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Items: 1 to 20 of 55

1.

Corrigendum: Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III.

Ma D, Pignanelli C, Tarade D, Gilbert T, Noel M, Mansour F, Adams S, Dowhayko A, Stokes K, Vshyvenko S, Collins J, Hudlicky T, McNulty J, Pandey S.

Sci Rep. 2018 Jul 4;8:46998. doi: 10.1038/srep46998.

2.

Isolation, Synthesis, and Semisynthesis of Amaryllidaceae Constituents from Narcissus and Galanthus sp.: De Novo Total Synthesis of 2- epi-Narciclasine.

Borra S, Lapinskaite R, Kempthorne C, Liscombe D, McNulty J, Hudlicky T.

J Nat Prod. 2018 Jun 22;81(6):1451-1459. doi: 10.1021/acs.jnatprod.8b00218. Epub 2018 May 22.

PMID:
29787267
3.

Chemoenzymatic Synthesis of Advanced Intermediates for Formal Total Syntheses of Tetrodotoxin.

Baidilov D, Rycek L, Trant JF, Froese J, Murphy B, Hudlicky T.

Angew Chem Int Ed Engl. 2018 Aug 20;57(34):10994-10998. doi: 10.1002/anie.201804602. Epub 2018 May 30.

PMID:
29750851
4.

Rosmarinic Acid, a Rosemary Extract Polyphenol, Increases Skeletal Muscle Cell Glucose Uptake and Activates AMPK.

Vlavcheski F, Naimi M, Murphy B, Hudlicky T, Tsiani E.

Molecules. 2017 Oct 7;22(10). pii: E1669. doi: 10.3390/molecules22101669.

5.

Exploiting mitochondrial and oxidative vulnerabilities with a synthetic analog of pancratistatin in combination with piperlongumine for cancer therapy.

Ma D, Gilbert T, Pignanelli C, Tarade D, Noel M, Mansour F, Gupta M, Ma S, Ropat J, Curran C, Vshyvenko S, Hudlicky T, Pandey S.

FASEB J. 2018 Jan;32(1):417-430. doi: 10.1096/fj.201700275R. Epub 2017 Sep 19.

PMID:
28928246
6.

Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III.

Ma D, Pignanelli C, Tarade D, Gilbert T, Noel M, Mansour F, Adams S, Dowhayko A, Stokes K, Vshyvenko S, Hudlicky T, McNulty J, Pandey S.

Sci Rep. 2017 Feb 21;7:42957. doi: 10.1038/srep42957. Erratum in: Sci Rep. 2018 Jul 04;8:46998.

7.

Applications of the Wittig-Still Rearrangement in Organic Synthesis.

Rycek L, Hudlicky T.

Angew Chem Int Ed Engl. 2017 May 22;56(22):6022-6066. doi: 10.1002/anie.201611329. Epub 2017 Apr 25. Review.

PMID:
28211171
8.

A Formal Approach to Xylosmin and Flacourtosides E and F: Chemoenzymatic Total Synthesis of the Hydroxylated Cyclohexenone Carboxylic Acid Moiety of Xylosmin.

Ghavre M, Froese J, Murphy B, Simionescu R, Hudlicky T.

Org Lett. 2017 Mar 3;19(5):1156-1159. doi: 10.1021/acs.orglett.7b00194. Epub 2017 Feb 10.

PMID:
28186763
9.

Chemoenzymatic Total Synthesis of Hydromorphone by an Oxidative Dearomatization/Intramolecular [4 + 2] Cycloaddition Sequence: A Second-Generation Approach.

Rycek L, Hayward JJ, Latif MA, Tanko J, Simionescu R, Hudlicky T.

J Org Chem. 2016 Nov 18;81(22):10930-10941. Epub 2016 Oct 18.

PMID:
27690149
10.

Carnosic acid as a component of rosemary extract stimulates skeletal muscle cell glucose uptake via AMPK activation.

Naimi M, Vlavcheski F, Murphy B, Hudlicky T, Tsiani E.

Clin Exp Pharmacol Physiol. 2017 Jan;44(1):94-102. doi: 10.1111/1440-1681.12674.

PMID:
27716981
11.

Chemoenzymatic Total Synthesis of (+)-Galanthamine and (+)-Narwedine from Phenethyl Acetate.

Endoma-Arias MA, Hudlicky T.

Chemistry. 2016 Oct 4;22(41):14540-3. doi: 10.1002/chem.201603735. Epub 2016 Aug 26.

PMID:
27505136
12.

Synthesis of Amaryllidaceae Constituents and Unnatural Derivatives.

Ghavre M, Froese J, Pour M, Hudlicky T.

Angew Chem Int Ed Engl. 2016 May 4;55(19):5642-91. doi: 10.1002/anie.201508227. Epub 2016 Mar 11. Review.

PMID:
26969844
13.

Chemoenzymatic Synthesis of Pleiogenone A: An Antiproliferative Trihydroxyalkylcyclohexenone Isolated from Pleiogynium timorense.

Froese J, Overbeeke C, Hudlicky T.

Chemistry. 2016 Apr 25;22(18):6180-4. doi: 10.1002/chem.201601061. Epub 2016 Apr 1.

PMID:
26956129
14.

Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast.

Qu Y, Easson ML, Froese J, Simionescu R, Hudlicky T, De Luca V.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6224-9. doi: 10.1073/pnas.1501821112. Epub 2015 Apr 27.

15.

The quest for a practical synthesis of morphine alkaloids and their derivatives by chemoenzymatic methods.

Reed JW, Hudlicky T.

Acc Chem Res. 2015 Mar 17;48(3):674-87. doi: 10.1021/ar500427k. Epub 2015 Mar 2.

PMID:
25730681
16.
17.

Synthesis and biological evaluation of unnatural derivatives of narciclasine: 7-aza-nornarciclasine and its N-oxide.

Vshyvenko S, Reisenauer MR, Rogelj S, Hudlicky T.

Bioorg Med Chem Lett. 2014 Sep 1;24(17):4236-8. doi: 10.1016/j.bmcl.2014.07.034. Epub 2014 Jul 19.

18.

Short chemoenzymatic total synthesis of ent-hydromorphone: an oxidative dearomatization/intramolecular [4+2] cycloaddition/amination sequence.

Varghese V, Hudlicky T.

Angew Chem Int Ed Engl. 2014 Apr 22;53(17):4355-8. doi: 10.1002/anie.201400286. Epub 2014 Mar 18.

PMID:
24644041
19.

Enantioselective total synthesis and biological evaluation of (+)-kibdelone A and a tetrahydroxanthone analogue.

Winter DK, Endoma-Arias MA, Hudlicky T, Beutler JA, Porco JA Jr.

J Org Chem. 2013 Aug 2;78(15):7617-26. doi: 10.1021/jo401169z. Epub 2013 Jul 23.

20.

Heteroatom analogues of hydrocodone: synthesis and biological activity.

Giacometti RD, Duchek J, Werner L, Husni AS, McCurdy CR, Cutler SJ, Cox DP, Hudlicky T.

J Org Chem. 2013 Apr 5;78(7):2914-25. doi: 10.1021/jo3026753. Epub 2013 Mar 6.

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