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Items: 1 to 20 of 54

1.

Novel Insights on the Toxicity of Phycotoxins on the Gut through the Targeting of Enteric Glial Cells.

Reale O, Huguet A, Fessard V.

Mar Drugs. 2019 Jul 23;17(7). pii: E429. doi: 10.3390/md17070429.

2.

Three-dimensional HepaRG spheroids as a liver model to study human genotoxicity in vitro with the single cell gel electrophoresis assay.

Mandon M, Huet S, Dubreil E, Fessard V, Le Hégarat L.

Sci Rep. 2019 Jul 22;9(1):10548. doi: 10.1038/s41598-019-47114-7.

3.

Pinnatoxins' Deleterious Effects on Cholinergic Networks: From Experimental Models to Human Health.

Delcourt N, Lagrange E, Abadie E, Fessard V, Frémy JM, Vernoux JP, Peyrat MB, Maignien T, Arnich N, Molgó J, Mattei C.

Mar Drugs. 2019 Jul 20;17(7). pii: E425. doi: 10.3390/md17070425. Review.

4.

Simultaneous Detection of 14 Microcystin Congeners from Tissue Samples Using UPLC- ESI-MS/MS and Two Different Deuterated Synthetic Microcystins as Internal Standards.

Altaner S, Puddick J, Fessard V, Feurstein D, Zemskov I, Wittmann V, Dietrich DR.

Toxins (Basel). 2019 Jul 2;11(7). pii: E388. doi: 10.3390/toxins11070388.

5.

Combined effects of okadaic acid and pectenotoxin-2, 13-desmethylspirolide C or yessotoxin in human intestinal Caco-2 cells.

Alarcan J, Barbé S, Kopp B, Hessel-Pras S, Braeuning A, Lampen A, Le Hégarat L, Fessard V.

Chemosphere. 2019 Aug;228:139-148. doi: 10.1016/j.chemosphere.2019.04.018. Epub 2019 Apr 5.

PMID:
31029959
6.

Aluminum in liver cells - the element species matters.

Sieg H, Ellermann AL, Maria Kunz B, Jalili P, Burel A, Hogeveen K, Böhmert L, Chevance S, Braeuning A, Gauffre F, Fessard V, Lampen A.

Nanotoxicology. 2019 Sep;13(7):909-922. doi: 10.1080/17435390.2019.1593542. Epub 2019 Apr 2.

PMID:
30938204
7.

Identification of key pathways involved in the toxic response of the cyanobacterial toxin cylindrospermopsin in human hepatic HepaRG cells.

Huguet A, Lanceleur R, Quenault H, Le Hégarat L, Fessard V.

Toxicol In Vitro. 2019 Aug;58:69-77. doi: 10.1016/j.tiv.2019.03.023. Epub 2019 Mar 21.

PMID:
30905859
8.

Metabolism of the lipophilic phycotoxin 13-Desmethylspirolide C using human and rat in vitro liver models.

Alarcan J, Dubreil E, Huguet A, Aráoz R, Brée F, Bouaita B, Hurtaud-Pessel D, Braeuning A, Hessel-Pras S, Lampen A, Le Hégarat L, Fessard V.

Toxicol Lett. 2019 Jun 1;307:17-25. doi: 10.1016/j.toxlet.2019.02.012. Epub 2019 Feb 27.

PMID:
30825503
9.

Uptake and molecular impact of aluminum-containing nanomaterials on human intestinal caco-2 cells.

Sieg H, Braeuning C, Kunz BM, Daher H, Kästner C, Krause BC, Meyer T, Jalili P, Hogeveen K, Böhmert L, Lichtenstein D, Burel A, Chevance S, Jungnickel H, Tentschert J, Laux P, Braeuning A, Gauffre F, Fessard V, Meijer J, Estrela-Lopis I, Thünemann AF, Luch A, Lampen A.

Nanotoxicology. 2018 Nov;12(9):992-1013. doi: 10.1080/17435390.2018.1504999. Epub 2018 Oct 14.

PMID:
30317887
10.

Assessment of the in vitro genotoxicity of TiO2 nanoparticles in a regulatory context.

Charles S, Jomini S, Fessard V, Bigorgne-Vizade E, Rousselle C, Michel C.

Nanotoxicology. 2018 May;12(4):357-374. doi: 10.1080/17435390.2018.1451567. Epub 2018 Mar 19. Review.

PMID:
29553842
11.

Mixtures of Lipophilic Phycotoxins: Exposure Data and Toxicological Assessment.

Alarcan J, Biré R, Le Hégarat L, Fessard V.

Mar Drugs. 2018 Jan 31;16(2). pii: E46. doi: 10.3390/md16020046. Review.

12.

Nanomaterials: certain aspects of application, risk assessment and risk communication.

Laux P, Tentschert J, Riebeling C, Braeuning A, Creutzenberg O, Epp A, Fessard V, Haas KH, Haase A, Hund-Rinke K, Jakubowski N, Kearns P, Lampen A, Rauscher H, Schoonjans R, Störmer A, Thielmann A, Mühle U, Luch A.

Arch Toxicol. 2018 Jan;92(1):121-141. doi: 10.1007/s00204-017-2144-1. Epub 2017 Dec 22. Review.

13.

Genotoxic effects of food contact recycled paperboard extracts on two human hepatic cell lines.

Souton E, Severin I, Le Hegarat L, Hogeveen K, Aljawish A, Fessard V, Marie-Christine C.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Jan;35(1):159-170. doi: 10.1080/19440049.2017.1397774. Epub 2017 Nov 15.

PMID:
29076405
14.

Impact of an Artificial Digestion Procedure on Aluminum-Containing Nanomaterials.

Sieg H, Kästner C, Krause B, Meyer T, Burel A, Böhmert L, Lichtenstein D, Jungnickel H, Tentschert J, Laux P, Braeuning A, Estrela-Lopis I, Gauffre F, Fessard V, Meijer J, Luch A, Thünemann AF, Lampen A.

Langmuir. 2017 Oct 10;33(40):10726-10735. doi: 10.1021/acs.langmuir.7b02729. Epub 2017 Sep 26.

15.

Maitotoxin-4, a Novel MTX Analog Produced by Gambierdiscus excentricus.

Pisapia F, Sibat M, Herrenknecht C, Lhaute K, Gaiani G, Ferron PJ, Fessard V, Fraga S, Nascimento SM, Litaker RW, Holland WC, Roullier C, Hess P.

Mar Drugs. 2017 Jul 11;15(7). pii: E220. doi: 10.3390/md15070220.

16.

Metabolism of the Marine Phycotoxin PTX-2 and Its Effects on Hepatic Xenobiotic Metabolism: Activation of Nuclear Receptors and Modulation of the Phase I Cytochrome P450.

Alarcan J, Dubreil E, Huguet A, Hurtaud-Pessel D, Hessel-Pras S, Lampen A, Fessard V, Le Hegarat L.

Toxins (Basel). 2017 Jul 5;9(7). pii: E212. doi: 10.3390/toxins9070212.

17.

High throughput toxicity screening and intracellular detection of nanomaterials.

Collins AR, Annangi B, Rubio L, Marcos R, Dorn M, Merker C, Estrela-Lopis I, Cimpan MR, Ibrahim M, Cimpan E, Ostermann M, Sauter A, Yamani NE, Shaposhnikov S, Chevillard S, Paget V, Grall R, Delic J, de-Cerio FG, Suarez-Merino B, Fessard V, Hogeveen KN, Fjellsbø LM, Pran ER, Brzicova T, Topinka J, Silva MJ, Leite PE, Ribeiro AR, Granjeiro JM, Grafström R, Prina-Mello A, Dusinska M.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Jan;9(1). doi: 10.1002/wnan.1413. Epub 2016 Jun 7. Review.

18.

Combined Effects of Lipophilic Phycotoxins (Okadaic Acid, Azapsiracid-1 and Yessotoxin) on Human Intestinal Cells Models.

Ferron PJ, Dumazeau K, Beaulieu JF, Le Hégarat L, Fessard V.

Toxins (Basel). 2016 Feb 19;8(2):50. doi: 10.3390/toxins8020050.

19.

In vitro metabolism of the cyanotoxin cylindrospermopsin in HepaRG cells and liver tissue fractions.

Kittler K, Hurtaud-Pessel D, Maul R, Kolrep F, Fessard V.

Toxicon. 2016 Feb;110:47-50. doi: 10.1016/j.toxicon.2015.11.007. Epub 2015 Dec 2.

PMID:
26610396
20.

Genotoxicity of synthetic amorphous silica nanoparticles in rats following short-term exposure. Part 1: oral route.

Tarantini A, Huet S, Jarry G, Lanceleur R, Poul M, Tavares A, Vital N, Louro H, João Silva M, Fessard V.

Environ Mol Mutagen. 2015 Mar;56(2):218-27. doi: 10.1002/em.21935. Epub 2014 Dec 15.

PMID:
25504566

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