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Items: 1 to 20 of 56


Okadaic acid activates Wnt/β-catenin-signaling in human HepaRG cells.

Dietrich J, Sommersdorf C, Gohlke S, Poetz O, Traenkle B, Rothbauer U, Hessel-Pras S, Lampen A, Braeuning A.

Arch Toxicol. 2019 Jul;93(7):1927-1939. doi: 10.1007/s00204-019-02489-4. Epub 2019 May 21.


Chromobodies to Quantify Changes of Endogenous Protein Concentration in Living Cells.

Keller BM, Maier J, Secker KA, Egetemaier SM, Parfyonova Y, Rothbauer U, Traenkle B.

Mol Cell Proteomics. 2018 Dec;17(12):2518-2533. doi: 10.1074/mcp.TIR118.000914. Epub 2018 Sep 18.


Speed up to find the right ones: rapid discovery of functional nanobodies.

Rothbauer U.

Nat Struct Mol Biol. 2018 Mar;25(3):199-201. doi: 10.1038/s41594-018-0038-4. No abstract available.


A peptide tag-specific nanobody enables high-quality labeling for dSTORM imaging.

Virant D, Traenkle B, Maier J, Kaiser PD, Bodenhöfer M, Schmees C, Vojnovic I, Pisak-Lukáts B, Endesfelder U, Rothbauer U.

Nat Commun. 2018 Mar 2;9(1):930. doi: 10.1038/s41467-018-03191-2.


Akt1 and Akt3 but not Akt2 through interaction with DNA-PKcs stimulate proliferation and post-irradiation cell survival of K-RAS-mutated cancer cells.

Toulany M, Maier J, Iida M, Rebholz S, Holler M, Grottke A, Jüker M, Wheeler DL, Rothbauer U, Rodemann HP.

Cell Death Discov. 2017 Oct 30;3:17072. doi: 10.1038/cddiscovery.2017.72. eCollection 2017.


Under the Microscope: Single-Domain Antibodies for Live-Cell Imaging and Super-Resolution Microscopy.

Traenkle B, Rothbauer U.

Front Immunol. 2017 Aug 24;8:1030. doi: 10.3389/fimmu.2017.01030. eCollection 2017. Review.


Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer.

Sannino G, Armbruster N, Bodenhöfer M, Haerle U, Behrens D, Buchholz M, Rothbauer U, Sipos B, Schmees C.

Oncotarget. 2016 Nov 8;7(45):73725-73738. doi: 10.18632/oncotarget.12455.


Visualizing Epithelial-Mesenchymal Transition Using the Chromobody Technology.

Maier J, Traenkle B, Rothbauer U.

Cancer Res. 2016 Oct 1;76(19):5592-5596. Epub 2016 Sep 15. Review.


A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib.

Sinnberg T, Makino E, Krueger MA, Velic A, Macek B, Rothbauer U, Groll N, Pötz O, Czemmel S, Niessner H, Meier F, Ikenberg K, Garbe C, Schittek B.

EBioMedicine. 2016 Jun;8:132-149. doi: 10.1016/j.ebiom.2016.04.037. Epub 2016 May 1.


Coordinate regulation of Cyp2e1 by β-catenin- and hepatocyte nuclear factor 1α-dependent signaling.

Groll N, Petrikat T, Vetter S, Colnot S, Weiss F, Poetz O, Joos TO, Rothbauer U, Schwarz M, Braeuning A.

Toxicology. 2016 Mar 28;350-352:40-8. doi: 10.1016/j.tox.2016.05.004. Epub 2016 May 3.


A Multiplexed High-Content Screening Approach Using the Chromobody Technology to Identify Cell Cycle Modulators in Living Cells.

Schorpp K, Rothenaigner I, Maier J, Traenkle B, Rothbauer U, Hadian K.

J Biomol Screen. 2016 Oct;21(9):965-77. doi: 10.1177/1087057116641935. Epub 2016 Apr 4.


A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human Cells.

Buchfellner A, Yurlova L, Nüske S, Scholz AM, Bogner J, Ruf B, Zolghadr K, Drexler SE, Drexler GA, Girst S, Greubel C, Reindl J, Siebenwirth C, Romer T, Friedl AA, Rothbauer U.

PLoS One. 2016 Mar 7;11(3):e0151041. doi: 10.1371/journal.pone.0151041. eCollection 2016.


Peptides in headlock--a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy.

Braun MB, Traenkle B, Koch PA, Emele F, Weiss F, Poetz O, Stehle T, Rothbauer U.

Sci Rep. 2016 Jan 21;6:19211. doi: 10.1038/srep19211.


From Enzyme to Whole Blood: Sequential Screening Procedure for Identification and Evaluation of p38 MAPK Inhibitors.

Bauer SM, Kubiak JM, Rothbauer U, Laufer S.

Methods Mol Biol. 2016;1360:123-48. doi: 10.1007/978-1-4939-3073-9_10.


Generation of an alpaca-derived nanobody recognizing γ-H2AX.

Rajan M, Mortusewicz O, Rothbauer U, Hastert FD, Schmidthals K, Rapp A, Leonhardt H, Cardoso MC.

FEBS Open Bio. 2015 Sep 21;5:779-88. doi: 10.1016/j.fob.2015.09.005. eCollection 2015.


Real-time analysis of epithelial-mesenchymal transition using fluorescent single-domain antibodies.

Maier J, Traenkle B, Rothbauer U.

Sci Rep. 2015 Aug 21;5:13402. doi: 10.1038/srep13402.


Live imaging of endogenous protein dynamics in zebrafish using chromobodies.

Panza P, Maier J, Schmees C, Rothbauer U, Söllner C.

Development. 2015 May 15;142(10):1879-84. doi: 10.1242/dev.118943.


Towards multiplexed protein-protein interaction analysis using protein tag-specific nanobodies.

Groll N, Emele F, Poetz O, Rothbauer U.

J Proteomics. 2015 Sep 8;127(Pt B):289-99. doi: 10.1016/j.jprot.2015.04.017. Epub 2015 May 1.


Correction to Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases.

Muth F, Günther M, Bauer SM, Döring E, Fischer S, Maier J, Drückes P, Köppler J, Trappe J, Rothbauer U, Koch P, Laufer SA.

J Med Chem. 2015 Mar 12;58(5):2567. doi: 10.1021/acs.jmedchem.5b00235. Epub 2015 Feb 26. No abstract available.


Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells.

Traenkle B, Emele F, Anton R, Poetz O, Haeussler RS, Maier J, Kaiser PD, Scholz AM, Nueske S, Buchfellner A, Romer T, Rothbauer U.

Mol Cell Proteomics. 2015 Mar;14(3):707-23. doi: 10.1074/mcp.M114.044016. Epub 2015 Jan 16.

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