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Items: 1 to 20 of 52


A joint molecular networking study of a Smenospongia sponge and a cyanobacterial bloom revealed new antiproliferative chlorinated polyketides.

Teta R, Sala GD, Esposito G, Via CW, Mazzoccoli C, Piccoli C, Bertin MJ, Costantino V, Mangoni A.

Org Chem Front. 2019 Jun 7;6(11):1762-1774. doi: 10.1039/C9QO00074G. Epub 2019 Apr 11.


Fast Detection of Two Smenamide Family Members Using Molecular Networking.

Caso A, Esposito G, Della Sala G, Pawlik JR, Teta R, Mangoni A, Costantino V.

Mar Drugs. 2019 Oct 30;17(11). pii: E618. doi: 10.3390/md17110618.


Losartan through Hsp70 Avoids Angiotensin II Induced Mesenchymal Epithelial Transition in Proximal Tubule Cells from Spontaneously Hypertensive Rats.

Costantino VV, Bocanegra V, Cacciamani V, Lorenzo AFG, Benardon ME, Vallés PG.

Cell Physiol Biochem. 2019;53(4):713-730. doi: 10.33594/000000167.


A Collection of Bioactive Nitrogen-Containing Molecules from the Marine Sponge Acanthostrongylophora ingens.

Esposito G, Mai LH, Longeon A, Mangoni A, Durieu E, Meijer L, Van Soest R, Costantino V, Bourguet-Kondracki ML.

Mar Drugs. 2019 Aug 15;17(8). pii: E472. doi: 10.3390/md17080472.


Rab7b participation on the TLR4 (Toll-like receptor) endocytic pathway in Shiga toxin-associated Hemolytic Uremic Syndrome (HUS).

Lafalla Manzano AF, Gil Lorenzo AF, Bocanegra V, Costantino VV, Cacciamani V, Benardon ME, Vallés PG.

Cytokine. 2019 Sep;121:154732. doi: 10.1016/j.cyto.2019.05.019. Epub 2019 May 30.


A Fast Detection Strategy for Cyanobacterial blooms and associated cyanotoxins (FDSCC) reveals the occurrence of lyngbyatoxin A in campania (South Italy).

Esposito G, Teta R, Marrone R, De Sterlich C, Casazza M, Anastasio A, Lega M, Costantino V.

Chemosphere. 2019 Jun;225:342-351. doi: 10.1016/j.chemosphere.2019.02.201. Epub 2019 Mar 8.


Clogging the Ubiquitin-Proteasome Machinery with Marine Natural Products: Last Decade Update.

Della Sala G, Agriesti F, Mazzoccoli C, Tataranni T, Costantino V, Piccoli C.

Mar Drugs. 2018 Nov 26;16(12). pii: E467. doi: 10.3390/md16120467. Review.


Isolation of Smenopyrone, a Bis-γ-Pyrone Polypropionate from the Caribbean Sponge Smenospongia aurea.

Esposito G, Teta R, Della Sala G, Pawlik JR, Mangoni A, Costantino V.

Mar Drugs. 2018 Aug 17;16(8). pii: E285. doi: 10.3390/md16080285.


Smenamide A Analogues. Synthesis and Biological Activity on Multiple Myeloma Cells.

Caso A, Laurenzana I, Lamorte D, Trino S, Esposito G, Piccialli V, Costantino V.

Mar Drugs. 2018 Jun 13;16(6). pii: E206. doi: 10.3390/md16060206.


Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs.

D'Errico S, Borbone N, Catalanotti B, Secondo A, Petrozziello T, Piccialli I, Pannaccione A, Costantino V, Mayol L, Piccialli G, Oliviero G.

Mar Drugs. 2018 Mar 10;16(3). pii: E89. doi: 10.3390/md16030089.


Identification and chemical characterization of N-acyl-homoserine lactone quorum sensing signals across sponge species and time.

Britstein M, Saurav K, Teta R, Sala GD, Bar-Shalom R, Stoppelli N, Zoccarato L, Costantino V, Steindler L.

FEMS Microbiol Ecol. 2018 Feb 1;94(2). doi: 10.1093/femsec/fix182.


Evaluating the Effects of an Organic Extract from the Mediterranean Sponge Geodia cydonium on Human Breast Cancer Cell Lines.

Costantini S, Guerriero E, Teta R, Capone F, Caso A, Sorice A, Romano G, Ianora A, Ruocco N, Budillon A, Costantino V, Costantini M.

Int J Mol Sci. 2017 Oct 9;18(10). pii: E2112. doi: 10.3390/ijms18102112.


Zeamide, a Glycosylinositol Phosphorylceramide with the Novel Core Arap(1β→6)Ins Motif from the Marine Sponge Svenzea zeai.

Della Sala G, Teta R, Esposito G, Pawlik JR, Mangoni A, Costantino V.

Molecules. 2017 Sep 1;22(9). pii: E1455. doi: 10.3390/molecules22091455.


Thermoactinoamide A, an Antibiotic Lipophilic Cyclopeptide from the Icelandic Thermophilic Bacterium Thermoactinomyces vulgaris.

Teta R, Marteinsson VT, Longeon A, Klonowski AM, Groben R, Bourguet-Kondracki ML, Costantino V, Mangoni A.

J Nat Prod. 2017 Sep 22;80(9):2530-2535. doi: 10.1021/acs.jnatprod.7b00560. Epub 2017 Aug 25.


Studies toward the Synthesis of Smenamide A, an Antiproliferative Metabolite from Smenospongia aurea: Total Synthesis of ent-Smenamide A and 16-epi-Smenamide A.

Caso A, Mangoni A, Piccialli G, Costantino V, Piccialli V.

ACS Omega. 2017 Apr 30;2(4):1477-1488. doi: 10.1021/acsomega.7b00095. Epub 2017 Apr 17.


Cytotoxicity of Endoperoxides from the Caribbean Sponge Plakortis halichondrioides towards Sensitive and Multidrug-Resistant Leukemia Cells: Acids vs. Esters Activity Evaluation.

Schirmeister T, Oli S, Wu H, Della Sala G, Costantino V, Seo EJ, Efferth T.

Mar Drugs. 2017 Mar 3;15(3). pii: E63. doi: 10.3390/md15030063.


Plakofuranolactone as a Quorum Quenching Agent from the Indonesian Sponge Plakortis cf. lita.

Costantino V, Della Sala G, Saurav K, Teta R, Bar-Shalom R, Mangoni A, Steindler L.

Mar Drugs. 2017 Feb 28;15(3). pii: E59. doi: 10.3390/md15030059.


Quorum Sensing Inhibitors from the Sea Discovered Using Bacterial N-acyl-homoserine Lactone-Based Biosensors.

Saurav K, Costantino V, Venturi V, Steindler L.

Mar Drugs. 2017 Feb 23;15(3). pii: E53. doi: 10.3390/md15030053. Review.


Chloromethylhalicyclamine B, a Marine-Derived Protein Kinase CK1δ/ε Inhibitor.

Esposito G, Bourguet-Kondracki ML, Mai LH, Longeon A, Teta R, Meijer L, Van Soest R, Mangoni A, Costantino V.

J Nat Prod. 2016 Nov 23;79(11):2953-2960. Epub 2016 Nov 9.


In Search of Alternative Antibiotic Drugs: Quorum-Quenching Activity in Sponges and their Bacterial Isolates.

Saurav K, Bar-Shalom R, Haber M, Burgsdorf I, Oliviero G, Costantino V, Morgenstern D, Steindler L.

Front Microbiol. 2016 Apr 5;7:416. doi: 10.3389/fmicb.2016.00416. eCollection 2016.

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