(9):688. doi: 10.1038/nrd.2018.155.

PMID:
30160249

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