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Textbooks and other publications on controlled clinical trials, 1948 to 1983.

Johnson T.

J R Soc Med. 2019 Oct;112(10):438-441. doi: 10.1177/0141076819878968. No abstract available.


Tricyclic Indazoles-A Novel Class of Selective Estrogen Receptor Degrader Antagonists.

Scott JS, Bailey A, Buttar D, Carbajo RJ, Curwen J, Davey PRJ, Davies RDM, Degorce SL, Donald C, Gangl E, Greenwood R, Groombridge SD, Johnson T, Lamont S, Lawson M, Lister A, Morrow CJ, Moss TA, Pink JH, Polanski R.

J Med Chem. 2019 Feb 14;62(3):1593-1608. doi: 10.1021/acs.jmedchem.8b01837. Epub 2019 Jan 30.


Major Greenwood and clinical trials.

Farewell V, Johnson T.

J R Soc Med. 2017 Nov;110(11):452-457. doi: 10.1177/0141076817736028. No abstract available.


Estimating direction in brain-behavior interactions: Proactive and reactive brain states in driving.

Garcia JO, Brooks J, Kerick S, Johnson T, Mullen TR, Vettel JM.

Neuroimage. 2017 Apr 15;150:239-249. doi: 10.1016/j.neuroimage.2017.02.057. Epub 2017 Feb 22.


Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer's disease (the DOMINO-AD trial).

Knapp M, King D, Romeo R, Adams J, Baldwin A, Ballard C, Banerjee S, Barber R, Bentham P, Brown RG, Burns A, Dening T, Findlay D, Holmes C, Johnson T, Jones R, Katona C, Lindesay J, Macharouthu A, McKeith I, McShane R, O'Brien JT, Phillips PPJ, Sheehan B, Howard R.

Int J Geriatr Psychiatry. 2017 Dec;32(12):1205-1216. doi: 10.1002/gps.4583. Epub 2016 Oct 13.


Major Greenwood (1880-1949): the biography.

Farewell V, Johnson T.

Stat Med. 2016 Dec 30;35(30):5533-5535. doi: 10.1002/sim.7126. Epub 2016 Sep 22.


Major Greenwood (1880-1949): a biographical and bibliographical study.

Farewell V, Johnson T.

Stat Med. 2016 Feb 28;35(5):645-70. doi: 10.1002/sim.6772. Epub 2015 Nov 10.


Nursing home placement in the Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO-AD) trial: secondary and post-hoc analyses.

Howard R, McShane R, Lindesay J, Ritchie C, Baldwin A, Barber R, Burns A, Dening T, Findlay D, Holmes C, Jones R, Jones R, McKeith I, Macharouthu A, O'Brien J, Sheehan B, Juszczak E, Katona C, Hills R, Knapp M, Ballard C, Brown RG, Banerjee S, Adams J, Johnson T, Bentham P, Phillips PP.

Lancet Neurol. 2015 Dec;14(12):1171-81. doi: 10.1016/S1474-4422(15)00258-6. Epub 2015 Oct 27.


Major Greenwood's early career and the first departments of medical statistics.

Farewell V, Johnson T.

Stat Med. 2014 Jun 15;33(13):2161-77. doi: 10.1002/sim.6134. Epub 2014 Mar 13.


Cost-effectiveness analysis of preoperative transfusion in patients with sickle cell disease using evidence from the TAPS trial.

Spackman E, Sculpher M, Howard J, Malfroy M, Llewelyn C, Choo L, Hodge R, Johnson T, Rees DC, Fijnvandraat K, Kirby-Allen M, Davies S, Williamson L.

Eur J Haematol. 2014 Mar;92(3):249-55. doi: 10.1111/ejh.12232. Epub 2013 Dec 12.


Summary of: Knowledge of removable partial denture wearers on denture hygiene.

Johnson T.

Br Dent J. 2013 Nov;215(10):516-7. doi: 10.1038/sj.bdj.2013.1118. No abstract available.


Influence of personality on the outcome of treatment in depression: systematic review and meta-analysis.

Newton-Howes G, Tyrer P, Johnson T, Mulder R, Kool S, Dekker J, Schoevers R.

J Pers Disord. 2014 Aug;28(4):577-93. doi: 10.1521/pedi_2013_27_070. Epub 2013 Nov 20. Review.


Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2.

Zak M, Hurley CA, Ward SI, Bergeron P, Barrett K, Balazs M, Blair WS, Bull R, Chakravarty P, Chang C, Crackett P, Deshmukh G, DeVoss J, Dragovich PS, Eigenbrot C, Ellwood C, Gaines S, Ghilardi N, Gibbons P, Gradl S, Gribling P, Hamman C, Harstad E, Hewitt P, Johnson A, Johnson T, Kenny JR, Koehler MF, Bir Kohli P, Labadie S, Lee WP, Liao J, Liimatta M, Mendonca R, Narukulla R, Pulk R, Reeve A, Savage S, Shia S, Steffek M, Ubhayakar S, van Abbema A, Aliagas I, Avitabile-Woo B, Xiao Y, Yang J, Kulagowski JJ.

J Med Chem. 2013 Jun 13;56(11):4764-85. doi: 10.1021/jm4004895. Epub 2013 May 31.


Novel triazolo-pyrrolopyridines as inhibitors of Janus kinase 1.

Hurley CA, Blair WS, Bull RJ, Chang C, Crackett PH, Deshmukh G, Dyke HJ, Fong R, Ghilardi N, Gibbons P, Hewitt PR, Johnson A, Johnson T, Kenny JR, Kohli PB, Kulagowski JJ, Liimatta M, Lupardus PJ, Maxey RJ, Mendonca R, Narukulla R, Pulk R, Ubhayakar S, van Abbema A, Ward SI, Waszkowycz B, Zak M.

Bioorg Med Chem Lett. 2013 Jun 15;23(12):3592-8. doi: 10.1016/j.bmcl.2013.04.018. Epub 2013 Apr 17.


The Transfusion Alternatives Preoperatively in Sickle Cell Disease (TAPS) study: a randomised, controlled, multicentre clinical trial.

Howard J, Malfroy M, Llewelyn C, Choo L, Hodge R, Johnson T, Purohit S, Rees DC, Tillyer L, Walker I, Fijnvandraat K, Kirby-Allen M, Spackman E, Davies SC, Williamson LM.

Lancet. 2013 Mar 16;381(9870):930-8. doi: 10.1016/S0140-6736(12)61726-7. Epub 2013 Jan 23.


Vasorelaxing effects and inhibition of nitric oxide in macrophages by new iron-containing carbon monoxide-releasing molecules (CO-RMs).

Motterlini R, Sawle P, Hammad J, Mann BE, Johnson TR, Green CJ, Foresti R.

Pharmacol Res. 2013 Feb;68(1):108-17. doi: 10.1016/j.phrs.2012.12.001. Epub 2012 Dec 17.


Hilda Mary Woods MBE, DSc, LRAM, FSS (1892-1971): reflections on a Fellow of the Royal Statistical Society.

Farewell V, Johnson T, Gear R.

J R Stat Soc Ser A Stat Soc. 2012 Jul;175(3):799-811.


Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2.

Zak M, Mendonca R, Balazs M, Barrett K, Bergeron P, Blair WS, Chang C, Deshmukh G, Devoss J, Dragovich PS, Eigenbrot C, Ghilardi N, Gibbons P, Gradl S, Hamman C, Hanan EJ, Harstad E, Hewitt PR, Hurley CA, Jin T, Johnson A, Johnson T, Kenny JR, Koehler MF, Bir Kohli P, Kulagowski JJ, Labadie S, Liao J, Liimatta M, Lin Z, Lupardus PJ, Maxey RJ, Murray JM, Pulk R, Rodriguez M, Savage S, Shia S, Steffek M, Ubhayakar S, Ultsch M, van Abbema A, Ward SI, Xiao L, Xiao Y.

J Med Chem. 2012 Jul 12;55(13):6176-93. doi: 10.1021/jm300628c. Epub 2012 Jun 28.


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