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Items: 1 to 20 of 47


Gender-Specific Beneficial Effects of Docosahexaenoic Acid Dietary Supplementation in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice.

Torres P, Cacabelos D, Pairada J, Bauer KC, Boada J, Fontdevila L, Rossi C, Povedano M, Ferrer I, Pamplona R, Finlay BB, Portero-Otín M, Ayala V.

Neurotherapeutics. 2019 Nov 21. doi: 10.1007/s13311-019-00808-2. [Epub ahead of print]


Effects of Aging and Methionine Restriction on Rat Kidney Metabolome.

Pradas I, Jové M, Cabré R, Ayala V, Mota-Martorell N, Pamplona R.

Metabolites. 2019 Nov 14;9(11). pii: E280. doi: 10.3390/metabo9110280.


[Epirubicina neoadyuvante con o sin docetaxel secuencial en el tratamiento del cáncer de mama avanzado: evaluación de la respuesta patológica completa y tolerabilidad de la quimioterapia].

Ramírez-Torres N, Pérez-Puentes A, Moctezuma-Meza C, Victoria-Ayala R, Ortiz-Rodríguez K, Valenzuela-Martínez LA, Ayala-Anzures ME.

Cir Cir. 2019;87(1):59-68. doi: 10.24875/CIRU.18000425. Spanish.


Lipidomics Reveals a Tissue-Specific Fingerprint.

Pradas I, Huynh K, Cabré R, Ayala V, Meikle PJ, Jové M, Pamplona R.

Front Physiol. 2018 Aug 28;9:1165. doi: 10.3389/fphys.2018.01165. eCollection 2018.


Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue.

Torres P, Ramírez-Núñez O, Romero-Guevara R, Barés G, Granado-Serrano AB, Ayala V, Boada J, Fontdevila L, Povedano M, Sanchís D, Pamplona R, Ferrer I, Portero-Otín M.

Autophagy. 2018;14(8):1398-1403. doi: 10.1080/15548627.2018.1474311. Epub 2018 Jul 28.


Lipid Profile in Human Frontal Cortex Is Sustained Throughout Healthy Adult Life Span to Decay at Advanced Ages.

Cabré R, Naudí A, Dominguez-Gonzalez M, Jové M, Ayala V, Mota-Martorell N, Pradas I, Nogueras L, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):703-710. doi: 10.1093/gerona/glx164.


Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system.

Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):485-495. doi: 10.1016/j.bbalip.2017.02.001. Epub 2017 Feb 7.


Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex.

Cabré R, Jové M, Naudí A, Ayala V, Piñol-Ripoll G, Gil-Villar MP, Dominguez-Gonzalez M, Obis È, Berdun R, Mota-Martorell N, Portero-Otin M, Ferrer I, Pamplona R.

Front Mol Neurosci. 2016 Dec 8;9:138. doi: 10.3389/fnmol.2016.00138. eCollection 2016.


Sixty years old is the breakpoint of human frontal cortex aging.

Cabré R, Naudí A, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

Free Radic Biol Med. 2017 Feb;103:14-22. doi: 10.1016/j.freeradbiomed.2016.12.010. Epub 2016 Dec 13.


Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis.

Cacabelos D, Ayala V, Granado-Serrano AB, Jové M, Torres P, Boada J, Cabré R, Ramírez-Núñez O, Gonzalo H, Soler-Cantero A, Serrano JC, Bellmunt MJ, Romero MP, Motilva MJ, Nonaka T, Hasegawa M, Ferrer I, Pamplona R, Portero-Otín M.

Neurobiol Dis. 2016 Apr;88:148-60. doi: 10.1016/j.nbd.2016.01.007. Epub 2016 Jan 12.


Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS.

Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J.

Acta Neuropathol Commun. 2016 Jan 13;4:3. doi: 10.1186/s40478-015-0271-6.


Lipidomics of human brain aging and Alzheimer's disease pathology.

Naudí A, Cabré R, Jové M, Ayala V, Gonzalo H, Portero-Otín M, Ferrer I, Pamplona R.

Int Rev Neurobiol. 2015;122:133-89. doi: 10.1016/bs.irn.2015.05.008. Epub 2015 Jun 19. Review.


Target of rapamycin activation predicts lifespan in fruit flies.

Scialò F, Sriram A, Naudí A, Ayala V, Jové M, Pamplona R, Sanz A.

Cell Cycle. 2015;14(18):2949-58. doi: 10.1080/15384101.2015.1071745.


Do primary health centres and hospitals contribute equally towards achievement of the transversal clinical competencies of medical students? Performance on the Objective Structured Clinical Examination (OSCE) in competency acquisition.

Soler-González J, Buti M, Boada J, Ayala V, Peñascal E, Rodriguez T; GERDS group.

Aten Primaria. 2016 Jan;48(1):42-8. doi: 10.1016/j.aprim.2015.02.005. Epub 2015 Apr 19.


Dietary lipid unsaturation influences survival and oxidative modifications of an amyotrophic lateral sclerosis model in a gender-specific manner.

Cacabelos D, Ayala V, Ramírez-Nunez O, Granado-Serrano AB, Boada J, Serrano JC, Cabré R, Nadal-Rey G, Bellmunt MJ, Ferrer I, Pamplona R, Portero-Otin M.

Neuromolecular Med. 2014 Dec;16(4):669-85. doi: 10.1007/s12017-014-8317-7. Epub 2014 Jul 1.


Membrane lipid unsaturation as physiological adaptation to animal longevity.

Naudí A, Jové M, Ayala V, Portero-Otín M, Barja G, Pamplona R.

Front Physiol. 2013 Dec 17;4:372. doi: 10.3389/fphys.2013.00372. Review.


Plasma long-chain free fatty acids predict mammalian longevity.

Jové M, Naudí A, Aledo JC, Cabré R, Ayala V, Portero-Otin M, Barja G, Pamplona R.

Sci Rep. 2013 Nov 28;3:3346. doi: 10.1038/srep03346.


[A study of selective neuronal vulnerability in the human central nervous system].

Naudí A, Jové M, Ayala V, Cabré R, Portero-Otin M, Ferrer I, Pamplona R.

Rev Esp Geriatr Gerontol. 2013 Sep-Oct;48(5):216-23. doi: 10.1016/j.regg.2013.04.005. Epub 2013 Sep 5. Spanish.


Specific lipidome signatures in central nervous system from methionine-restricted mice.

Jové M, Ayala V, Ramírez-Núñez O, Naudí A, Cabré R, Spickett CM, Portero-Otín M, Pamplona R.

J Proteome Res. 2013 Jun 7;12(6):2679-89. doi: 10.1021/pr400064a. Epub 2013 Apr 30.


Non-enzymatic modification of aminophospholipids by carbonyl-amine reactions.

Naudí A, Jové M, Ayala V, Cabré R, Portero-Otín M, Pamplona R.

Int J Mol Sci. 2013 Feb 5;14(2):3285-313. doi: 10.3390/ijms14023285.

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