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Items: 1 to 20 of 73


At the Crossing of ER Stress and MAMs: A Key Role of Sigma-1 Receptor?

Delprat B, Crouzier L, Su TP, Maurice T.

Adv Exp Med Biol. 2020;1131:699-718. doi: 10.1007/978-3-030-12457-1_28. Review.


Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion.

Nakamura Y, Dryanovski DI, Kimura Y, Jackson SN, Woods AS, Yasui Y, Tsai SY, Patel S, Covey DP, Su TP, Lupica CR.

Elife. 2019 Oct 9;8. pii: e47209. doi: 10.7554/eLife.47209.


Non-canonical Targets Mediating the Action of Drugs of Abuse: Cocaine at the Sigma-1 Receptor as an Example.

Su TP.

Front Neurosci. 2019 Jul 23;13:761. doi: 10.3389/fnins.2019.00761. eCollection 2019.


Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis.

Hung CY, Hsu TI, Chuang JY, Su TP, Chang WC, Hung JJ.

Mol Neurobiol. 2020 Jan;57(1):261-277. doi: 10.1007/s12035-019-01694-7. Epub 2019 Jul 18.


Genetic deletion of vesicular glutamate transporter in dopamine neurons increases vulnerability to MPTP-induced neurotoxicity in mice.

Shen H, Marino RAM, McDevitt RA, Bi GH, Chen K, Madeo G, Lee PT, Liang Y, De Biase LM, Su TP, Xi ZX, Bonci A.

Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11532-E11541. doi: 10.1073/pnas.1800886115. Epub 2018 Nov 15.


Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress.

Wu CC, Lee PT, Kao TJ, Chou SY, Su RY, Lee YC, Yeh SH, Liou JP, Hsu TI, Su TP, Chuang CK, Chang WC, Chuang JY.

Redox Biol. 2018 Oct;19:74-80. doi: 10.1016/j.redox.2018.08.001. Epub 2018 Aug 4.


Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases.

Weng TY, Tsai SA, Su TP.

J Biomed Sci. 2017 Sep 16;24(1):74. doi: 10.1186/s12929-017-0380-6. Review.


Loss of Sigma-1 Receptor Chaperone Promotes Astrocytosis and Enhances the Nrf2 Antioxidant Defense.

Weng TY, Hung DT, Su TP, Tsai SA.

Oxid Med Cell Longev. 2017;2017:4582135. doi: 10.1155/2017/4582135. Epub 2017 Aug 14.


The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats.

Hong WC, Yano H, Hiranita T, Chin FT, McCurdy CR, Su TP, Amara SG, Katz JL.

J Biol Chem. 2017 Jul 7;292(27):11250-11261. doi: 10.1074/jbc.M116.774075. Epub 2017 May 11.


Sigma-1 Receptors Fine-Tune the Neuronal Networks.

Tsai SA, Su TP.

Adv Exp Med Biol. 2017;964:79-83. doi: 10.1007/978-3-319-50174-1_7. Review.


Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury.

Chuang JY, Kao TJ, Lin SH, Wu AC, Lee PT, Su TP, Yeh SH, Lee YC, Wu CC, Chang WC.

Redox Biol. 2017 Apr;11:135-143. doi: 10.1016/j.redox.2016.11.012. Epub 2016 Nov 29.


The non-apoptotic action of Bcl-xL: regulating Ca(2+) signaling and bioenergetics at the ER-mitochondrion interface.

Williams A, Hayashi T, Wolozny D, Yin B, Su TC, Betenbaugh MJ, Su TP.

J Bioenerg Biomembr. 2016 Jun;48(3):211-25. doi: 10.1007/s10863-016-9664-x. Epub 2016 May 7.


Myristic acid hitchhiking on sigma-1 receptor to fend off neurodegeneration.

Ciesielski J, Su TP, Tsai SY.

Receptors Clin Investig. 2016;3(1). pii: e1114.


The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems.

Su TP, Su TC, Nakamura Y, Tsai SY.

Trends Pharmacol Sci. 2016 Apr;37(4):262-278. doi: 10.1016/ Epub 2016 Feb 9. Review.


The sigma-1 receptor-zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury.

Su TC, Lin SH, Lee PT, Yeh SH, Hsieh TH, Chou SY, Su TP, Hung JJ, Chang WC, Lee YC, Chuang JY.

Neuropharmacology. 2016 Jun;105:1-9. doi: 10.1016/j.neuropharm.2016.01.015. Epub 2016 Jan 11.


A role for sigma receptors in stimulant self-administration and addiction.

Katz JL, Hong WC, Hiranita T, Su TP.

Behav Pharmacol. 2016 Apr;27(2-3 Spec Issue):100-15. doi: 10.1097/FBP.0000000000000209. Review.


Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope.

Tsai SY, Chuang JY, Tsai MS, Wang XF, Xi ZX, Hung JJ, Chang WC, Bonci A, Su TP.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6562-70. doi: 10.1073/pnas.1518894112. Epub 2015 Nov 9.


Detection of Isolated Mitochondria-Associated ER Membranes Using the Sigma-1 Receptor.

Lewis A, Tsai SY, Su TP.

Methods Mol Biol. 2016;1376:133-40. doi: 10.1007/978-1-4939-3170-5_11.


Sigma-1 receptor regulates Tau phosphorylation and axon extension by shaping p35 turnover via myristic acid.

Tsai SY, Pokrass MJ, Klauer NR, Nohara H, Su TP.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6742-7. doi: 10.1073/pnas.1422001112. Epub 2015 May 11.

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