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Items: 1 to 20 of 46


The GLP1R Agonist Liraglutide Reduces Hyperglucagonemia Induced by the SGLT2 Inhibitor Dapagliflozin via Somatostatin Release.

Saponaro C, Gmyr V, Thévenet J, Moerman E, Delalleau N, Pasquetti G, Coddeville A, Quenon A, Daoudi M, Hubert T, Vantyghem MC, Bousquet C, Martineau Y, Kerr-Conte J, Staels B, Pattou F, Bonner C.

Cell Rep. 2019 Aug 6;28(6):1447-1454.e4. doi: 10.1016/j.celrep.2019.07.009.


Islets for Research: Nothing Is Perfect, but We Can Do Better.

Nano R, Kerr-Conte JA, Bosco D, Karlsson M, Lavallard V, Melzi R, Gmyr V, Mercalli A, Berney T, Pattou F, Korsgren O, Piemonti L.

Diabetes. 2019 Aug;68(8):1541-1543. doi: 10.2337/db19-0367.


Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells.

Bertin A, Sane F, Gmyr V, Lobert D, Dechaumes A, Kerr-Conte J, Pattou F, Hober D.

Viruses. 2019 Jul 2;11(7). pii: E597. doi: 10.3390/v11070597.


Single Low Dose of Human Recombinant Antithrombin (Atryn®) Has no Impact on Endotoxin-induced Disseminated Intravascular Coagulation: An Experimental Randomized Open Label Controlled Study.

Duburcq T, Durand A, Tournoys A, Gnemmi V, Bonner C, Gmyr V, Hubert T, Pattou F, Jourdain M.

Shock. 2018 Oct 15. doi: 10.1097/SHK.0000000000001274. [Epub ahead of print]


Safety of Islet Autotransplantation After Pancreatectomy for Adenocarcinoma.

Renaud F, Chetboun M, Thevenet J, Delalleau N, Gmyr V, Hubert T, Bonner C, Messager M, Leteurtre E, Mariette C, Kerr-Conte J, Piessen G, Pattou F.

Transplantation. 2019 Jan;103(1):177-181. doi: 10.1097/TP.0000000000002419.


Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial.

Lablanche S, Vantyghem MC, Kessler L, Wojtusciszyn A, Borot S, Thivolet C, Girerd S, Bosco D, Bosson JL, Colin C, Tetaz R, Logerot S, Kerr-Conte J, Renard E, Penfornis A, Morelon E, Buron F, Skaare K, Grguric G, Camillo-Brault C, Egelhofer H, Benomar K, Badet L, Berney T, Pattou F, Benhamou PY; TRIMECO trial investigators.

Lancet Diabetes Endocrinol. 2018 Jul;6(7):527-537. doi: 10.1016/S2213-8587(18)30078-0. Epub 2018 May 15.


Sodium lactate improves renal microvascular thrombosis compared to sodium bicarbonate and 0.9% NaCl in a porcine model of endotoxic shock: an experimental randomized open label controlled study.

Duburcq T, Durand A, Tournoys A, Gnemmi V, Gmyr V, Pattou F, Jourdain M, Tamion F, Besnier E, Préau S, Parmentier-Decrucq E, Mathieu D, Poissy J, Favory R.

Ann Intensive Care. 2018 Feb 14;8(1):24. doi: 10.1186/s13613-018-0367-9.


Comparison of fluid balance and hemodynamic and metabolic effects of sodium lactate versus sodium bicarbonate versus 0.9% NaCl in porcine endotoxic shock: a randomized, open-label, controlled study.

Duburcq T, Durand A, Dessein AF, Vamecq J, Vienne JC, Dobbelaere D, Mention K, Douillard C, Maboudou P, Gmyr V, Pattou F, Jourdain M, Tamion F, Poissy J, Mathieu D, Favory R.

Crit Care. 2017 May 19;21(1):113. doi: 10.1186/s13054-017-1694-1.


Pharmacological approach to understanding the control of insulin secretion in human islets.

Henquin JC, Dufrane D, Gmyr V, Kerr-Conte J, Nenquin M.

Diabetes Obes Metab. 2017 Aug;19(8):1061-1070. doi: 10.1111/dom.12887. Epub 2017 Mar 31.


Human Recombinant Antithrombin (ATryn®) Administration Improves Survival and Prevents Intravascular Coagulation After Intraportal Islet Transplantation in a Piglet Model.

Gmyr V, Bonner C, Moerman E, Tournoys A, Delalleau N, Quenon A, Thevenet J, Chetboun M, Kerr-Conte J, Pattou F, Hubert T, Jourdain M.

Cell Transplant. 2017 Feb 16;26(2):309-317. doi: 10.3727/096368916X693554. Epub 2016 Oct 27.


Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL.

Plaisance V, Brajkovic S, Tenenbaum M, Favre D, Ezanno H, Bonnefond A, Bonner C, Gmyr V, Kerr-Conte J, Gauthier BR, Widmann C, Waeber G, Pattou F, Froguel P, Abderrahmani A.

PLoS One. 2016 Sep 16;11(9):e0163046. doi: 10.1371/journal.pone.0163046. eCollection 2016.


Bile Diversion in Roux-en-Y Gastric Bypass Modulates Sodium-Dependent Glucose Intestinal Uptake.

Baud G, Daoudi M, Hubert T, Raverdy V, Pigeyre M, Hervieux E, Devienne M, Ghunaim M, Bonner C, Quenon A, Pigny P, Klein A, Kerr-Conte J, Gmyr V, Caiazzo R, Pattou F.

Cell Metab. 2016 Mar 8;23(3):547-53. doi: 10.1016/j.cmet.2016.01.018. Epub 2016 Feb 25.



Duburcq T, Tournoys A, Gnemmi V, Hubert T, Gmyr V, Pattou F, Jourdain M.

Shock. 2015 Oct;44(4):341-7. doi: 10.1097/SHK.0000000000000428.


Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.

Bonner C, Kerr-Conte J, Gmyr V, Queniat G, Moerman E, Thévenet J, Beaucamps C, Delalleau N, Popescu I, Malaisse WJ, Sener A, Deprez B, Abderrahmani A, Staels B, Pattou F.

Nat Med. 2015 May;21(5):512-7. doi: 10.1038/nm.3828. Epub 2015 Apr 20.


The class I histone deacetylase inhibitor MS-275 prevents pancreatic beta cell death induced by palmitate.

Plaisance V, Rolland L, Gmyr V, Annicotte JS, Kerr-Conte J, Pattou F, Abderrahmani A.

J Diabetes Res. 2014;2014:195739. doi: 10.1155/2014/195739. Epub 2014 Dec 31.


Impact of Procedure-Related Complications on Long-term Islet Transplantation Outcome.

Caiazzo R, Vantyghem MC, Raverdi V, Bonner C, Gmyr V, Defrance F, Leroy C, Sergent G, Hubert T, Ernst O, Noel C, Kerr-Conte J, Pattou F.

Transplantation. 2015 May;99(5):979-84. doi: 10.1097/TP.0000000000000458.


Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock.

Duburcq T, Favory R, Mathieu D, Hubert T, Mangalaboyi J, Gmyr V, Quintane L, Maboudou P, Pattou F, Jourdain M.

Crit Care. 2014 Aug 14;18(4):467. doi: 10.1186/s13054-014-0467-3.


JNK3 is required for the cytoprotective effect of exendin 4.

Ezanno H, Pawlowski V, Abdelli S, Boutry R, Gmyr V, Kerr-Conte J, Bonny C, Pattou F, Abderrahmani A.

J Diabetes Res. 2014;2014:814854. doi: 10.1155/2014/814854. Epub 2014 Jun 16.


Improvement of electrophysiological neuropathy after islet transplantation for type 1 diabetes: a 5-year prospective study.

Vantyghem MC, Quintin D, Caiazzo R, Leroy C, Raverdy V, Cassim F, Glowacki F, Hubert T, Gmyr V, Noel C, Kerr-Conte J, Pattou F.

Diabetes Care. 2014 Jun;37(6):e141-2. doi: 10.2337/dc14-0320. No abstract available.


Impact of endotoxin challenge in obese pigs.

Duburcq T, Hubert T, Saint-Léger P, Mangalaboyi J, Favory R, Gmyr V, Quintane L, Tailleux A, Staels B, Tournoys A, Pattou F, Jourdain M.

Shock. 2014 Jun;41(6):546-53. doi: 10.1097/SHK.0000000000000158.


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