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Items: 1 to 20 of 49

1.

Strategies to establish the link between biosynthetic gene clusters and secondary metabolites.

Kjærbølling I, Mortensen UH, Vesth T, Andersen MR.

Fungal Genet Biol. 2019 Sep;130:107-121. doi: 10.1016/j.fgb.2019.06.001. Epub 2019 Jun 10. Review.

2.

Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri.

Vesth TC, Nybo JL, Theobald S, Frisvad JC, Larsen TO, Nielsen KF, Hoof JB, Brandl J, Salamov A, Riley R, Gladden JM, Phatale P, Nielsen MT, Lyhne EK, Kogle ME, Strasser K, McDonnell E, Barry K, Clum A, Chen C, LaButti K, Haridas S, Nolan M, Sandor L, Kuo A, Lipzen A, Hainaut M, Drula E, Tsang A, Magnuson JK, Henrissat B, Wiebenga A, Simmons BA, Mäkelä MR, de Vries RP, Grigoriev IV, Mortensen UH, Baker SE, Andersen MR.

Nat Genet. 2018 Dec;50(12):1688-1695. doi: 10.1038/s41588-018-0246-1. Epub 2018 Oct 22.

PMID:
30349117
3.

Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans.

Frandsen RJN, Khorsand-Jamal P, Kongstad KT, Nafisi M, Kannangara RM, Staerk D, Okkels FT, Binderup K, Madsen B, Møller BL, Thrane U, Mortensen UH.

Sci Rep. 2018 Aug 27;8(1):12853. doi: 10.1038/s41598-018-30816-9.

4.

Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation.

Matsuda Y, Bai T, Phippen CBW, Nødvig CS, Kjærbølling I, Vesth TC, Andersen MR, Mortensen UH, Gotfredsen CH, Abe I, Larsen TO.

Nat Commun. 2018 Jul 3;9(1):2587. doi: 10.1038/s41467-018-04983-2.

5.

Genome Editing: CRISPR-Cas9.

Hoof JB, Nødvig CS, Mortensen UH.

Methods Mol Biol. 2018;1775:119-132. doi: 10.1007/978-1-4939-7804-5_11.

PMID:
29876814
6.

On the biosynthetic origin of carminic acid.

Rasmussen SA, Kongstad KT, Khorsand-Jamal P, Kannangara RM, Nafisi M, Van Dam A, Bennedsen M, Madsen B, Okkels F, Gotfredsen CH, Staerk D, Thrane U, Mortensen UH, Larsen TO, Frandsen RJN.

Insect Biochem Mol Biol. 2018 May;96:51-61. doi: 10.1016/j.ibmb.2018.03.002. Epub 2018 Mar 16.

7.

Efficient oligo nucleotide mediated CRISPR-Cas9 gene editing in Aspergilli.

Nødvig CS, Hoof JB, Kogle ME, Jarczynska ZD, Lehmbeck J, Klitgaard DK, Mortensen UH.

Fungal Genet Biol. 2018 Jun;115:78-89. doi: 10.1016/j.fgb.2018.01.004. Epub 2018 Jan 8.

PMID:
29325827
8.

Linking secondary metabolites to gene clusters through genome sequencing of six diverse Aspergillus species.

Kjærbølling I, Vesth TC, Frisvad JC, Nybo JL, Theobald S, Kuo A, Bowyer P, Matsuda Y, Mondo S, Lyhne EK, Kogle ME, Clum A, Lipzen A, Salamov A, Ngan CY, Daum C, Chiniquy J, Barry K, LaButti K, Haridas S, Simmons BA, Magnuson JK, Mortensen UH, Larsen TO, Grigoriev IV, Baker SE, Andersen MR.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E753-E761. doi: 10.1073/pnas.1715954115. Epub 2018 Jan 9.

9.

Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper.

Meyer V, Andersen MR, Brakhage AA, Braus GH, Caddick MX, Cairns TC, de Vries RP, Haarmann T, Hansen K, Hertz-Fowler C, Krappmann S, Mortensen UH, Peñalva MA, Ram AFJ, Head RM.

Fungal Biol Biotechnol. 2016 Aug 31;3:6. doi: 10.1186/s40694-016-0024-8. eCollection 2016.

10.

Editorial: 3Rs tightly intertwined to maintain genome stability.

Lisby M, Mortensen UH.

FEMS Yeast Res. 2017 Jan 1;17(1). doi: 10.1093/femsyr/fox003. No abstract available.

PMID:
28073930
11.

High-resolution kinetics and modeling of hydrogen peroxide degradation in live cells.

Altıntaş A, Davidsen K, Garde C, Mortensen UH, Brasen JC, Sams T, Workman CT.

Free Radic Biol Med. 2016 Dec;101:143-153. doi: 10.1016/j.freeradbiomed.2016.10.006. Epub 2016 Oct 11.

PMID:
27742413
12.

Functional Reconstitution of a Fungal Natural Product Gene Cluster by Advanced Genome Editing.

Weber J, Valiante V, Nødvig CS, Mattern DJ, Slotkowski RA, Mortensen UH, Brakhage AA.

ACS Synth Biol. 2017 Jan 20;6(1):62-68. doi: 10.1021/acssynbio.6b00203. Epub 2016 Sep 13.

PMID:
27611015
13.

SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination.

Silva S, Altmannova V, Eckert-Boulet N, Kolesar P, Gallina I, Hang L, Chung I, Arneric M, Zhao X, Buron LD, Mortensen UH, Krejci L, Lisby M.

DNA Repair (Amst). 2016 Jun;42:11-25. doi: 10.1016/j.dnarep.2016.04.001. Epub 2016 Apr 16.

14.

Quantification of oxidative stress phenotypes based on high-throughput growth profiling of protein kinase and phosphatase knockouts.

Altıntaş A, Martini J, Mortensen UH, Workman CT.

FEMS Yeast Res. 2016 Feb;16(1):fov101. doi: 10.1093/femsyr/fov101. Epub 2015 Nov 11.

PMID:
26564984
15.

Investigation of a 6-MSA Synthase Gene Cluster in Aspergillus aculeatus Reveals 6-MSA-derived Aculinic Acid, Aculins A-B and Epi-Aculin A.

Petersen LM, Holm DK, Gotfredsen CH, Mortensen UH, Larsen TO.

Chembiochem. 2015 Oct 12;16(15):2200-4. doi: 10.1002/cbic.201500210. Epub 2015 Sep 16.

PMID:
26374386
16.

A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi.

Nødvig CS, Nielsen JB, Kogle ME, Mortensen UH.

PLoS One. 2015 Jul 15;10(7):e0133085. doi: 10.1371/journal.pone.0133085. eCollection 2015.

17.

Characterization of four new antifungal yanuthones from Aspergillus niger.

Petersen LM, Holm DK, Knudsen PB, Nielsen KF, Gotfredsen CH, Mortensen UH, Larsen TO.

J Antibiot (Tokyo). 2015 Mar;68(3):201-5. doi: 10.1038/ja.2014.130. Epub 2014 Oct 8.

PMID:
25293978
18.

Molecular and chemical characterization of the biosynthesis of the 6-MSA-derived meroterpenoid yanuthone D in Aspergillus niger.

Holm DK, Petersen LM, Klitgaard A, Knudsen PB, Jarczynska ZD, Nielsen KF, Gotfredsen CH, Larsen TO, Mortensen UH.

Chem Biol. 2014 Apr 24;21(4):519-529. doi: 10.1016/j.chembiol.2014.01.013. Epub 2014 Mar 27.

19.

A novel platform for heterologous gene expression in Trichoderma reesei (Teleomorph Hypocrea jecorina).

Jørgensen MS, Skovlund DA, Johannesen PF, Mortensen UH.

Microb Cell Fact. 2014 Mar 6;13(1):33. doi: 10.1186/1475-2859-13-33.

20.

USER-derived cloning methods and their primer design.

Salomonsen B, Mortensen UH, Halkier BA.

Methods Mol Biol. 2014;1116:59-72. doi: 10.1007/978-1-62703-764-8_5.

PMID:
24395357

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