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Items: 1 to 20 of 72

1.

Tavaborole 5% Topical Solution for the Treatment of Toenail Onychomycosis in Pediatric Patients: Results from a Phase 4 Open-Label Study

Rich P, Spellman M, Purohit V, Zang C, Crook TJ.

J Drugs Dermatol. 2019 Feb 1;18(2):190-195.

PMID:
30811142
2.

Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM.

Przystal JM, Hajji N, Khozoie C, Renziehausen A, Zeng Q, Abaitua F, Hajitou A, Suwan K, Want E, Bomalaski J, Szlosarek P, O'Neill K, Crook T, Syed N.

Cell Death Dis. 2018 Dec 13;9(12):1192. doi: 10.1038/s41419-018-1195-4.

3.

The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.

Renziehausen A, Wang H, Rao B, Weir L, Nigro CL, Lattanzio L, Merlano M, Vega-Rioja A, Del Carmen Fernandez-Carranco M, Hajji N, Matin R, Harwood C, Li S, Sim VR, O'Neill K, Evans A, Thompson A, Szlosarek P, Fleming C, Stebbing J, Proby C, Tzakos AG, Syed N, Crook T.

Oncogene. 2019 Mar;38(13):2320-2336. doi: 10.1038/s41388-018-0563-y. Epub 2018 Nov 26.

PMID:
30478450
4.

Development of a validated LC-MS/MS method for the in vitro and in vivo quantitation of sunitinib in glioblastoma cells and cancer patients.

Chatziathanasiadou MV, Stylos EK, Giannopoulou E, Spyridaki MH, Briasoulis E, Kalofonos HP, Crook T, Syed N, Sivolapenko GB, Tzakos AG.

J Pharm Biomed Anal. 2019 Feb 5;164:690-697. doi: 10.1016/j.jpba.2018.11.030. Epub 2018 Nov 14.

PMID:
30472587
5.

Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma.

Atkinson A, Renziehausen A, Wang H, Lo Nigro C, Lattanzio L, Merlano M, Rao B, Weir L, Evans A, Matin R, Harwood C, Szlosarek P, Pickering JG, Fleming C, Sim VR, Li S, Vasta JT, Raines RT, Boniol M, Thompson A, Proby C, Crook T, Syed N.

J Invest Dermatol. 2019 May;139(5):1118-1126. doi: 10.1016/j.jid.2018.10.038. Epub 2018 Nov 16.

PMID:
30452903
6.

Development and validation of simple step protein precipitation UHPLC-MS/MS methods for quantitation of temozolomide in cancer patient plasma samples.

El Mubarak MA, Stylos EK, Chatziathanasiadou MV, Danika C, Alexiou GA, Tsekeris P, Renziehausen A, Crook T, Syed N, Sivolapenko GB, Tzakos AG.

J Pharm Biomed Anal. 2019 Jan 5;162:164-170. doi: 10.1016/j.jpba.2018.09.019. Epub 2018 Sep 8.

PMID:
30243056
7.

DUSP2 methylation is a candidate biomarker of outcome in head and neck cancer.

Lo Nigro C, Vivenza D, Denaro N, Lattanzio L, Fortunato M, Crook T, Merlano MC.

Ann Transl Med. 2018 Jul;6(13):271. doi: 10.21037/atm.2018.06.39.

8.

Correction to: Metabolomic profiling identifies distinct phenotypes for ASS1 positive and negative GBM.

Mörén L, Perryman R, Crook T, Langer JK, Oneill K, Syed N, Antti H.

BMC Cancer. 2018 Mar 8;18(1):268. doi: 10.1186/s12885-018-4128-9.

9.

Metabolomic profiling identifies distinct phenotypes for ASS1 positive and negative GBM.

Mörén L, Perryman R, Crook T, Langer JK, Oneill K, Syed N, Antti H.

BMC Cancer. 2018 Feb 8;18(1):167. doi: 10.1186/s12885-018-4040-3. Erratum in: BMC Cancer. 2018 Mar 8;18(1):268.

10.

The efficacy and safety of tofacitinib in Asian patients with moderate to severe chronic plaque psoriasis: A Phase 3, randomized, double-blind, placebo-controlled study.

Zhang J, Tsai TF, Lee MG, Zheng M, Wang G, Jin H, Gu J, Li R, Liu Q, Chen J, Tu C, Qi C, Zhu H, Ports WC, Crook T.

J Dermatol Sci. 2017 Oct;88(1):36-45. doi: 10.1016/j.jdermsci.2017.05.004. Epub 2017 May 16.

11.

Tanezumab Reduces Pain in Women with Interstitial Cystitis/Bladder Pain Syndrome and Patients with Nonurological Associated Somatic Syndromes.

Nickel JC, Mills IW, Crook TJ, Jorga A, Smith MD, Atkinson G, Krieger JN.

J Urol. 2016 Apr;195(4 Pt 1):942-8. doi: 10.1016/j.juro.2015.10.178. Epub 2015 Nov 11.

PMID:
26576710
12.

Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control.

Ingemarsdotter CK, Tookman LA, Browne A, Pirlo K, Cutts R, Chelela C, Khurrum KF, Leung EY, Dowson S, Webber L, Khan I, Ennis D, Syed N, Crook TR, Brenton JD, Lockley M, McNeish IA.

Mol Oncol. 2015 Apr;9(4):791-805. doi: 10.1016/j.molonc.2014.12.007. Epub 2014 Dec 29.

13.

A blood test to identify when melanoma metastasizes: a reality for melanoma management?

Hatzimichael E, Syed N, Lo Nigro C, Crook T.

Melanoma Manag. 2014 Aug;1(1):11-14. doi: 10.2217/mmt.14.11. Epub 2014 Sep 5. No abstract available.

14.

How detection of epigenetic alterations of blood-borne DNA could improve melanoma diagnosis.

Hatzimichael E, Syed N, Lo Nigro C, Rao B, Crook T.

Expert Rev Mol Diagn. 2014 Jul;14(6):639-42. doi: 10.1586/14737159.2014.928204. Epub 2014 Jun 13.

PMID:
24926921
15.

Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II.

Magnani F, Pappas CG, Crook T, Magafa V, Cordopatis P, Ishiguro S, Ohta N, Selent J, Bosnyak S, Jones ES, Gerothanassis IP, Tamura M, Widdop RE, Tzakos AG.

ACS Chem Biol. 2014 Jul 18;9(7):1420-5. doi: 10.1021/cb500063y. Epub 2014 May 14.

16.

Epigenetics in diagnosis, prognostic assessment and treatment of cancer: an update.

Hatzimichael E, Lagos K, Sim VR, Briasoulis E, Crook T.

EXCLI J. 2014 Aug 26;13:954-76. eCollection 2014. Review.

17.

Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging.

Allen MD, Luong P, Hudson C, Leyton J, Delage B, Ghazaly E, Cutts R, Yuan M, Syed N, Lo Nigro C, Lattanzio L, Chmielewska-Kassassir M, Tomlinson I, Roylance R, Whitaker HC, Warren AY, Neal D, Frezza C, Beltran L, Jones LJ, Chelala C, Wu BW, Bomalaski JS, Jackson RC, Lu YJ, Crook T, Lemoine NR, Mather S, Foster J, Sosabowski J, Avril N, Li CF, Szlosarek PW.

Cancer Res. 2014 Feb 1;74(3):896-907. doi: 10.1158/0008-5472.CAN-13-1702. Epub 2013 Nov 27.

18.

Cancer epigenetics: new therapies and new challenges.

Hatzimichael E, Crook T.

J Drug Deliv. 2013;2013:529312. doi: 10.1155/2013/529312. Epub 2013 Feb 26.

19.

Methylated tissue factor pathway inhibitor 2 (TFPI2) DNA in serum is a biomarker of metastatic melanoma.

Lo Nigro C, Wang H, McHugh A, Lattanzio L, Matin R, Harwood C, Syed N, Hatzimichael E, Briasoulis E, Merlano M, Evans A, Thompson A, Leigh I, Fleming C, Inman GJ, Proby C, Crook T.

J Invest Dermatol. 2013 May;133(5):1278-85. doi: 10.1038/jid.2012.493. Epub 2013 Feb 14.

20.

Preliminary assessment of safety and efficacy in proof-of-concept, randomized clinical trial of tanezumab for chronic prostatitis/chronic pelvic pain syndrome.

Nickel JC, Atkinson G, Krieger JN, Mills IW, Pontari M, Shoskes DA, Crook TJ.

Urology. 2012 Nov;80(5):1105-10. doi: 10.1016/j.urology.2012.07.035. Epub 2012 Sep 23.

PMID:
23010344

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