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Items: 19

1.

No light without the dark: Perspectives and hindrances for translation of cardiac optogenetics.

Richter C, Bruegmann T.

Prog Biophys Mol Biol. 2019 Sep 9. pii: S0079-6107(19)30114-2. doi: 10.1016/j.pbiomolbio.2019.08.013. [Epub ahead of print] Review.

PMID:
31515056
2.

Evaluating the Efficiency of gRNAs in CRISPR/Cas9 Mediated Genome Editing in Poplars.

Bruegmann T, Deecke K, Fladung M.

Int J Mol Sci. 2019 Jul 24;20(15). pii: E3623. doi: 10.3390/ijms20153623.

3.

Optogenetic Termination of Cardiac Arrhythmia: Mechanistic Enlightenment and Therapeutic Application?

Sasse P, Funken M, Beiert T, Bruegmann T.

Front Physiol. 2019 Jun 6;10:675. doi: 10.3389/fphys.2019.00675. eCollection 2019. Review.

4.

Optogenetic Hyperpolarization of Cardiomyocytes Terminates Ventricular Arrhythmia.

Funken M, Malan D, Sasse P, Bruegmann T.

Front Physiol. 2019 Apr 24;10:498. doi: 10.3389/fphys.2019.00498. eCollection 2019.

5.

Optogenetic stimulation of Gs-signaling in the heart with high spatio-temporal precision.

Makowka P, Bruegmann T, Dusend V, Malan D, Beiert T, Hesse M, Fleischmann BK, Sasse P.

Nat Commun. 2019 Mar 20;10(1):1281. doi: 10.1038/s41467-019-09322-7.

6.

Poplar Transformation.

Bruegmann T, Polak O, Deecke K, Nietsch J, Fladung M.

Methods Mol Biol. 2019;1864:165-177. doi: 10.1007/978-1-4939-8778-8_12.

PMID:
30415336
7.

Knockdown of PCBER1, a gene of neolignan biosynthesis, resulted in increased poplar growth.

Bruegmann T, Wetzel H, Hettrich K, Smeds A, Willför S, Kersten B, Fladung M.

Planta. 2019 Feb;249(2):515-525. doi: 10.1007/s00425-018-3021-8. Epub 2018 Sep 29.

PMID:
30269193
8.

Optical control of L-type Ca2+ channels using a diltiazem photoswitch.

Fehrentz T, Huber FME, Hartrampf N, Bruegmann T, Frank JA, Fine NHF, Malan D, Danzl JG, Tikhonov DB, Sumser M, Sasse P, Hodson DJ, Zhorov BS, Klöcker N, Trauner D.

Nat Chem Biol. 2018 Aug;14(8):764-767. doi: 10.1038/s41589-018-0090-8. Epub 2018 Jul 16.

PMID:
30013061
9.

Macrophages: new players in cardiac ageing?

Bruegmann T, Smith GL.

Cardiovasc Res. 2018 Jun 1;114(7):e47-e49. doi: 10.1093/cvr/cvy047. No abstract available.

PMID:
29800376
10.

Optogenetic termination of atrial fibrillation in mice.

Bruegmann T, Beiert T, Vogt CC, Schrickel JW, Sasse P.

Cardiovasc Res. 2018 Apr 1;114(5):713-723. doi: 10.1093/cvr/cvx250.

PMID:
29293898
11.

Frequency-Dependent Multi-Well Cardiotoxicity Screening Enabled by Optogenetic Stimulation.

Rehnelt S, Malan D, Juhasz K, Wolters B, Doerr L, Beckler M, Kettenhofen R, Bohlen H, Bruegmann T, Sasse P.

Int J Mol Sci. 2017 Dec 6;18(12). pii: E2634. doi: 10.3390/ijms18122634.

12.

Spot light on skeletal muscles: optogenetic stimulation to understand and restore skeletal muscle function.

van Bremen T, Send T, Sasse P, Bruegmann T.

J Muscle Res Cell Motil. 2017 Aug;38(3-4):331-337. doi: 10.1007/s10974-017-9481-9. Epub 2017 Sep 16.

PMID:
28918572
13.

Frequency-dependent drug screening using optogenetic stimulation of human iPSC-derived cardiomyocytes.

Lapp H, Bruegmann T, Malan D, Friedrichs S, Kilgus C, Heidsieck A, Sasse P.

Sci Rep. 2017 Aug 29;7(1):9629. doi: 10.1038/s41598-017-09760-7.

14.

Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations.

Bruegmann T, Boyle PM, Vogt CC, Karathanos TV, Arevalo HJ, Fleischmann BK, Trayanova NA, Sasse P.

J Clin Invest. 2016 Oct 3;126(10):3894-3904. doi: 10.1172/JCI88950. Epub 2016 Sep 12.

15.

Optogenetic control of contractile function in skeletal muscle.

Bruegmann T, van Bremen T, Vogt CC, Send T, Fleischmann BK, Sasse P.

Nat Commun. 2015 Jun 2;6:7153. doi: 10.1038/ncomms8153.

16.

Systemic gene transfer enables optogenetic pacing of mouse hearts.

Vogt CC, Bruegmann T, Malan D, Ottersbach A, Roell W, Fleischmann BK, Sasse P.

Cardiovasc Res. 2015 May 1;106(2):338-43. doi: 10.1093/cvr/cvv004. Epub 2015 Jan 12.

PMID:
25587047
17.

Optogenetic cardiac pacemakers: science or fiction?

Bruegmann T, Sasse P.

Trends Cardiovasc Med. 2015 Feb;25(2):82-3. doi: 10.1016/j.tcm.2014.10.016. Epub 2014 Oct 30. No abstract available.

PMID:
25467240
18.

Optogenetic activation of Gq signalling modulates pacemaker activity of cardiomyocytes.

Beiert T, Bruegmann T, Sasse P.

Cardiovasc Res. 2014 Jun 1;102(3):507-16. doi: 10.1093/cvr/cvu046. Epub 2014 Feb 27.

PMID:
24576953
19.

Optogenetic control of heart muscle in vitro and in vivo.

Bruegmann T, Malan D, Hesse M, Beiert T, Fuegemann CJ, Fleischmann BK, Sasse P.

Nat Methods. 2010 Nov;7(11):897-900. doi: 10.1038/nmeth.1512. Epub 2010 Oct 3.

PMID:
20881965

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