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Items: 1 to 20 of 22

1.

A concisely automated synthesis of TSPO radiotracer [18 F]FDPA based on spirocyclic iodonium ylide method and validation for human use.

Wang L, Yao S, Tang R, Zhu H, Zhang L, Gong J, Chen Q, Collier TL, Xu H, Liang SH.

J Labelled Comp Radiopharm. 2020 Jan 2. doi: 10.1002/jlcr.3824. [Epub ahead of print]

PMID:
31895476
2.

Synthesis and Preliminary Evaluation of [11 C]GNE-1023 as a Potent PET Probe for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2) in Parkinson's Disease.

Chen Z, Shao T, Gao W, Fu H, Collier TL, Rong J, Deng X, Yu Q, Zhang X, Davenport AT, Daunais JB, Wey HY, Shao Y, Josephson L, Qiu WW, Liang S.

ChemMedChem. 2019 Sep 4;14(17):1580-1585. doi: 10.1002/cmdc.201900321. Epub 2019 Aug 22.

PMID:
31365783
3.

Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton.

Chen Z, Mori W, Deng X, Cheng R, Ogasawara D, Zhang G, Schafroth MA, Dahl K, Fu H, Hatori A, Shao T, Zhang Y, Yamasaki T, Zhang X, Rong J, Yu Q, Hu K, Fujinaga M, Xie L, Kumata K, Gou Y, Chen J, Gu S, Bao L, Wang L, Collier TL, Vasdev N, Shao Y, Ma JA, Cravatt BF, Fowler C, Josephson L, Zhang MR, Liang SH.

J Med Chem. 2019 Apr 11;62(7):3336-3353. doi: 10.1021/acs.jmedchem.8b01778. Epub 2019 Mar 21.

PMID:
30829483
4.

Microfluidic radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors.

Collier TL, Liang SH, Mann JJ, Vasdev N, Kumar JSD.

Beilstein J Org Chem. 2017 Dec 29;13:2922-2927. doi: 10.3762/bjoc.13.285. eCollection 2017.

5.

Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib.

Collier TL, Normandin MD, Stephenson NA, Livni E, Liang SH, Wooten DW, Esfahani SA, Stabin MG, Mahmood U, Chen J, Wang W, Maresca K, Waterhouse RN, El Fakhri G, Richardson P, Vasdev N.

Nat Commun. 2017 Jun 8;8:15761. doi: 10.1038/ncomms15761.

6.

Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging.

Hu K, Patnaik D, Collier TL, Lee KN, Gao H, Swoyer MR, Rotstein BH, Krishnan HS, Liang SH, Wang J, Yan Z, Hooker JM, Vasdev N, Haggarty SJ, Ngai MY.

ACS Med Chem Lett. 2017 Feb 2;8(3):287-292. doi: 10.1021/acsmedchemlett.6b00405. eCollection 2017 Mar 9.

7.

cGMP production of the radiopharmaceutical [18 F]MK-6240 for PET imaging of human neurofibrillary tangles.

Collier TL, Yokell DL, Livni E, Rice PA, Celen S, Serdons K, Neelamegam R, Bormans G, Harris D, Walji A, Hostetler ED, Bennacef I, Vasdev N.

J Labelled Comp Radiopharm. 2017 May 15;60(5):263-269. doi: 10.1002/jlcr.3496. Epub 2017 Mar 23.

PMID:
28185305
8.

Preclinical PET Neuroimaging of [11C]Bexarotene.

Rotstein BH, Placzek MS, Krishnan HS, Pekošak A, Collier TL, Wang C, Liang SH, Burstein ES, Hooker JM, Vasdev N.

Mol Imaging. 2016 Aug 23;15. pii: 1536012116663054. doi: 10.1177/1536012116663054. Print 2016.

9.

Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis.

Vasdev N, Collier TL.

Pharmaceuticals (Basel). 2016 Aug 17;9(3). pii: E51. doi: 10.3390/ph9030051.

10.

Synthesis of 18F-Arenes from Spirocyclic Iodonium(III) Ylides via Continuous-Flow Microfluidics.

Calderwood S, Collier TL, Gouverneur V, Liang SH, Vasdev N.

J Fluor Chem. 2015 Oct;178:249-253. Epub 2015 Aug 12.

11.

Enhanced copper-mediated (18)F-fluorination of aryl boronic esters provides eight radiotracers for PET applications.

Preshlock S, Calderwood S, Verhoog S, Tredwell M, Huiban M, Hienzsch A, Gruber S, Wilson TC, Taylor NJ, Cailly T, Schedler M, Collier TL, Passchier J, Smits R, Mollitor J, Hoepping A, Mueller M, Genicot C, Mercier J, Gouverneur V.

Chem Commun (Camb). 2016 Jun 28;52(54):8361-4. doi: 10.1039/c6cc03295h.

PMID:
27241832
12.

Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold.

Wang L, Yui J, Wang Q, Zhang Y, Mori W, Shimoda Y, Fujinaga M, Kumata K, Yamasaki T, Hatori A, Rotstein BH, Collier TL, Ran C, Vasdev N, Zhang MR, Liang SH.

ACS Chem Neurosci. 2016 Jan 20;7(1):109-18. doi: 10.1021/acschemneuro.5b00248. Epub 2015 Nov 17.

13.

(18)F-Labeling of Aryl-SCF3, -OCF3 and -OCHF2 with [(18)F]Fluoride.

Khotavivattana T, Verhoog S, Tredwell M, Pfeifer L, Calderwood S, Wheelhouse K, Lee Collier T, Gouverneur V.

Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9991-5. doi: 10.1002/anie.201504665. Epub 2015 Jul 3.

PMID:
26140357
14.

Microfluidic continuous-flow radiosynthesis of [18F]FPEB suitable for human PET imaging.

Liang SH, Yokell DL, Jackson RN, Rice PA, Callahan R, Johnson KA, Alagille D, Tamagnan G, Collier TL, Vasdev N.

Medchemcomm. 2014 Apr 1;5(4):432-435.

15.

Diversity-oriented approach to CF3CHF-, CF3CFBr-, CF3CF2-, (CF3)2CH-, and CF3(SCF3)CH-substituted arenes from 1-(diazo-2,2,2-trifluoroethyl)arenes.

Emer E, Twilton J, Tredwell M, Calderwood S, Collier TL, Liégault B, Taillefer M, Gouverneur V.

Org Lett. 2014 Nov 21;16(22):6004-7. doi: 10.1021/ol5030184. Epub 2014 Nov 7.

PMID:
25379614
16.

Synthesis of [(11)C]Bexarotene by Cu-Mediated [(11)C]Carbon Dioxide Fixation and Preliminary PET Imaging.

Rotstein BH, Hooker JM, Woo J, Collier TL, Brady TJ, Liang SH, Vasdev N.

ACS Med Chem Lett. 2014 Feb 27;5(6):668-72. doi: 10.1021/ml500065q. eCollection 2014 Jun 12.

17.

A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging.

Huiban M, Tredwell M, Mizuta S, Wan Z, Zhang X, Collier TL, Gouverneur V, Passchier J.

Nat Chem. 2013 Nov;5(11):941-4. doi: 10.1038/nchem.1756. Epub 2013 Sep 8.

PMID:
24153372
18.

Rapid microfluidic flow hydrogenation for reduction or deprotection of 18F-labeled compounds.

Liang SH, Collier TL, Rotstein BH, Lewis R, Steck M, Vasdev N.

Chem Commun (Camb). 2013 Oct 9;49(78):8755-7. doi: 10.1039/c3cc45166f.

PMID:
23948863
19.

11CO2 fixation: a renaissance in PET radiochemistry.

Rotstein BH, Liang SH, Holland JP, Collier TL, Hooker JM, Wilson AA, Vasdev N.

Chem Commun (Camb). 2013 Jun 25;49(50):5621-9. doi: 10.1039/c3cc42236d. Epub 2013 May 14. Review.

20.

Metal-free oxidative fluorination of phenols with [18F]fluoride.

Gao Z, Lim YH, Tredwell M, Li L, Verhoog S, Hopkinson M, Kaluza W, Collier TL, Passchier J, Huiban M, Gouverneur V.

Angew Chem Int Ed Engl. 2012 Jul 2;51(27):6733-7. doi: 10.1002/anie.201201502. Epub 2012 May 25. No abstract available.

PMID:
22639017

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