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Items: 1 to 20 of 341

1.

A Direct Measurement of Lateral Molecular Diffusivity on the Surface of Supersaturated Amorphous Solid Dispersions by Atomic Force Microscopy.

Bannow J, Karl M, Larsen PE, Hwu ET, Rades T.

Mol Pharm. 2020 Mar 24. doi: 10.1021/acs.molpharmaceut.0c00176. [Epub ahead of print]

PMID:
32207959
2.

Single particles as resonators for thermomechanical analysis.

Okeyo PO, Larsen PE, Kissi EO, Ajalloueian F, Rades T, Rantanen J, Boisen A.

Nat Commun. 2020 Mar 6;11(1):1235. doi: 10.1038/s41467-020-15028-y.

3.

Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems.

Liu J, Rades T, Grohganz H.

Mol Pharm. 2020 Mar 9. doi: 10.1021/acs.molpharmaceut.0c00042. [Epub ahead of print]

PMID:
32119557
4.

Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition.

Karl M, Thamdrup LHE, Rantanen J, Boisen A, Rades T.

Sensors (Basel). 2020 Feb 13;20(4). pii: E1019. doi: 10.3390/s20041019.

5.

Poorly soluble drugs.

Siepmann J, Rades T, Muellertz A, Loftsson T.

Int J Pharm. 2020 Mar 15;577:119055. doi: 10.1016/j.ijpharm.2020.119055. Epub 2020 Jan 17. No abstract available.

PMID:
31958490
6.

In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin.

Jørgensen JR, Yu F, Venkatasubramanian R, Nielsen LH, Nielsen HM, Boisen A, Rades T, Müllertz A.

Pharmaceutics. 2020 Jan 7;12(1). pii: E48. doi: 10.3390/pharmaceutics12010048.

7.

Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation.

Karl M, Rantanen J, Rades T.

Pharmaceutics. 2019 Dec 10;11(12). pii: E670. doi: 10.3390/pharmaceutics11120670.

8.

Determination of Stable Co-Amorphous Drug-Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures.

Kissi EO, Khorami K, Rades T.

Pharmaceutics. 2019 Nov 24;11(12). pii: E628. doi: 10.3390/pharmaceutics11120628.

9.

Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems.

Tran T, Bønløkke P, Rodríguez-Rodríguez C, Nosrati Z, Esquinas PL, Borkar N, Plum J, Strindberg S, Karagiozov S, Rades T, Müllertz A, Saatchi K, Häfeli UO.

J Control Release. 2020 Jan 10;317:375-384. doi: 10.1016/j.jconrel.2019.11.024. Epub 2019 Nov 23.

PMID:
31765705
10.

Comparison of induction methods for supersaturation: pH shift versus solvent shift.

Plum J, Bavnhøj C, Palmelund H, Pérez-Alós L, Müllertz A, Rades T.

Int J Pharm. 2020 Jan 5;573:118862. doi: 10.1016/j.ijpharm.2019.118862. Epub 2019 Nov 20.

PMID:
31759102
11.

Amino acids as stabilizers for spray-dried simvastatin powder for inhalation.

Lu W, Rades T, Rantanen J, Chan HK, Yang M.

Int J Pharm. 2019 Dec 15;572:118724. doi: 10.1016/j.ijpharm.2019.118724. Epub 2019 Oct 31.

PMID:
31678523
12.

Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis.

Lababidi N, Ofosu Kissi E, Elgaher WAM, Sigal V, Haupenthal J, Schwarz BC, Hirsch AKH, Rades T, Schneider M.

J Control Release. 2019 Nov 28;314:62-71. doi: 10.1016/j.jconrel.2019.10.038. Epub 2019 Oct 22.

PMID:
31654686
13.

Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures.

Streck S, Neumann H, Nielsen HM, Rades T, McDowell A.

Int J Pharm X. 2019 Aug 13;1:100030. doi: 10.1016/j.ijpx.2019.100030. eCollection 2019 Dec.

14.

Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs.

Kissi EO, Ruggiero MT, Hempel NJ, Song Z, Grohganz H, Rades T, Löbmann K.

Phys Chem Chem Phys. 2019 Sep 11;21(35):19686-19694. doi: 10.1039/c9cp01764j.

PMID:
31469369
15.

Self-emulsifying drug delivery systems (SEDDS) - The splendid comeback of an old technology.

Bernkop-Schnürch A, Müllertz A, Rades T.

Adv Drug Deliv Rev. 2019 Mar 1;142:1-2. doi: 10.1016/j.addr.2019.08.002. No abstract available.

PMID:
31446975
16.

Microcontainers for oral insulin delivery - In vitro studies of permeation enhancement.

Jørgensen JR, Jepsen ML, Nielsen LH, Dufva M, Nielsen HM, Rades T, Boisen A, Müllertz A.

Eur J Pharm Biopharm. 2019 Oct;143:98-105. doi: 10.1016/j.ejpb.2019.08.011. Epub 2019 Aug 16.

PMID:
31425857
17.

Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles.

Kłodzińska SN, Wan F, Jumaa H, Sternberg C, Rades T, Nielsen HM.

J Colloid Interface Sci. 2019 Nov 1;555:595-606. doi: 10.1016/j.jcis.2019.08.006. Epub 2019 Aug 3.

PMID:
31404843
18.

The distribution of cell-penetrating peptides on polymeric nanoparticles prepared using microfluidics and elucidated with small angle X-ray scattering.

Streck S, Clulow AJ, Nielsen HM, Rades T, Boyd BJ, McDowell A.

J Colloid Interface Sci. 2019 Nov 1;555:438-448. doi: 10.1016/j.jcis.2019.08.007. Epub 2019 Aug 3.

PMID:
31400536
19.

Controlling the size and shape of liposomal ciprofloxacin nanocrystals by varying the lipid bilayer composition and drug to lipid ratio.

Li T, Clulow AJ, Nowell CJ, Hawley A, Cipolla D, Rades T, Boyd BJ.

J Colloid Interface Sci. 2019 Nov 1;555:361-372. doi: 10.1016/j.jcis.2019.07.081. Epub 2019 Jul 28.

PMID:
31398564
20.

Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats.

Michaelsen MH, Siqueira Jørgensen SD, Abdi IM, Wasan KM, Rades T, Müllertz A.

Eur J Pharm Biopharm. 2019 Sep;142:258-264. doi: 10.1016/j.ejpb.2019.07.002. Epub 2019 Jul 2.

PMID:
31276759

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