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Items: 1 to 20 of 55


African KhoeSan ancestry linked to high-risk prostate cancer.

Petersen DC, Jaratlerdsiri W, van Wyk A, Chan EKF, Fernandez P, Lyons RJ, Mutambirw SBA, van der Merwe A, Venter PA, Bates W, Bornman MSR, Hayes VM.

BMC Med Genomics. 2019 Jun 4;12(1):82. doi: 10.1186/s12920-019-0537-0.


TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: A focus on Africa.

Blackburn J, Vecchiarelli S, Heyer EE, Patrick SM, Lyons RJ, Jaratlerdsiri W, van Zyl S, Bornman MSR, Mercer TR, Hayes VM.

Prostate. 2019 Jul;79(10):1191-1196. doi: 10.1002/pros.23823. Epub 2019 May 15.


Diagnosis of fusion genes using targeted RNA sequencing.

Heyer EE, Deveson IW, Wooi D, Selinger CI, Lyons RJ, Hayes VM, O'Toole SA, Ballinger ML, Gill D, Thomas DM, Mercer TR, Blackburn J.

Nat Commun. 2019 Mar 27;10(1):1388. doi: 10.1038/s41467-019-09374-9.


Metagenomic and metatranscriptomic analysis of human prostate microbiota from patients with prostate cancer.

Feng Y, Ramnarine VR, Bell R, Volik S, Davicioni E, Hayes VM, Ren S, Collins CC.

BMC Genomics. 2019 Feb 18;20(1):146. doi: 10.1186/s12864-019-5457-z.


Prostate cancer genomics and racial health disparity.

Hayes VM, Jaratlerdsiri W, Bornman MSR.

Oncotarget. 2018 Nov 30;9(94):36650-36651. doi: 10.18632/oncotarget.26399. eCollection 2018 Nov 30. No abstract available.


Prostate Cancer in Southern Africa: Does Africa Hold Untapped Potential to Add Value to the Current Understanding of a Common Disease?

Hayes VM, Bornman MSR.

J Glob Oncol. 2018 Sep;4:1-7. doi: 10.1200/JGO.2016.008862. Epub 2017 Mar 21. No abstract available.


Whole-Genome Sequencing Reveals Elevated Tumor Mutational Burden and Initiating Driver Mutations in African Men with Treatment-Naïve, High-Risk Prostate Cancer.

Jaratlerdsiri W, Chan EKF, Gong T, Petersen DC, Kalsbeek AMF, Venter PA, Stricker PD, Bornman MSR, Hayes VM.

Cancer Res. 2018 Dec 15;78(24):6736-6746. doi: 10.1158/0008-5472.CAN-18-0254. Epub 2018 Sep 14.


Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten.

Nair SS, Luu PL, Qu W, Maddugoda M, Huschtscha L, Reddel R, Chenevix-Trench G, Toso M, Kench JG, Horvath LG, Hayes VM, Stricker PD, Hughes TP, White DL, Rasko JEJ, Wong JJ, Clark SJ.

Epigenetics Chromatin. 2018 May 28;11(1):24. doi: 10.1186/s13072-018-0194-0.


Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer.

Chan EKF, Cameron DL, Petersen DC, Lyons RJ, Baldi BF, Papenfuss AT, Thomas DM, Hayes VM.

Genome Res. 2018 May;28(5):726-738. doi: 10.1101/gr.227975.117. Epub 2018 Apr 4.


Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer.

Kalsbeek AMF, Chan EKF, Grogan J, Petersen DC, Jaratlerdsiri W, Gupta R, Lyons RJ, Haynes AM, Horvath LG, Kench JG, Stricker PD, Hayes VM.

Prostate. 2018 Jan;78(1):25-31. doi: 10.1002/pros.23440. Epub 2017 Nov 14.


Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management.

Kalsbeek AMF, Chan EKF, Corcoran NM, Hovens CM, Hayes VM.

Oncotarget. 2017 Aug 4;8(41):71342-71357. doi: 10.18632/oncotarget.19926. eCollection 2017 Sep 19. Review.


Reconstructing Prehistoric African Population Structure.

Skoglund P, Thompson JC, Prendergast ME, Mittnik A, Sirak K, Hajdinjak M, Salie T, Rohland N, Mallick S, Peltzer A, Heinze A, Olalde I, Ferry M, Harney E, Michel M, Stewardson K, Cerezo-Román JI, Chiumia C, Crowther A, Gomani-Chindebvu E, Gidna AO, Grillo KM, Helenius IT, Hellenthal G, Helm R, Horton M, López S, Mabulla AZP, Parkington J, Shipton C, Thomas MG, Tibesasa R, Welling M, Hayes VM, Kennett DJ, Ramesar R, Meyer M, Pääbo S, Patterson N, Morris AG, Boivin N, Pinhasi R, Krause J, Reich D.

Cell. 2017 Sep 21;171(1):59-71.e21. doi: 10.1016/j.cell.2017.08.049.


Next generation mapping reveals novel large genomic rearrangements in prostate cancer.

Jaratlerdsiri W, Chan EKF, Petersen DC, Yang C, Croucher PI, Bornman MSR, Sheth P, Hayes VM.

Oncotarget. 2017 Apr 4;8(14):23588-23602. doi: 10.18632/oncotarget.15802.


Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer.

Kalsbeek AM, Chan EF, Grogan J, Petersen DC, Jaratlerdsiri W, Gupta R, Lyons RJ, Haynes AM, Horvath LG, Kench JG, Stricker PD, Hayes VM.

Aging (Albany NY). 2016 Oct 5;8(11):2702-2712. doi: 10.18632/aging.101044.


Spectrum of mitochondrial genomic variation and associated clinical presentation of prostate cancer in South African men.

McCrow JP, Petersen DC, Louw M, Chan EK, Harmeyer K, Vecchiarelli S, Lyons RJ, Bornman MS, Hayes VM.

Prostate. 2016 Mar;76(4):349-58. doi: 10.1002/pros.23126. Epub 2015 Dec 10.


Target Acquired: Progress and Promise of Targeted Therapeutics in the Treatment of Prostate Cancer.

Stuchbery R, Kurganovs NJ, McCoy PJ, Nelson CC, Hayes VM, Corcoran NM, Hovens CM.

Curr Cancer Drug Targets. 2015;15(5):394-405. Review.


Revised timeline and distribution of the earliest diverged human maternal lineages in southern Africa.

Chan EK, Hardie RA, Petersen DC, Beeson K, Bornman RM, Smith AB, Hayes VM.

PLoS One. 2015 Mar 25;10(3):e0121223. doi: 10.1371/journal.pone.0121223. eCollection 2015.


First ancient mitochondrial human genome from a prepastoralist southern African.

Morris AG, Heinze A, Chan EK, Smith AB, Hayes VM.

Genome Biol Evol. 2014 Sep 10;6(10):2647-53. doi: 10.1093/gbe/evu202.


Clinical presentation of prostate cancer in black South Africans.

Tindall EA, Monare LR, Petersen DC, van Zyl S, Hardie RA, Segone AM, Venter PA, Bornman MS, Hayes VM.

Prostate. 2014 Jun;74(8):880-91. doi: 10.1002/pros.22806. Epub 2014 Apr 9.


Addressing the contribution of previously described genetic and epidemiological risk factors associated with increased prostate cancer risk and aggressive disease within men from South Africa.

Tindall EA, Bornman MS, van Zyl S, Segone AM, Monare LR, Venter PA, Hayes VM.

BMC Urol. 2013 Dec 29;13:74. doi: 10.1186/1471-2490-13-74.

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