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Items: 1 to 20 of 79

1.

Empagliflozin reduces high glucose-induced oxidative stress and miR-21-dependent TRAF3IP2 induction and RECK suppression, and inhibits human renal proximal tubular epithelial cell migration and epithelial-to-mesenchymal transition.

Das NA, Carpenter AJ, Belenchia A, Aroor AR, Noda M, Siebenlist U, Chandrasekar B, DeMarco VG.

Cell Signal. 2019 Dec 17;68:109506. doi: 10.1016/j.cellsig.2019.109506. [Epub ahead of print]

PMID:
31862399
2.

The combination of a neprilysin inhibitor (sacubitril) and angiotensin-II receptor blocker (valsartan) attenuates glomerular and tubular injury in the Zucker Obese rat.

Habibi J, Aroor AR, Das NA, Manrique-Acevedo CM, Johnson MS, Hayden MR, Nistala R, Wiedmeyer C, Chandrasekar B, DeMarco VG.

Cardiovasc Diabetol. 2019 Mar 25;18(1):40. doi: 10.1186/s12933-019-0847-8.

3.

Empagliflozin Ameliorates Type 2 Diabetes-Induced Ultrastructural Remodeling of the Neurovascular Unit and Neuroglia in the Female db/db Mouse.

Hayden MR, Grant DG, Aroor AR, DeMarco VG.

Brain Sci. 2019 Mar 7;9(3). pii: E57. doi: 10.3390/brainsci9030057.

4.

Comparison of Cardiac miRNA Transcriptomes Induced by Diabetes and Rapamycin Treatment and Identification of a Rapamycin-Associated Cardiac MicroRNA Signature.

Belenchia AM, Gavini MP, Toedebusch RG, DeMarco VG, Pulakat L.

Oxid Med Cell Longev. 2018 Dec 17;2018:8364608. doi: 10.1155/2018/8364608. eCollection 2018.

5.

Glycemic control by the SGLT2 inhibitor empagliflozin decreases aortic stiffness, renal resistivity index and kidney injury.

Aroor AR, Das NA, Carpenter AJ, Habibi J, Jia G, Ramirez-Perez FI, Martinez-Lemus L, Manrique-Acevedo CM, Hayden MR, Duta C, Nistala R, Mayoux E, Padilla J, Chandrasekar B, DeMarco VG.

Cardiovasc Diabetol. 2018 Jul 30;17(1):108. doi: 10.1186/s12933-018-0750-8.

6.

The role of dipeptidylpeptidase-4 inhibitors in management of cardiovascular disease in diabetes; focus on linagliptin.

Aroor AR, Manrique-Acevedo C, DeMarco VG.

Cardiovasc Diabetol. 2018 Apr 18;17(1):59. doi: 10.1186/s12933-018-0704-1. Review.

7.

Cardiovascular disease progression in female Zucker Diabetic Fatty rats occurs via unique mechanisms compared to males.

Lum-Naihe K, Toedebusch R, Mahmood A, Bajwa J, Carmack T, Kumar SA, Ardhanari S, DeMarco VG, Emter CA, Pulakat L.

Sci Rep. 2017 Dec 19;7(1):17823. doi: 10.1038/s41598-017-18003-8.

8.

Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II-Induced Cardiac Diastolic Dysfunction in Male Mice.

Brown SM, Smith CE, Meuth AI, Khan M, Aroor AR, Cleeton HM, Meininger GA, Sowers JR, DeMarco VG, Chandrasekar B, Nistala R, Bender SB.

Endocrinology. 2017 Oct 1;158(10):3592-3604. doi: 10.1210/en.2017-00416.

9.

TRAF3IP2 mediates high glucose-induced endothelin-1 production as well as endothelin-1-induced inflammation in endothelial cells.

Padilla J, Carpenter AJ, Das NA, Kandikattu HK, López-Ongil S, Martinez-Lemus LA, Siebenlist U, DeMarco VG, Chandrasekar B.

Am J Physiol Heart Circ Physiol. 2018 Jan 1;314(1):H52-H64. doi: 10.1152/ajpheart.00478.2017. Epub 2017 Sep 29.

10.

Enhanced endothelium epithelial sodium channel signaling prompts left ventricular diastolic dysfunction in obese female mice.

Jia G, Habibi J, Aroor AR, Hill MA, DeMarco VG, Lee LE, Ma L, Barron BJ, Whaley-Connell A, Sowers JR.

Metabolism. 2018 Jan;78:69-79. doi: 10.1016/j.metabol.2017.08.008. Epub 2017 Sep 8.

PMID:
28920862
11.

Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice.

Aroor AR, Jia G, Habibi J, Sun Z, Ramirez-Perez FI, Brady B, Chen D, Martinez-Lemus LA, Manrique C, Nistala R, Whaley-Connell AT, Demarco VG, Meininger GA, Sowers JR.

Metabolism. 2017 Sep;74:32-40. doi: 10.1016/j.metabol.2017.06.006. Epub 2017 Jun 21.

12.

Amiloride Improves Endothelial Function and Reduces Vascular Stiffness in Female Mice Fed a Western Diet.

Martinez-Lemus LA, Aroor AR, Ramirez-Perez FI, Jia G, Habibi J, DeMarco VG, Barron B, Whaley-Connell A, Nistala R, Sowers JR.

Front Physiol. 2017 Jun 30;8:456. doi: 10.3389/fphys.2017.00456. eCollection 2017.

13.

Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice.

Aroor AR, Habibi J, Kandikattu HK, Garro-Kacher M, Barron B, Chen D, Hayden MR, Whaley-Connell A, Bender SB, Klein T, Padilla J, Sowers JR, Chandrasekar B, DeMarco VG.

Cardiovasc Diabetol. 2017 May 5;16(1):61. doi: 10.1186/s12933-017-0544-4.

14.

Differential Regulation of Cardiac Function and Intracardiac Cytokines by Rapamycin in Healthy and Diabetic Rats.

Luck C, DeMarco VG, Mahmood A, Gavini MP, Pulakat L.

Oxid Med Cell Longev. 2017;2017:5724046. doi: 10.1155/2017/5724046. Epub 2017 Mar 20.

15.

Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes.

Habibi J, Aroor AR, Sowers JR, Jia G, Hayden MR, Garro M, Barron B, Mayoux E, Rector RS, Whaley-Connell A, DeMarco VG.

Cardiovasc Diabetol. 2017 Jan 13;16(1):9. doi: 10.1186/s12933-016-0489-z.

16.

Targeting TRAF3IP2 by Genetic and Interventional Approaches Inhibits Ischemia/Reperfusion-induced Myocardial Injury and Adverse Remodeling.

Erikson JM, Valente AJ, Mummidi S, Kandikattu HK, DeMarco VG, Bender SB, Fay WP, Siebenlist U, Chandrasekar B.

J Biol Chem. 2017 Feb 10;292(6):2345-2358. doi: 10.1074/jbc.M116.764522. Epub 2017 Jan 4.

17.

Daily exercise prevents diastolic dysfunction and oxidative stress in a female mouse model of western diet induced obesity by maintaining cardiac heme oxygenase-1 levels.

Bostick B, Aroor AR, Habibi J, Durante W, Ma L, DeMarco VG, Garro M, Hayden MR, Booth FW, Sowers JR.

Metabolism. 2017 Jan;66:14-22. doi: 10.1016/j.metabol.2016.09.005. Epub 2016 Sep 22.

18.

Regular Exercise Reduces Endothelial Cortical Stiffness in Western Diet-Fed Female Mice.

Padilla J, Ramirez-Perez FI, Habibi J, Bostick B, Aroor AR, Hayden MR, Jia G, Garro M, DeMarco VG, Manrique C, Booth FW, Martinez-Lemus LA, Sowers JR.

Hypertension. 2016 Nov;68(5):1236-1244. Epub 2016 Aug 29.

19.

Dipeptidyl peptidase-4 inhibition with linagliptin prevents western diet-induced vascular abnormalities in female mice.

Manrique C, Habibi J, Aroor AR, Sowers JR, Jia G, Hayden MR, Garro M, Martinez-Lemus LA, Ramirez-Perez FI, Klein T, Meininger GA, DeMarco VG.

Cardiovasc Diabetol. 2016 Jul 8;15:94. doi: 10.1186/s12933-016-0414-5.

20.

Endothelial Mineralocorticoid Receptor Mediates Diet-Induced Aortic Stiffness in Females.

Jia G, Habibi J, Aroor AR, Martinez-Lemus LA, DeMarco VG, Ramirez-Perez FI, Sun Z, Hayden MR, Meininger GA, Mueller KB, Jaffe IZ, Sowers JR.

Circ Res. 2016 Mar 18;118(6):935-943. doi: 10.1161/CIRCRESAHA.115.308269. Epub 2016 Feb 15.

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