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Items: 1 to 20 of 202


Dual strands of the miR-223 duplex (miR-223-5p and miR-223-3p) inhibit cancer cell aggressiveness: targeted genes are involved in bladder cancer pathogenesis.

Sugawara S, Yamada Y, Arai T, Okato A, Idichi T, Kato M, Koshizuka K, Ichikawa T, Seki N.

J Hum Genet. 2018 Mar 14. doi: 10.1038/s10038-018-0437-8. [Epub ahead of print]


Molecular pathogenesis of interstitial cystitis based on microRNA expression signature: miR-320 family-regulated molecular pathways and targets.

Arai T, Fuse M, Goto Y, Kaga K, Kurozumi A, Yamada Y, Sugawara S, Okato A, Ichikawa T, Yamanishi T, Seki N.

J Hum Genet. 2018 Mar 12. doi: 10.1038/s10038-018-0419-x. [Epub ahead of print]


Cross-species comparison of the metabolism and excretion of selexipag.

Ichikawa T, Yamada T, Treiber A, Gnerre C, Segrestaa J, Seeland S, Nonaka K.

Xenobiotica. 2018 Feb 22:1-34. doi: 10.1080/00498254.2018.1444814. [Epub ahead of print]


Impact of novel oncogenic pathways regulated by antitumor miR-451a in renal cell carcinoma.

Yamada Y, Arai T, Sugawara S, Okato A, Kato M, Kojima S, Yamazaki K, Naya Y, Ichikawa T, Seki N.

Cancer Sci. 2018 Feb 8. doi: 10.1111/cas.13526. [Epub ahead of print]


Duration of androgen deprivation therapy and nadir of testosterone at 20 ng/dL predict testosterone recovery to supracastrate level in prostate cancer patients who received external beam radiotherapy.

Takei A, Sakamoto S, Wakai K, Tamura T, Imamura Y, Xu M, Maimaiti M, Kawamura K, Imamoto T, Komiya A, Akakura K, Ichikawa T.

Int J Urol. 2018 Jan 11. doi: 10.1111/iju.13521. [Epub ahead of print]


Regulation of HMGB3 by antitumor miR-205-5p inhibits cancer cell aggressiveness and is involved in prostate cancer pathogenesis.

Yamada Y, Nishikawa R, Kato M, Okato A, Arai T, Kojima S, Yamazaki K, Naya Y, Ichikawa T, Seki N.

J Hum Genet. 2018 Feb;63(2):195-205. doi: 10.1038/s10038-017-0371-1. Epub 2017 Dec 1.


Allosteric activation of cytochrome P450 3A4 by efavirenz facilitates midazolam binding.

Ichikawa T, Tsujino H, Miki T, Kobayashi M, Matsubara C, Miyata S, Yamashita T, Takeshita K, Yonezawa Y, Uno T.

Xenobiotica. 2017 Dec 18:1-10. doi: 10.1080/00498254.2017.1412540. [Epub ahead of print]


Significant prognostic difference between Grade Group 4 and 5 in the 2014 International Society of Urological Pathology Grading System for High Grade Prostate Cancer with Bone Metastasis.

Yamada Y, Sakamoto S, Shimazaki J, Sugiura M, Amiya Y, Sasaki M, Shima T, Komiya A, Suzuki N, Akakura K, Ichikawa T, Nakatsu H.

Prostate Int. 2017 Dec;5(4):143-148. doi: 10.1016/j.prnil.2017.03.001. Epub 2017 Mar 16.


Cancer-specific mortality of high-risk prostate cancer after carbon-ion radiotherapy plus long-term androgen deprivation therapy.

Kasuya G, Ishikawa H, Tsuji H, Haruyama Y, Kobashi G, Ebner DK, Akakura K, Suzuki H, Ichikawa T, Shimazaki J, Makishima H, Nomiya T, Kamada T, Tsujii H; Working Group for Genitourinary Tumors.

Cancer Sci. 2017 Dec;108(12):2422-2429. doi: 10.1111/cas.13402. Epub 2017 Nov 3.


Dual Strands of Pre-miR-149 Inhibit Cancer Cell Migration and Invasion through Targeting FOXM1 in Renal Cell Carcinoma.

Okato A, Arai T, Yamada Y, Sugawara S, Koshizuka K, Fujimura L, Kurozumi A, Kato M, Kojima S, Naya Y, Ichikawa T, Seki N.

Int J Mol Sci. 2017 Sep 13;18(9). pii: E1969. doi: 10.3390/ijms18091969.


Testosterone Reduction of ≥ 480 ng/dL Predicts Favorable Prognosis of Japanese Men With Advanced Prostate Cancer Treated With Androgen-Deprivation Therapy.

Yamamoto S, Sakamoto S, Minhui X, Tamura T, Otsuka K, Sato K, Maimaiti M, Kamada S, Takei A, Fuse M, Kawamura K, Imamoto T, Komiya A, Akakura K, Ichikawa T.

Clin Genitourin Cancer. 2017 Dec;15(6):e1107-e1115. doi: 10.1016/j.clgc.2017.07.023. Epub 2017 Aug 3.


Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma.

Arai T, Okato A, Kojima S, Idichi T, Koshizuka K, Kurozumi A, Kato M, Yamazaki K, Ishida Y, Naya Y, Ichikawa T, Seki N.

Cancer Sci. 2017 Oct;108(10):2088-2101. doi: 10.1111/cas.13331. Epub 2017 Aug 19.


The metabolism and drug-drug interaction potential of the selective prostacyclin receptor agonist selexipag.

Gnerre C, Segrestaa J, Seeland S, Äänismaa P, Pfeifer T, Delahaye S, de Kanter R, Ichikawa T, Yamada T, Treiber A.

Xenobiotica. 2017 Aug 30:1-16. doi: 10.1080/00498254.2017.1357088. [Epub ahead of print]


Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer.

Goto Y, Kurozumi A, Arai T, Nohata N, Kojima S, Okato A, Kato M, Yamazaki K, Ishida Y, Naya Y, Ichikawa T, Seki N.

Br J Cancer. 2017 Jul 25;117(3):409-420. doi: 10.1038/bjc.2017.191. Epub 2017 Jun 22.


Expression profile of urothelial transcription factors in bladder biopsies with interstitial cystitis.

Kaga K, Inoue KI, Kaga M, Ichikawa T, Yamanishi T.

Int J Urol. 2017 Aug;24(8):632-638. doi: 10.1111/iju.13391. Epub 2017 Jun 18.


Dual strands of pre-miR‑150 (miR‑150‑5p and miR‑150‑3p) act as antitumor miRNAs targeting SPOCK1 in naïve and castration-resistant prostate cancer.

Okato A, Arai T, Kojima S, Koshizuka K, Osako Y, Idichi T, Kurozumi A, Goto Y, Kato M, Naya Y, Ichikawa T, Seki N.

Int J Oncol. 2017 Jul;51(1):245-256. doi: 10.3892/ijo.2017.4008. Epub 2017 May 17.


Role of lymph node dissection during radical nephroureterectomy for upper urinary tract urothelial cancer: multi-institutional large retrospective study JCOG1110A.

Inokuchi J, Kuroiwa K, Kakehi Y, Sugimoto M, Tanigawa T, Fujimoto H, Gotoh M, Masumori N, Ogawa O, Eto M, Ohyama C, Yamaguchi A, Matsuyama H, Ichikawa T, Asano T, Mizusawa J, Eba J, Naito S.

World J Urol. 2017 Nov;35(11):1737-1744. doi: 10.1007/s00345-017-2049-x. Epub 2017 May 15.


Development of novel nomograms to predict renal functional outcomes after laparoscopic adrenalectomy in patients with primary aldosteronism.

Utsumi T, Kamiya N, Kaga M, Endo T, Yano M, Kamijima S, Kawamura K, Imamoto T, Ichikawa T, Suzuki H.

World J Urol. 2017 Oct;35(10):1577-1583. doi: 10.1007/s00345-017-2033-5. Epub 2017 Apr 11.


Pharmacokinetics of the selective prostacyclin receptor agonist selexipag in rats, dogs and monkeys.

Ichikawa T, Yamada T, Treiber A, Gnerre C, Nonaka K.

Xenobiotica. 2018 Feb;48(2):186-196. doi: 10.1080/00498254.2017.1294277. Epub 2017 Mar 2.


Hypertension Cure Following Laparoscopic Adrenalectomy for Hyperaldosteronism is not Universal: Trends Over Two Decades.

Namekawa T, Utsumi T, Tanaka T, Kaga M, Nagano H, Kono T, Kawamura K, Kamiya N, Imamoto T, Suzuki H, Ichikawa T.

World J Surg. 2017 Apr;41(4):986-990. doi: 10.1007/s00268-016-3822-5.


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