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Items: 1 to 20 of 48

1.

PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation.

Wimmer I, Tietz S, Nishihara H, Deutsch U, Sallusto F, Gosselet F, Lyck R, Muller WA, Lassmann H, Engelhardt B.

Front Immunol. 2019 Apr 5;10:711. doi: 10.3389/fimmu.2019.00711. eCollection 2019.

2.

The Genetic Background of Mice Influences the Effects of Cigarette Smoke on Onset and Severity of Experimental Autoimmune Encephalomyelitis.

Enzmann G, Adelfio R, Godel A, Haghayegh Jahromi N, Tietz S, Burgener SS, Deutsch U, Wekerle H, Benarafa C, Engelhardt B.

Int J Mol Sci. 2019 Mar 21;20(6). pii: E1433. doi: 10.3390/ijms20061433.

3.

Claudin-3-deficient C57BL/6J mice display intact brain barriers.

Castro Dias M, Coisne C, Lazarevic I, Baden P, Hata M, Iwamoto N, Francisco DMF, Vanlandewijck M, He L, Baier FA, Stroka D, Bruggmann R, Lyck R, Enzmann G, Deutsch U, Betsholtz C, Furuse M, Tsukita S, Engelhardt B.

Sci Rep. 2019 Jan 18;9(1):203. doi: 10.1038/s41598-018-36731-3.

4.

Lack of junctional adhesion molecule (JAM)-B ameliorates experimental autoimmune encephalomyelitis.

Tietz S, Périnat T, Greene G, Enzmann G, Deutsch U, Adams R, Imhof B, Aurrand-Lions M, Engelhardt B.

Brain Behav Immun. 2018 Oct;73:3-20. doi: 10.1016/j.bbi.2018.06.014. Epub 2018 Jun 18.

PMID:
29920328
5.

A Novel Cervical Spinal Cord Window Preparation Allows for Two-Photon Imaging of T-Cell Interactions with the Cervical Spinal Cord Microvasculature during Experimental Autoimmune Encephalomyelitis.

Haghayegh Jahromi N, Tardent H, Enzmann G, Deutsch U, Kawakami N, Bittner S, Vestweber D, Zipp F, Stein JV, Engelhardt B.

Front Immunol. 2017 Apr 11;8:406. doi: 10.3389/fimmu.2017.00406. eCollection 2017.

6.

Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis.

Fan Z, McArdle S, Marki A, Mikulski Z, Gutierrez E, Engelhardt B, Deutsch U, Ginsberg M, Groisman A, Ley K.

Nat Commun. 2016 Aug 31;7:12658. doi: 10.1038/ncomms12658.

7.

ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood-brain barrier.

Lyck R, Lécuyer MA, Abadier M, Wyss CB, Matti C, Rosito M, Enzmann G, Zeis T, Michel L, García Martín AB, Sallusto F, Gosselet F, Deutsch U, Weiner JA, Schaeren-Wiemers N, Prat A, Engelhardt B.

J Cereb Blood Flow Metab. 2017 Aug;37(8):2894-2909. doi: 10.1177/0271678X16678639. Epub 2016 Nov 14.

8.

ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome.

Broggini T, Czabanka M, Piffko A, Harms C, Hoffmann C, Mrowka R, Wenke F, Deutsch U, Grötzinger C, Vajkoczy P.

Eur Spine J. 2015 Oct;24(10):2173-81. doi: 10.1007/s00586-015-3811-7. Epub 2015 Feb 25.

PMID:
25711910
9.

Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier.

Abadier M, Haghayegh Jahromi N, Cardoso Alves L, Boscacci R, Vestweber D, Barnum S, Deutsch U, Engelhardt B, Lyck R.

Eur J Immunol. 2015 Apr;45(4):1043-58. doi: 10.1002/eji.201445125. Epub 2015 Jan 23.

10.
11.

Postnatal Notch1 activation induces T‑cell malignancy in conditional and inducible mouse models.

Liu J, Dong F, Fung I, Chen E, Allen TD, Deutsch U, Lobe CG.

Int J Oncol. 2014 Nov;45(5):1997-2004. doi: 10.3892/ijo.2014.2626. Epub 2014 Aug 29.

PMID:
25175815
12.

Constitutive notch signaling in adult transgenic mice inhibits bFGF-induced angiogenesis and blocks ovarian follicle development.

Liu J, Deutsch U, Jeong J, Lobe CG.

Genesis. 2014 Sep;52(9):809-16. doi: 10.1002/dvg.22790. Epub 2014 May 29.

PMID:
24817584
13.

PSGL-1 and E/P-selectins are essential for T-cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE.

Sathiyanadan K, Coisne C, Enzmann G, Deutsch U, Engelhardt B.

Eur J Immunol. 2014 Aug;44(8):2287-94. doi: 10.1002/eji.201344214. Epub 2014 May 11.

14.

DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation.

Minten C, Alt C, Gentner M, Frei E, Deutsch U, Lyck R, Schaeren-Wiemers N, Rot A, Engelhardt B.

Brain. 2014 May;137(Pt 5):1454-69. doi: 10.1093/brain/awu045. Epub 2014 Mar 12.

15.

Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis.

Ziegler T, Horstkotte J, Schwab C, Pfetsch V, Weinmann K, Dietzel S, Rohwedder I, Hinkel R, Gross L, Lee S, Hu J, Soehnlein O, Franz WM, Sperandio M, Pohl U, Thomas M, Weber C, Augustin HG, Fässler R, Deutsch U, Kupatt C.

J Clin Invest. 2013 Jul 1. pii: 66549. doi: 10.1172/JCI66549. [Epub ahead of print]

16.

Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus.

Wyss L, Schäfer J, Liebner S, Mittelbronn M, Deutsch U, Enzmann G, Adams RH, Aurrand-Lions M, Plate KH, Imhof BA, Engelhardt B.

PLoS One. 2012;7(9):e45619. doi: 10.1371/journal.pone.0045619. Epub 2012 Sep 18.

17.

Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis.

Pfeiffer F, Schäfer J, Lyck R, Makrides V, Brunner S, Schaeren-Wiemers N, Deutsch U, Engelhardt B.

Acta Neuropathol. 2011 Nov;122(5):601-14. doi: 10.1007/s00401-011-0883-2. Epub 2011 Oct 9.

18.

TET inducible expression of the α4β7-integrin ligand MAdCAM-1 on the blood-brain barrier does not influence the immunopathogenesis of experimental autoimmune encephalomyelitis.

Döring A, Pfeiffer F, Meier M, Dehouck B, Tauber S, Deutsch U, Engelhardt B.

Eur J Immunol. 2011 Mar;41(3):813-21. doi: 10.1002/eji.201040912. Epub 2011 Feb 10.

19.

PSGL-1 is dispensible for the development of active experimental autoimmune encephalomyelitis in SJL/J mice.

Bill R, Döring A, Deutsch U, Engelhardt B.

J Neuroimmunol. 2011 Mar;232(1-2):207-8. doi: 10.1016/j.jneuroim.2010.10.008. Epub 2010 Nov 3.

PMID:
21051092
20.

Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium.

Steiner O, Coisne C, Cecchelli R, Boscacci R, Deutsch U, Engelhardt B, Lyck R.

J Immunol. 2010 Oct 15;185(8):4846-55. doi: 10.4049/jimmunol.0903732. Epub 2010 Sep 22.

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