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Items: 1 to 20 of 68


Self-DNA Sensing in Lung Inflammatory Diseases.

Benmerzoug S, Ryffel B, Togbe D, Quesniaux VFJ.

Trends Immunol. 2019 Aug;40(8):719-734. doi: 10.1016/ Epub 2019 Jun 28. Review.


Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity.

Benmerzoug S, Bounab B, Rose S, Gosset D, Biet F, Cochard T, Xavier A, Rouxel N, Fauconnier L, Horsnell WGC, Ryffel B, Togbe D, Quesniaux VFJ.

Cell Rep. 2019 May 28;27(9):2649-2664.e5. doi: 10.1016/j.celrep.2019.04.110.


Myeloid cell TNFR1 signaling dependent liver injury and inflammation upon BCG infection.

Chavez-Galan L, Vesin D, Blaser G, Uysal H, Benmerzoug S, Rose S, Ryffel B, Quesniaux VFJ, Garcia I.

Sci Rep. 2019 Mar 28;9(1):5297. doi: 10.1038/s41598-019-41629-9.


STING-dependent sensing of self-DNA drives silica-induced lung inflammation.

Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, Mollet L, Le Bert M, Lambers C, Geleff S, Roth M, Fauconnier L, Sedda D, Carvalho C, Perche O, Laurenceau D, Ryffel B, Apetoh L, Kiziltunc A, Uslu H, Albez FS, Akgun M, Togbe D, Quesniaux VFJ.

Nat Commun. 2018 Dec 6;9(1):5226. doi: 10.1038/s41467-018-07425-1.


Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy.

Uysal H, Chavez-Galan L, Vesin D, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I.

Int J Mol Sci. 2018 Jul 4;19(7). pii: E1959. doi: 10.3390/ijms19071959.


G-quadruplex DNA targeting alters class-switch recombination in B cells and attenuates allergic inflammation.

Dalloul Z, Chenuet P, Dalloul I, Boyer F, Aldigier JC, Laffleur B, El Makhour Y, Ryffel B, Quesniaux VFJ, Togbé D, Mergny JL, Cook-Moreau J, Cogné M.

J Allergy Clin Immunol. 2018 Oct;142(4):1352-1355. doi: 10.1016/j.jaci.2018.06.011. Epub 2018 Jun 20. No abstract available.


GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection.

Benmerzoug S, Marinho FV, Rose S, Mackowiak C, Gosset D, Sedda D, Poisson E, Uyttenhove C, Van Snick J, Jacobs M, Garcia I, Ryffel B, Quesniaux VFJ.

Sci Rep. 2018 Jun 5;8(1):8652. doi: 10.1038/s41598-018-26984-3.


The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection.

Marinho FV, Benmerzoug S, Rose S, Campos PC, Marques JT, Báfica A, Barber G, Ryffel B, Oliveira SC, Quesniaux VFJ.

J Innate Immun. 2018;10(3):239-252. doi: 10.1159/000488952. Epub 2018 May 23.


Cell iron status influences macrophage polarization.

Agoro R, Taleb M, Quesniaux VFJ, Mura C.

PLoS One. 2018 May 17;13(5):e0196921. doi: 10.1371/journal.pone.0196921. eCollection 2018.


MyD88 as a therapeutic target for inflammatory lung diseases.

Di Padova F, Quesniaux VFJ, Ryffel B.

Expert Opin Ther Targets. 2018 May;22(5):401-408. doi: 10.1080/14728222.2018.1464139. Epub 2018 Apr 20. Review.


An Iron-Rich Diet Decreases the Mycobacterial Burden and Correlates With Hepcidin Upregulation, Lower Levels of Proinflammatory Mediators, and Increased T-Cell Recruitment in a Model of Mycobacterium bovis Bacille Calmette-Guerin Infection.

Agoro R, Benmerzoug S, Rose S, Bouyer M, Gozzelino R, Garcia I, Ryffel B, Quesniaux VFJ, Mura C.

J Infect Dis. 2017 Oct 17;216(7):907-918. doi: 10.1093/infdis/jix366.


Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy.

Chavez-Galan L, Vesin D, Uysal H, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I.

Front Immunol. 2017 Aug 25;8:999. doi: 10.3389/fimmu.2017.00999. eCollection 2017.


IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria.

Reverchon F, Mortaud S, Sivoyon M, Maillet I, Laugeray A, Palomo J, Montécot C, Herzine A, Meme S, Meme W, Erard F, Ryffel B, Menuet A, Quesniaux VFJ.

PLoS Pathog. 2017 Apr 27;13(4):e1006322. doi: 10.1371/journal.ppat.1006322. eCollection 2017 Apr.


Bioengineered 3D Models for Studying Human Cell-Tuberculosis Interactions.

Benmerzoug S, Quesniaux VFJ.

Trends Microbiol. 2017 Apr;25(4):245-246. doi: 10.1016/j.tim.2017.02.009. Epub 2017 Mar 8.


Myeloid and T Cell-Derived TNF Protects against Central Nervous System Tuberculosis.

Hsu NJ, Francisco NM, Keeton R, Allie N, Quesniaux VF, Ryffel B, Jacobs M.

Front Immunol. 2017 Feb 23;8:180. doi: 10.3389/fimmu.2017.00180. eCollection 2017.


Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation.

Dambuza IM, Keeton R, Hsu NJ, Allie N, Quesniaux VF, Ryffel B, Jacobs M.

Sci Rep. 2016 Dec 20;6:39499. doi: 10.1038/srep39499.


Protein kinase Cθ controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen.

Madouri F, Chenuet P, Beuraud C, Fauconnier L, Marchiol T, Rouxel N, Ledru A, Gallerand M, Lombardi V, Mascarell L, Marquant Q, Apetoh L, Erard F, Le Bert M, Trovero F, Quesniaux VFJ, Ryffel B, Togbe D.

J Allergy Clin Immunol. 2017 May;139(5):1650-1666. doi: 10.1016/j.jaci.2016.08.044. Epub 2016 Oct 14.


Glufosinate aerogenic exposure induces glutamate and IL-1 receptor dependent lung inflammation.

Maillet I, Perche O, Pâris A, Richard O, Gombault A, Herzine A, Pichon J, Huaux F, Mortaud S, Ryffel B, Quesniaux VF, Montécot-Dubourg C.

Clin Sci (Lond). 2016 Nov 1;130(21):1939-54. doi: 10.1042/CS20160530. Epub 2016 Aug 22.


Tumor Necrosis Factor and Its Receptors Are Crucial to Control Mycobacterium bovis Bacillus Calmette-Guerin Pleural Infection in a Murine Model.

Chavez-Galan L, Vesin D, Segueni N, Prasad P, Buser-Llinares R, Blaser G, Pache JC, Ryffel B, Quesniaux VF, Garcia I.

Am J Pathol. 2016 Sep;186(9):2364-77. doi: 10.1016/j.ajpath.2016.05.015. Epub 2016 Jul 25.


Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection.

Segueni N, Benmerzoug S, Rose S, Gauthier A, Bourigault ML, Reverchon F, Philippeau A, Erard F, Le Bert M, Bouscayrol H, Wachter T, Garcia I, Kollias G, Jacobs M, Ryffel B, Quesniaux VF.

Sci Rep. 2016 Mar 2;6:22454. doi: 10.1038/srep22454.

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