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Items: 1 to 20 of 32

1.

Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure.

Homma T, Kurahashi T, Lee J, Nabeshima A, Yamada S, Fujii J.

Oxid Med Cell Longev. 2018 Jun 27;2018:2812904. doi: 10.1155/2018/2812904. eCollection 2018.

2.

Decreased reproductive performance in xCT-knockout male mice.

Hamashima S, Homma T, Kobayashi S, Ishii N, Kurahashi T, Watanabe R, Kimura N, Sato H, Fujii J.

Free Radic Res. 2017 Oct;51(9-10):851-860. doi: 10.1080/10715762.2017.1388504.

PMID:
28974116
3.

Protective role of testis-specific peroxiredoxin 4 against cellular oxidative stress.

Tasaki E, Matsumoto S, Tada H, Kurahashi T, Zhang X, Fujii J, Utsumi T, Iuchi Y.

J Clin Biochem Nutr. 2017 May;60(3):156-161. doi: 10.3164/jcbn.16-96. Epub 2017 May 1.

4.

xCT deficiency aggravates acetaminophen-induced hepatotoxicity under inhibition of the transsulfuration pathway.

Kang ES, Lee J, Homma T, Kurahashi T, Kobayashi S, Nabeshima A, Yamada S, Seo HG, Miyata S, Sato H, Fujii J.

Free Radic Res. 2017 Jan;51(1):80-90. doi: 10.1080/10715762.2017.1282157.

PMID:
28081640
5.

A high-fat diet temporarily renders Sod1-deficient mice resistant to an oxidative insult.

Ito J, Ishii N, Akihara R, Lee J, Kurahashi T, Homma T, Kawasaki R, Fujii J.

J Nutr Biochem. 2017 Feb;40:44-52. doi: 10.1016/j.jnutbio.2016.10.018. Epub 2016 Nov 3.

PMID:
27855316
6.

Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis.

Shirato T, Homma T, Lee J, Kurahashi T, Fujii J.

Arch Toxicol. 2017 Mar;91(3):1319-1333. doi: 10.1007/s00204-016-1785-9. Epub 2016 Jun 27.

PMID:
27349771
7.

Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy.

Kurahashi T, Lee J, Nabeshima A, Homma T, Kang ES, Saito Y, Yamada S, Nakayama T, Yamada K, Miyata S, Fujii J.

Arch Biochem Biophys. 2016 Aug 15;604:36-46. doi: 10.1016/j.abb.2016.06.004. Epub 2016 Jun 7.

PMID:
27288086
8.

Trichloroethylene exposure aggravates behavioral abnormalities in mice that are deficient in superoxide dismutase.

Otsuki N, Homma T, Fujiwara H, Kaneko K, Hozumi Y, Shichiri M, Takashima M, Ito J, Konno T, Kurahashi T, Yoshida Y, Goto K, Fujii S, Fujii J.

Regul Toxicol Pharmacol. 2016 Aug;79:83-90. doi: 10.1016/j.yrtph.2016.05.007. Epub 2016 May 7.

PMID:
27166294
9.

The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice.

Otsuki N, Konno T, Kurahashi T, Suzuki S, Lee J, Okada F, Iuchi Y, Homma T, Fujii J.

Free Radic Res. 2016 Jul;50(7):793-800. doi: 10.1080/10715762.2016.1178388. Epub 2016 May 5.

PMID:
27080108
10.

Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease.

Nawata A, Noguchi H, Mazaki Y, Kurahashi T, Izumi H, Wang KY, Guo X, Uramoto H, Kohno K, Taniguchi H, Tanaka Y, Fujii J, Sasaguri Y, Tanimoto A, Nakayama T, Yamada S.

PLoS One. 2016 Apr 1;11(4):e0152549. doi: 10.1371/journal.pone.0152549. eCollection 2016.

11.

An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy.

Kurahashi T, Hamashima S, Shirato T, Lee J, Homma T, Kang ES, Fujii J.

Biochem Biophys Res Commun. 2015 Nov 27;467(4):866-71. doi: 10.1016/j.bbrc.2015.10.052. Epub 2015 Oct 19.

PMID:
26474701
12.

SOD1 deficiency decreases proteasomal function, leading to the accumulation of ubiquitinated proteins in erythrocytes.

Homma T, Kurahashi T, Lee J, Kang ES, Fujii J.

Arch Biochem Biophys. 2015 Oct 1;583:65-72. doi: 10.1016/j.abb.2015.07.023. Epub 2015 Aug 8.

PMID:
26264915
13.

Oxidative stress triggers lipid droplet accumulation in primary cultured hepatocytes by activating fatty acid synthesis.

Lee J, Homma T, Kurahashi T, Kang ES, Fujii J.

Biochem Biophys Res Commun. 2015 Aug 14;464(1):229-35. doi: 10.1016/j.bbrc.2015.06.121. Epub 2015 Jun 23.

PMID:
26116535
14.

SOD1 deficiency induces the systemic hyperoxidation of peroxiredoxin in the mouse.

Homma T, Okano S, Lee J, Ito J, Otsuki N, Kurahashi T, Kang ES, Nakajima O, Fujii J.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):1040-6. doi: 10.1016/j.bbrc.2015.06.055. Epub 2015 Jun 12.

PMID:
26079888
15.

Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus.

Fujii J, Kurahashi T, Konno T, Homma T, Iuchi Y.

World J Nephrol. 2015 May 6;4(2):213-22. doi: 10.5527/wjn.v4.i2.213. Review.

16.

Physiological and pathological views of peroxiredoxin 4.

Fujii J, Ikeda Y, Kurahashi T, Homma T.

Free Radic Biol Med. 2015 Jun;83:373-9. doi: 10.1016/j.freeradbiomed.2015.01.025. Epub 2015 Feb 2. Review.

PMID:
25656995
17.

Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals.

Kurahashi T, Kwon M, Homma T, Saito Y, Lee J, Takahashi M, Yamada K, Miyata S, Fujii J.

Biochem Biophys Res Commun. 2014 Sep 12;452(1):136-41. doi: 10.1016/j.bbrc.2014.08.072. Epub 2014 Aug 21.

PMID:
25152401
18.

Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice.

Ito J, Otsuki N, Zhang X, Konno T, Kurahashi T, Takahashi M, Yamato M, Matsuoka Y, Yamada K, Miyata S, Fujii J.

Life Sci. 2014 Jan 24;95(1):1-8. doi: 10.1016/j.lfs.2013.12.004. Epub 2013 Dec 17.

PMID:
24355294
19.

Reactive oxygen species exacerbate autoimmune hemolytic anemia in New Zealand Black mice.

Konno T, Otsuki N, Kurahashi T, Kibe N, Tsunoda S, Iuchi Y, Fujii J.

Free Radic Biol Med. 2013 Dec;65:1378-1384. doi: 10.1016/j.freeradbiomed.2013.09.021. Epub 2013 Oct 2.

PMID:
24095725
20.

Differential responses of SOD1-deficient mouse embryonic fibroblasts to oxygen concentrations.

Tsunoda S, Kibe N, Kurahashi T, Fujii J.

Arch Biochem Biophys. 2013 Sep 1;537(1):5-11. doi: 10.1016/j.abb.2013.06.008. Epub 2013 Jun 27.

PMID:
23811199

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