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J Pediatr Surg. 2015 Sep;50(9):1441-56. doi: 10.1016/j.jpedsurg.2015.01.004. Epub 2015 Jan 16.

A cross-sectional nationwide survey on esophageal atresia and tracheoesophageal fistula.

Author information

1
Istituto Giannina Gaslini, Genova, Italy. Electronic address: a.piniprato@gmail.com.
2
Istituto Giannina Gaslini, Genova, Italy.
3
Ospedale Pediatrico Bambino Gesù, Roma, Italy.
4
Azienda Ospedaliero-Universitaria, Padova, Italy.
5
Azienda Ospedaliera della Provincia di Lecco, Merate, Italy.
6
Ospedale Maggiore Policlinico Magiagalli, Milano, Italy.
7
Ospedale Giovanni XXIII, Bari, Italy.
8
Policlinico Gemelli, Roma, Italy.
9
Ospedale Pediatrico Meyer, Firenze, Italy.
10
Azienda Ospedaliera Pediatrica Santobono Pausilipon, Napoli, Italy.
11
Istituto Giannina Gaslini, Genova, Italy; Università degli Studi di Genova, Genova, Italy.
12
ASN SS: Antonio e Biagio e Cesare Arrigo, Alessandria.
13
Ospedali Riuniti, Bergamo.
14
Spedali Civili, Brescia.
15
Ospedale dei Bambini V. Buzzi, Milano.
16
Ospedale Niguarda Ca' Granda, Milano.
17
Ospedale San Carlo Borromeo, Milano.
18
Policlinico San Matteo, Pavia.
19
Ospedale Infantile Regina Margherita, Torino.
20
Ospedale Sant'Orsola Malpighi, Bologna.
21
Ospedale di Bolzano.
22
Archispedale Sant'Anna, Ferrara.
23
Ospedale Policlinico, Modena.
24
Azienda Ospedalier-Universitaria, Parma.
25
Ospedale Infermi, Rimini.
26
Ospedale Santa Chiara, Trento.
27
Ospedale Regionale, Treviso.
28
Ospedale Infantile Burlo Garofalo, Trieste.
29
Policlinico Borgo Roma, Verona.
30
Ospedale San Bortolo, Vicenza.
31
Ospedale Salesi, Ancona.
32
Ospedale Santa Maria della Misericordia, Perugia.
33
Ospedale San Camillo Forlanini, Roma.
34
Ospedale Policlinico Sant'Andrea, Roma.
35
Policlinico Umberto I, Roma.
36
Ospedale Policlinico Santa Maria alle Scotte, Siena.
37
Ospedale Policlinico, Bari.
38
Ospedale Francesco Ferrari, Casarano.
39
Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro.
40
Azienda Ospedaliera di Cosenza, Cosenza.
41
Azienda Ospedaliera Universitaria-Ospedali Riuniti, Foggia.
42
Azienda Ospedaliero-Universitaria G. Martino, Messina.
43
Policlinico Universitario Federico II, Napoli.
44
Ospedale Santo Spirito, Pescara.
45
Azienda Ospedaliera Universitaria S. Giovanni di Dio e Ruggi d'Aragona, Salerno.
46
Ospedale SS. Trinita', Cagliari.
47
Ospedale Garibaldi, Catania.
48
Ospedale Vittorio Emanuele, Catania.
49
Presdio Ospedaliero CTO, Iglesias.
50
Azienda Ospedaliero-Universitaria Policlinico P. Giaccone.
51
Azienda Ospedaliero-Universitaria, Sassari.
52
Ospedale Sant'Antonio Abate, Trapani.
53
Ospedale Maggiore della carità, Novara.

Abstract

BACKGROUND:

Our study aims at disclosing epidemiology and most relevant clinical features of esophageal atresia (EA) pointing to a model of multicentre collaboration.

METHODS:

A detailed questionnaire was sent to all Italian Units of pediatric surgery in order to collect data of patients born with EA between January and December 2012. The results were crosschecked by matching date and place of birth of the patients with those of diagnosis-related group provided by the Italian Ministry of Health (MOH).

RESULTS:

A total of 146 questionnaires were returned plus a further 32 patients reported in the MOH database. Basing on a total of 178 patients with EA born in Italy in 2012, the incidence of EA was calculated in 3.33 per 10,000 live births. Antenatal diagnosis was suspected in 29.5% patients. 55.5% showed associated anomalies. The most common type of EA was Gross type C (89%). Postoperative complications occurred in 37% of type C EA and 100% of type A EA. A 9.5% mortality rate was reported.

CONCLUSIONS:

This is the first Italian cross-sectional nationwide survey on EA. We can now develop shared guidelines and provide more reliable prognostic expectations for our patients.

KEYWORDS:

Cross-sectional; Diagnosis; Esophageal atresia; Management; Mortality; Nationwide survey

PMID:
25783403
DOI:
10.1016/j.jpedsurg.2015.01.004
[Indexed for MEDLINE]

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