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Items: 1 to 20 of 31

1.

Correction to "Display Selection of Exotic Macrocyclic Peptides Expressed Under a Radically Reprogrammed 23 Amino Acid Genetic Code".

Passioura T, Liu W, Dunkelmann D, Higuchi T, Suga H.

J Am Chem Soc. 2019 Jul 24;141(29):11727-11728. doi: 10.1021/jacs.9b06806. Epub 2019 Jul 9. No abstract available.

PMID:
31287675
2.

Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.

Sakai K, Passioura T, Sato H, Ito K, Furuhashi H, Umitsu M, Takagi J, Kato Y, Mukai H, Warashina S, Zouda M, Watanabe Y, Yano S, Shibata M, Suga H, Matsumoto K.

Nat Chem Biol. 2019 Jun;15(6):598-606. doi: 10.1038/s41589-019-0285-7. Epub 2019 May 17.

PMID:
31101918
3.

De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease.

Nitsche C, Passioura T, Varava P, Mahawaththa MC, Leuthold MM, Klein CD, Suga H, Otting G.

ACS Med Chem Lett. 2019 Jan 4;10(2):168-174. doi: 10.1021/acsmedchemlett.8b00535. eCollection 2019 Feb 14.

PMID:
30783498
4.

Ribosomal Synthesis of Backbone-Cyclic Peptides Compatible with In Vitro Display.

Takatsuji R, Shinbara K, Katoh T, Goto Y, Passioura T, Yajima R, Komatsu Y, Suga H.

J Am Chem Soc. 2019 Feb 13;141(6):2279-2287. doi: 10.1021/jacs.8b05327. Epub 2019 Feb 1.

PMID:
30648857
5.

Corrigendum to "Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A" [Bioorg. Med. Chem. 26/6 (2018) 1225-1231].

Passioura T, Bhushan B, Tumber A, Kawamura A, Suga H.

Bioorg Med Chem. 2019 Feb 1;27(3):578. doi: 10.1016/j.bmc.2018.12.020. Epub 2018 Dec 26. No abstract available.

PMID:
30594451
6.

Structural Features and Binding Modes of Thioether-Cyclized Peptide Ligands.

Otero-Ramirez ME, Passioura T, Suga H.

Biomedicines. 2018 Dec 13;6(4). pii: E116. doi: 10.3390/biomedicines6040116. Review.

7.

Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis.

Decoene KW, Vannecke W, Passioura T, Suga H, Madder A.

Biomedicines. 2018 Oct 30;6(4). pii: E99. doi: 10.3390/biomedicines6040099.

8.

Nonproteinogenic deep mutational scanning of linear and cyclic peptides.

Rogers JM, Passioura T, Suga H.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):10959-10964. doi: 10.1073/pnas.1809901115. Epub 2018 Oct 9.

9.

Display Selection of Exotic Macrocyclic Peptides Expressed under a Radically Reprogrammed 23 Amino Acid Genetic Code.

Passioura T, Liu W, Dunkelmann D, Higuchi T, Suga H.

J Am Chem Soc. 2018 Sep 19;140(37):11551-11555. doi: 10.1021/jacs.8b03367. Epub 2018 Sep 4. Erratum in: J Am Chem Soc. 2019 Jul 9;:.

PMID:
30157372
10.

De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry.

Passioura T, Watashi K, Fukano K, Shimura S, Saso W, Morishita R, Ogasawara Y, Tanaka Y, Mizokami M, Sureau C, Suga H, Wakita T.

Cell Chem Biol. 2018 Jul 19;25(7):906-915.e5. doi: 10.1016/j.chembiol.2018.04.011. Epub 2018 May 17.

11.

Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A.

Passioura T, Bhushan B, Tumber A, Kawamura A, Suga H.

Bioorg Med Chem. 2018 Mar 15;26(6):1225-1231. doi: 10.1016/j.bmc.2018.01.013. Epub 2018 Jan 31. Erratum in: Bioorg Med Chem. 2019 Feb 1;27(3):578.

PMID:
29402611
12.

Identification of nonstandard macrocyclic peptide ligands through display screening.

Taylor RD, Rey-Carrizo M, Passioura T, Suga H.

Drug Discov Today Technol. 2017 Dec;26:17-23. doi: 10.1016/j.ddtec.2017.10.005. Epub 2017 Nov 15. Review.

PMID:
29249238
13.

Macrocyclic peptide inhibitors for the protein-protein interaction of Zaire Ebola virus protein 24 and karyopherin alpha 5.

Song X, Lu LY, Passioura T, Suga H.

Org Biomol Chem. 2017 Jun 21;15(24):5155-5160. doi: 10.1039/c7ob00012j.

PMID:
28574091
14.

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.

Kawamura A, Münzel M, Kojima T, Yapp C, Bhushan B, Goto Y, Tumber A, Katoh T, King ON, Passioura T, Walport LJ, Hatch SB, Madden S, Müller S, Brennan PE, Chowdhury R, Hopkinson RJ, Suga H, Schofield CJ.

Nat Commun. 2017 Apr 6;8:14773. doi: 10.1038/ncomms14773.

15.

A RaPID way to discover nonstandard macrocyclic peptide modulators of drug targets.

Passioura T, Suga H.

Chem Commun (Camb). 2017 Feb 7;53(12):1931-1940. doi: 10.1039/c6cc06951g. Review.

PMID:
28091672
16.

Reprogramming the genetic code in vitro.

Passioura T, Suga H.

Trends Biochem Sci. 2014 Sep;39(9):400-8. doi: 10.1016/j.tibs.2014.07.005. Epub 2014 Aug 13. Review.

PMID:
25129886
17.

Selection-based discovery of druglike macrocyclic peptides.

Passioura T, Katoh T, Goto Y, Suga H.

Annu Rev Biochem. 2014;83:727-52. doi: 10.1146/annurev-biochem-060713-035456. Epub 2014 Feb 21. Review.

PMID:
24580641
18.

Flexizyme-mediated genetic reprogramming as a tool for noncanonical peptide synthesis and drug discovery.

Passioura T, Suga H.

Chemistry. 2013 May 17;19(21):6530-6. doi: 10.1002/chem.201300247. Epub 2013 Mar 20.

PMID:
23519693
19.

Technologies for the synthesis of mRNA-encoding libraries and discovery of bioactive natural product-inspired non-traditional macrocyclic peptides.

Ito K, Passioura T, Suga H.

Molecules. 2013 Mar 18;18(3):3502-28. doi: 10.3390/molecules18033502. Review.

20.

Flexizymes, their evolutionary history and diverse utilities.

Passioura T, Suga H.

Top Curr Chem. 2014;344:331-45. doi: 10.1007/128_2013_421. Review.

PMID:
23478876

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