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Items: 1 to 20 of 27


12-HETE is a regulator of PGE2 production via COX-2 expression induced by a snake venom group IIA phospholipase A2 in isolated peritoneal macrophages.

Moreira V, Gutiérrez JM, Lomonte B, Ramirez Vinolo MA, Curi R, Lambeau G, Teixeira C.

Chem Biol Interact. 2019 Dec 4:108903. doi: 10.1016/j.cbi.2019.108903. [Epub ahead of print]


Vitamin A supplementation according to zinc status on oxidative stress levels in cardiac surgery patients.

Matos A, Souza G, Moreira V, Luna M, Ramalho A.

Nutr Hosp. 2018 Jun 22;35(4):767-773. doi: 10.20960/nh.1666.


Genistein and Ascorbic Acid Reduce Oxidative Stress-Derived DNA Damage Induced by the Antileishmanial Meglumine Antimoniate.

de Jesus LCL, Soares RP, Moreira VR, Pontes RL, Castelo-Branco PV, Pereira SRF.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00456-18. doi: 10.1128/AAC.00456-18. Print 2018 Sep.


Orange juice affects acylcarnitine metabolism in healthy volunteers as revealed by a mass-spectrometry based metabolomics approach.

Moreira V, Brasili E, Fiamoncini J, Marini F, Miccheli A, Daniel H, Lee JJH, Hassimotto NMA, Lajolo FM.

Food Res Int. 2018 May;107:346-352. doi: 10.1016/j.foodres.2018.02.046. Epub 2018 Feb 21.


A snake venom group IIA PLA2 with immunomodulatory activity induces formation of lipid droplets containing 15-d-PGJ2 in macrophages.

Giannotti KC, Leiguez E, Carvalho AEZ, Nascimento NG, Matsubara MH, Fortes-Dias CL, Moreira V, Teixeira C.

Sci Rep. 2017 Jun 22;7(1):4098. doi: 10.1038/s41598-017-04498-8.


Meglumine Antimoniate (Glucantime) Causes Oxidative Stress-Derived DNA Damage in BALB/c Mice Infected by Leishmania (Leishmania) infantum.

Moreira VR, de Jesus LCL, Soares RP, Silva LDM, Pinto BAS, Melo MN, Paes AMA, Pereira SRF.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02360-16. doi: 10.1128/AAC.02360-16. Print 2017 Jun.


The antileishmanial drug miltefosine (Impavido(®)) causes oxidation of DNA bases, apoptosis, and necrosis in mammalian cells.

Castelo Branco PV, Soares RE, de Jesus LC, Moreira VR, Alves HJ, de Castro Belfort MR, Silva VL, Ferreira Pereira SR.

Mutat Res Genet Toxicol Environ Mutagen. 2016 Aug;806:34-9. doi: 10.1016/j.mrgentox.2016.06.007. Epub 2016 Jun 24.


The role of TLR2 in the acute inflammatory response induced by Bothrops atrox snake venom.

Moreira V, Teixeira C, Borges da Silva H, D'Império Lima MR, Dos-Santos MC.

Toxicon. 2016 Aug;118:121-8. doi: 10.1016/j.toxicon.2016.04.042. Epub 2016 Apr 21.


An Asp49 phospholipase A2 from snake venom induces cyclooxygenase-2 expression and prostaglandin E2 production via activation of NF-κB, p38MAPK, and PKC in macrophages.

Moreira V, Lomonte B, Vinolo MA, Curi R, Gutiérrez JM, Teixeira C.

Mediators Inflamm. 2014;2014:105879. doi: 10.1155/2014/105879. Epub 2014 Apr 6.


Critical role of TLR2 and MyD88 for functional response of macrophages to a group IIA-secreted phospholipase A2 from snake venom.

Leiguez E, Giannotti KC, Moreira V, Matsubara MH, Gutiérrez JM, Lomonte B, Rodríguez JP, Balsinde J, Teixeira C.

PLoS One. 2014 Apr 9;9(4):e93741. doi: 10.1371/journal.pone.0093741. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e105241.


A Lys49 phospholipase A2, isolated from Bothrops asper snake venom, induces lipid droplet formation in macrophages which depends on distinct signaling pathways and the C-terminal region.

Giannotti KC, Leiguez E, Moreira V, Nascimento NG, Lomonte B, Gutiérrez JM, Lopes de Melo R, Teixeira C.

Biomed Res Int. 2013;2013:807982. doi: 10.1155/2013/807982. Epub 2012 Dec 24.


Inhibition of carrageenan-induced acute inflammation in mice by oral administration of anthocyanin mixture from wild mulberry and cyanidin-3-glucoside.

Hassimotto NM, Moreira V, do Nascimento NG, Souto PC, Teixeira C, Lajolo FM.

Biomed Res Int. 2013;2013:146716. doi: 10.1155/2013/146716. Epub 2013 Jan 17.


The crucial role of the MyD88 adaptor protein in the inflammatory response induced by Bothrops atrox venom.

Moreira V, Teixeira C, Borges da Silva H, D'Império Lima MR, Dos-Santos MC.

Toxicon. 2013 Jun 1;67:37-46. doi: 10.1016/j.toxicon.2013.02.010. Epub 2013 Mar 5.


A catalytically-inactive snake venom Lys49 phospholipase A₂ homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages.

Moreira V, de Castro Souto PC, Ramirez Vinolo MA, Lomonte B, María Gutiérrez J, Curi R, Teixeira C.

Eur J Pharmacol. 2013 May 15;708(1-3):68-79. doi: 10.1016/j.ejphar.2013.01.061. Epub 2013 Feb 14.


Pharmacological evaluation and preliminary pharmacokinetics studies of a new diclofenac prodrug without gastric ulceration effect.

Santos JL, Moreira V, Campos ML, Chelucci RC, Barbieri KP, de Castro Souto PC, Matsubara MH, Teixeira C, Bosquesi PL, Peccinini RG, Chin CM.

Int J Mol Sci. 2012 Nov 19;13(11):15305-20. doi: 10.3390/ijms131115305.


Local inflammatory events induced by Bothrops atrox snake venom and the release of distinct classes of inflammatory mediators.

Moreira V, Dos-Santos MC, Nascimento NG, Borges da Silva H, Fernandes CM, D'Império Lima MR, Teixeira C.

Toxicon. 2012 Jul;60(1):12-20. doi: 10.1016/j.toxicon.2012.03.004. Epub 2012 Mar 20.


A phospholipase A₂ from Bothrops asper snake venom activates neutrophils in culture: expression of cyclooxygenase-2 and PGE₂ biosynthesis.

Moreira V, Gutiérrez JM, Amaral RB, Lomonte B, Purgatto E, Teixeira C.

Toxicon. 2011 Feb;57(2):288-96. doi: 10.1016/j.toxicon.2010.12.004. Epub 2010 Dec 10.


Usefulness of cell-free plasma DNA, procalcitonin and C-reactive protein as markers of infection in febrile patients.

Moreira VG, Prieto B, Rodríguez JS, Alvarez FV.

Ann Clin Biochem. 2010 May;47(Pt 3):253-8. doi: 10.1258/acb.2010.009173. Epub 2010 Apr 26.


Growth hormone attenuates skeletal muscle changes in experimental chronic heart failure.

Santos DP, Okoshi K, Moreira VO, Seiva FR, Almeida FL, Padovani CR, Carvalho RF, Okoshi MP, Cicogna AC, Castro AV, Pai-Silva MD.

Growth Horm IGF Res. 2010 Apr;20(2):149-55. doi: 10.1016/j.ghir.2009.11.007. Epub 2010 Jan 8.


Inflammation induced by Bothrops asper venom.

Teixeira C, Cury Y, Moreira V, Picolob G, Chaves F.

Toxicon. 2009 Dec 1;54(7):988-97. Review.


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