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Items: 1 to 20 of 156


Evaluating the Bioactivity of a Novel Antimicrobial and Anticancer Peptide, Dermaseptin-PS4(Der-PS4), from the Skin Secretion of Phyllomedusa sauvagii.

Chen D, Zhou X, Chen X, Huang L, Xi X, Ma C, Zhou M, Wang L, Chen T.

Molecules. 2019 Aug 16;24(16). pii: E2974. doi: 10.3390/molecules24162974.


Boiling Licorice Produces Self-Assembled Protein Nanoparticles: A Novel Source of Bioactive Nanomaterials.

Zhou J, Zhang J, Gao G, Wang H, He X, Chen T, Ke L, Rao P, Wang Q.

J Agric Food Chem. 2019 Aug 8. doi: 10.1021/acs.jafc.9b03208. [Epub ahead of print]


Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor.

Miao Y, Chen G, Xi X, Ma C, Wang L, Burrows JF, Duan J, Zhou M, Chen T.

Biomolecules. 2019 Jul 14;9(7). pii: E280. doi: 10.3390/biom9070280.


A Novel Kunitzin-Like Trypsin Inhibitor Isolated from Defensive Skin Secretion of Odorrana versabilis.

Dong Y, Shi D, Ying Y, Xi X, Chen X, Wang L, Zhou M, Wu Q, Ma C, Chen T.

Biomolecules. 2019 Jun 28;9(7). pii: E254. doi: 10.3390/biom9070254.


A Novel Bradykinin-Related Peptide, RVA-Thr6-BK, from the Skin Secretion of the Hejiang Frog; Ordorrana hejiangensis: Effects of Mammalian Isolated Smooth Muscle.

Wu Y, Shi D, Chen X, Wang L, Ying Y, Ma C, Xi X, Zhou M, Chen T, Shaw C.

Toxins (Basel). 2019 Jun 28;11(7). pii: E376. doi: 10.3390/toxins11070376.


Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues.

Zhou X, Shi D, Zhong R, Ye Z, Ma C, Zhou M, Xi X, Wang L, Chen T, Kwok HF.

Biomolecules. 2019 Jun 25;9(6). pii: E249. doi: 10.3390/biom9060249.


LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi.

Li B, Lyu P, Xie S, Qin H, Pu W, Xu H, Chen T, Shaw C, Ge L, Kwok HF.

Biomolecules. 2019 Jun 21;9(6). pii: E242. doi: 10.3390/biom9060242.


A Hylarana latouchii Skin Secretion-Derived Novel Bombesin-Related Pentadecapeptide (Ranatensin-HLa) Evoke Myotropic Effects on the in vitro Rat Smooth Muscles.

Lin Y, Hu N, He H, Ma C, Zhou M, Wang L, Chen T.

Toxins (Basel). 2019 Apr 5;11(4). pii: E204. doi: 10.3390/toxins11040204.


Cloning of a novel trypsin inhibitor from the Traditional Chinese medicine decoction pieces, Radix Trichosanthis.

Sang M, Ying Y, Wu Q, Ma C, Xi X, Zhou M, Wang L, Bininda-Emonds ORP, Chen T.

Anal Biochem. 2019 Aug 1;578:23-28. doi: 10.1016/j.ab.2019.02.028. Epub 2019 Mar 1.


A novel membrane-disruptive antimicrobial peptide from frog skin secretion against cystic fibrosis isolates and evaluation of anti-MRSA effect using Galleria mellonella model.

Yuan Y, Zai Y, Xi X, Ma C, Wang L, Zhou M, Shaw C, Chen T.

Biochim Biophys Acta Gen Subj. 2019 May;1863(5):849-856. doi: 10.1016/j.bbagen.2019.02.013. Epub 2019 Feb 22.


Structure-activity relationship of an antimicrobial peptide, Phylloseptin-PHa: balance of hydrophobicity and charge determines the selectivity of bioactivities.

Liu Y, Du Q, Ma C, Xi X, Wang L, Zhou M, Burrows JF, Chen T, Wang H.

Drug Des Devel Ther. 2019 Jan 23;13:447-458. doi: 10.2147/DDDT.S191072. eCollection 2019.


Phylloseptin-PBa1, -PBa2, -PBa3: Three novel antimicrobial peptides from the skin secretion of Burmeister's leaf frog (Phyllomedusa burmeisteri).

Wu Y, Wang L, Zhou M, Chen T, Shaw C.

Biochem Biophys Res Commun. 2019 Feb 12;509(3):664-673. doi: 10.1016/j.bbrc.2018.12.156. Epub 2019 Jan 3.


Modification Targeting the "Rana Box" Motif of a Novel Nigrocin Peptide From Hylarana latouchii Enhances and Broadens Its Potency Against Multiple Bacteria.

Bao K, Yuan W, Ma C, Yu X, Wang L, Hong M, Xi X, Zhou M, Chen T.

Front Microbiol. 2018 Nov 28;9:2846. doi: 10.3389/fmicb.2018.02846. eCollection 2018.


Novel peptide dermaseptin-PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling.

Long Q, Li L, Wang H, Li M, Wang L, Zhou M, Su Q, Chen T, Wu Y.

J Cell Mol Med. 2019 Feb;23(2):1300-1312. doi: 10.1111/jcmm.14032. Epub 2018 Nov 20.


Evaluating the Bioactivity of a Novel Broad-Spectrum Antimicrobial Peptide Brevinin-1GHa from the Frog Skin Secretion of Hylarana guentheri and Its Analogues.

Chen Q, Cheng P, Ma C, Xi X, Wang L, Zhou M, Bian H, Chen T.

Toxins (Basel). 2018 Oct 13;10(10). pii: E413. doi: 10.3390/toxins10100413.


Skin secretion transcriptome remains in chromatographic fractions suitable for molecular cloning.

Proaño-Bolaños C, Zhou M, Chen T, Shaw C.

Anal Biochem. 2019 Jan 1;564-565:13-15. doi: 10.1016/j.ab.2018.10.006. Epub 2018 Oct 6.


A novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells.

Chen X, Zhang L, Ma C, Zhang Y, Xi X, Wang L, Zhou M, Burrows JF, Chen T.

Biosci Rep. 2018 Nov 9;38(6). pii: BSR20180710. doi: 10.1042/BSR20180710. Print 2018 Dec 21.


Discovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells.

Zhu H, Ding X, Li W, Lu T, Ma C, Xi X, Wang L, Zhou M, Burden R, Chen T.

PeerJ. 2018 Sep 19;6:e5635. doi: 10.7717/peerj.5635. eCollection 2018.


Discovery of Novel Caeridins from the Skin Secretion of the Australian White's Tree Frog, Litoria caerulea.

Li L, Wu Q, Wang X, Lu H, Xi X, Zhou M, Watson CJ, Chen T, Wang L.

Int J Genomics. 2018 Jul 11;2018:8158453. doi: 10.1155/2018/8158453. eCollection 2018.

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