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Items: 1 to 20 of 88

1.

A Role for MMP-10 (Matrix Metalloproteinase-10) in Calcific Aortic Valve Stenosis.

Matilla L, Roncal C, Ibarrola J, Arrieta V, García-Peña A, Fernández-Celis A, Navarro A, Álvarez V, Gainza A, Orbe J, Cachofeiro V, Zalba G, Sádaba R, Rodríguez JA, López-Andrés N.

Arterioscler Thromb Vasc Biol. 2020 Mar 19:ATVBAHA120314143. doi: 10.1161/ATVBAHA.120.314143. [Epub ahead of print]

PMID:
32188274
2.

The Crosstalk between Cardiac Lipotoxicity and Mitochondrial Oxidative Stress in the Cardiac Alterations in Diet-Induced Obesity in Rats.

Jiménez-González S, Marín-Royo G, Jurado-López R, Bartolomé MV, Romero-Miranda A, Luaces M, Islas F, Nieto ML, Martínez-Martínez E, Cachofeiro V.

Cells. 2020 Feb 17;9(2). pii: E451. doi: 10.3390/cells9020451.

3.

Secreted Phospholipase A2-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation-Fibrosis Link.

Martin R, Gutierrez B, Cordova C, Roman AS, Alvarez Y, Hernandez M, Cachofeiro V, Nieto ML.

Cells. 2020 Feb 8;9(2). pii: E396. doi: 10.3390/cells9020396.

4.

Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges.

Martínez-González J, Varona S, Cañes L, Galán M, Briones AM, Cachofeiro V, Rodríguez C.

Biomolecules. 2019 Oct 14;9(10). pii: E610. doi: 10.3390/biom9100610. Review.

5.

The role of mitochondrial oxidative stress in the metabolic alterations in diet-induced obesity in rats.

Marín-Royo G, Rodríguez C, Le Pape A, Jurado-López R, Luaces M, Antequera A, Martínez-González J, Souza-Neto FV, Nieto ML, Martínez-Martínez E, Cachofeiro V.

FASEB J. 2019 Nov;33(11):12060-12072. doi: 10.1096/fj.201900347RR. Epub 2019 Aug 1.

PMID:
31370681
6.

The Impact of Cardiac Lipotoxicity on Cardiac Function and Mirnas Signature in Obese and Non-Obese Rats with Myocardial Infarction.

Marín-Royo G, Ortega-Hernández A, Martínez-Martínez E, Jurado-López R, Luaces M, Islas F, Gómez-Garre D, Delgado-Valero B, Lagunas E, Ramchandani B, García-Bouza M, Nieto ML, Cachofeiro V.

Sci Rep. 2019 Jan 24;9(1):444. doi: 10.1038/s41598-018-36914-y.

7.

mPGES-1 (Microsomal Prostaglandin E Synthase-1) Mediates Vascular Dysfunction in Hypertension Through Oxidative Stress.

Avendaño MS, García-Redondo AB, Zalba G, González-Amor M, Aguado A, Martínez-Revelles S, Beltrán LM, Camacho M, Cachofeiro V, Alonso MJ, Salaices M, Briones AM.

Hypertension. 2018 Aug;72(2):492-502. doi: 10.1161/HYPERTENSIONAHA.118.10833. Epub 2018 Jun 11.

PMID:
29891646
8.

Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12.

Ibarrola J, Sadaba R, Martinez-Martinez E, Garcia-Peña A, Arrieta V, Alvarez V, Fernández-Celis A, Gainza A, Cachofeiro V, Santamaria E, Fernandez-Irigoyen J, Jaisser F, Lopez-Andres N.

Sci Rep. 2018 May 1;8(1):6801. doi: 10.1038/s41598-018-25068-6.

9.

Galectin-3 down-regulates antioxidant peroxiredoxin-4 in human cardiac fibroblasts: a new pathway to induce cardiac damage.

Ibarrola J, Arrieta V, Sádaba R, Martinez-Martinez E, Garcia-Peña A, Alvarez V, Fernández-Celis A, Gainza A, Santamaría E, Fernández-Irigoyen J, Cachofeiro V, Zalba G, Fay R, Rossignol P, López-Andrés N.

Clin Sci (Lond). 2018 Jul 18;132(13):1471-1485. doi: 10.1042/CS20171389. Print 2018 Jul 18.

PMID:
29674526
10.

A role for fumarate hydratase in mediating oxidative effects of galectin-3 in human cardiac fibroblasts.

Ibarrola J, Sádaba R, Garcia-Peña A, Arrieta V, Martinez-Martinez E, Alvarez V, Fernández-Celis A, Gainza A, Santamaría E, Fernández-Irigoyen J, Cachofeiro V, Fay R, Rossignol P, López-Andrés N.

Int J Cardiol. 2018 May 1;258:217-223. doi: 10.1016/j.ijcard.2017.12.103.

PMID:
29544935
11.

Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity.

Marín-Royo G, Gallardo I, Martínez-Martínez E, Gutiérrez B, Jurado-López R, López-Andrés N, Gutiérrez-Tenorio J, Rial E, Bartolomé MAV, Nieto ML, Cachofeiro V.

Dis Model Mech. 2018 Feb 5;11(2). pii: dmm032086. doi: 10.1242/dmm.032086.

12.

The role of oxidative stress in the crosstalk between leptin and mineralocorticoid receptor in the cardiac fibrosis associated with obesity.

Gutiérrez-Tenorio J, Marín-Royo G, Martínez-Martínez E, Martín R, Miana M, López-Andrés N, Jurado-López R, Gallardo I, Luaces M, San Román JA, González-Amor M, Salaices M, Nieto ML, Cachofeiro V.

Sci Rep. 2017 Dec 1;7(1):16802. doi: 10.1038/s41598-017-17103-9.

13.

The impact of obesity in the cardiac lipidome and its consequences in the cardiac damage observed in obese rats.

Marín-Royo G, Martínez-Martínez E, Gutiérrez B, Jurado-López R, Gallardo I, Montero O, Bartolomé MV, San Román JA, Salaices M, Nieto ML, Cachofeiro V.

Clin Investig Arterioscler. 2018 Jan - Feb;30(1):10-20. doi: 10.1016/j.arteri.2017.07.004. Epub 2017 Aug 30. English, Spanish.

14.

Galectin-3 pharmacological inhibition attenuates early renal damage in spontaneously hypertensive rats.

Martínez-Martínez E, Ibarrola J, Fernández-Celis A, Calvier L, Leroy C, Cachofeiro V, Rossignol P, López-Andrés N.

J Hypertens. 2018 Feb;36(2):368-376. doi: 10.1097/HJH.0000000000001545.

PMID:
28858976
15.

A role for galectin-3 in the development of early molecular alterations in short-term aortic stenosis.

Arrieta V, Martinez-Martinez E, Ibarrola J, Alvarez V, Sádaba R, Garcia-Peña A, Fernández-Celis A, Cachofeiro V, Rossignol P, López-Andrés N.

Clin Sci (Lond). 2017 May 1;131(10):935-949. doi: 10.1042/CS20170145. Epub 2017 Mar 30.

PMID:
28360193
16.

Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels.

Lucas E, Vila-Bedmar R, Arcones AC, Cruces-Sande M, Cachofeiro V, Mayor F Jr, Murga C.

Cardiovasc Diabetol. 2016 Nov 10;15(1):155.

17.

Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage.

Martinez-Martinez E, Ibarrola J, Calvier L, Fernandez-Celis A, Leroy C, Cachofeiro V, Rossignol P, Lopez-Andres N.

PLoS One. 2016 Nov 9;11(11):e0166272. doi: 10.1371/journal.pone.0166272. eCollection 2016.

18.

Role for Galectin-3 in Calcific Aortic Valve Stenosis.

Sádaba JR, Martínez-Martínez E, Arrieta V, Álvarez V, Fernández-Celis A, Ibarrola J, Melero A, Rossignol P, Cachofeiro V, López-Andrés N.

J Am Heart Assoc. 2016 Nov 4;5(11). pii: e004360.

19.

High levels of circulating TNFR1 increase the risk of all-cause mortality and progression of renal disease in type 2 diabetic nephropathy.

Fernández-Juárez G, Villacorta Perez J, Luño Fernández JL, Martinez-Martinez E, Cachofeiro V, Barrio Lucia V, Tato Ribera AM, Mendez Abreu A, Cordon A, Oliva Dominguez JA, Praga Terente M.

Nephrology (Carlton). 2017 May;22(5):354-360. doi: 10.1111/nep.12781.

PMID:
27003829
20.

The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats.

Martínez-Martínez E, Rodríguez C, Galán M, Miana M, Jurado-López R, Bartolomé MV, Luaces M, Islas F, Martínez-González J, López-Andrés N, Cachofeiro V.

J Mol Cell Cardiol. 2016 Mar;92:96-104. doi: 10.1016/j.yjmcc.2016.01.012. Epub 2016 Jan 15.

PMID:
26780438

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